This book includes contributions about mathematics, physics, philosophy of science, economics and finance and resulted from the Summer School “Complexity and Emergence: Ideas, Methods, with a Special Attention to Economics and Finance” held in Lake Como School of Advanced Studies, on 22–27 July 2018. The aim of the book is to provide useful instruments from the theory of complex systems, both on the theoretical level and the methodological ones, profiting from knowledge and insights from leading experts of different communities. It moves from the volume editors' conviction that to achieve progress in understanding socio-economical as well as ecological problems of our complex word such preparation is needed, together with a critical reconsideration of our basic scientific and economical approach. The potential readers are primarily master and doctorate students of mathematics, information sciences, theoretical physics and economics, as well as research workers in those areas, who want to enlarge their spectrum of knowledge towards the area of complexity and emergence. Since ideas and methods of the theory of complex systems also apply to other areas (from engineering and architecture to biology and medicine, e.g.), students and research workers from those areas will also profit from this book.

The transition towards renewable energy sources and “green” technologies for energy generation and storage is expected to mitigate the climate emergency in the coming years. However, in many cases, this progress has been hampered by our dependency on critical materials or other resources that are often processed at high environmental burdens. Yet, many studies have shown that environmental and energy issues are strictly interconnected and require a comprehensive understanding of resource management strategies and their implications. Life cycle assessment (LCA) is among the most inclusive analytical techniques to analyze sustainability benefits and trade-offs within complex systems and, in this Special Issue, it is applied to assess the mutual influences of environmental and energy dimensions. The selection of original articles, reviews, and case studies addressed covers some of the main driving applications for energy requirements and greenhouse gas emissions, including power generation, bioenergy, biorefinery, building, and transportation. An insightful perspective on the current topics and technologies, and emerging research needs, is provided. Alone or in combination with integrative methodologies, LCA can be of pivotal importance and constitute the scientific foundation on which a full system understanding can be reached.

Metastasis is the major cause of mortality in cancer patients. Metastases can be present at the time of diagnosis or can occur years or decades after the removal of the primary tumor and treatment. This long latency in the manifestation of recurrent metastatic disease is explained clinically by the persistence of quiescent tumor cells that disseminated early in the course of the disease from the primary tumor to select distant organs. These residing disseminated tumor cells (DTCs) at distant organs lay dormant and asymptomatic until reawakened to form overt metastases. Importantly, the quiescent nature of these “hibernating” DTCs facilitates their resistance to conventional therapies that target actively dividing tumor cells. Therefore, unraveling the biology of dormancy and reactivation of the residing DTCs to life-threatening lesions is of utmost importance in order to develop new therapeutic strategies to prevent the recurrent metastatic disease from ever emerging or to better treat these recurrent cancers. The mechanisms underlying the biology of tumor dormancy and their reactivation to overt metastases are just beginning to emerge thanks to a growing appreciation of the potentially chronic nature of some cancers and the development of experimental model systems for their study. In this Research Topic, we will follow the journey of circulating tumor cells (CTCs) dispatching from the primary site until their successful lodging into a new and foreign site to become DTCs. We will explore the intrinsic mechanisms along with microenvironmental cues and niches that they encounter during their journey that may dictate their fate.

Revisiting Sustainable Tourism in the Philippines offers a novel perspective about how sustainable tourism can be pursued against the backdrop of the events that have occurred over the years, through four themes: value chain integration, thinking small, customization of services, and quality over quantity.

For some time before his death in July 2015, former colleagues and students of Paul Langford had discussed the possibility of organising a festschrift to celebrate his remarkable contribution to eighteenth-century history. It was planned for 2019 to commemorate the thirtieth anniversary of the appearance of his seminal A Polite and Commercial People, the opening volume in the New Oxford History of England series, Paul's best-known and most influential publication. He was delighted to hear of these plans and the tragic news of his death only made the contributors more determined to see the project through to completion. The importance of A Polite and Commercial People within its own time is unquestionable. Not only did it provide a powerful new vision of eighteenth-century Britain, but it also played a vital part in reviving interest in, and expanding ways of thinking about, Georgian history. As the thirteen contributors to this volume amply testify, any review of the field from the 1980s onwards cannot ignore the profound effect Paul's research had on the social and political publications in his field. This collection of essays combines reflection on the impact of Paul's work with further engagement with the central questions he posed. In particular, it serves to re-connect various recent avenues of Georgian studies, bringing together diverse themes present in Paul's scholarship, but which are often studied independently of each other. As such, it aims to provide a fitting tribute to Paul's work and impact, and a wider reassessment of the current direction of eighteenth-century studies.

Proceedings of the 53rd International Conference of the Architectural Science Association

Revisiting al-Andalus brings together a range of recent scholarship on the material culture of Islamic Iberia, highlighting especially the new directions that have developed in the Anglo-American branch of this field since the 1992 catalogue of the influential exhibition, Al-Andalus: the Art of Islamic Spain. Together with examples of recent Spanish scholarship on medieval architecture and urbanism, the volume’s contributors (historians of art and architecture, archaeologists, and architects) explore topics such as the relationship between Andalusi literature and art; architecture, urbanism, and court culture; domestic architecture; archaeology as a tool for analyzing economic and architectural history; cultural transfer between the Iberian Peninsula and the New World; 19th-century “rediscovery” of al-Andalus; and modern architectural and historiographical attempts to construct an Andalusi cultural identity. Contributors include: Antonio Almagro, Glaire D. Anderson, Rebecca Bridgman, María Judith Feliciano, Kathryn Ferry, Pedro Jiménez, Julio Navarro, Camila Mileto, Antonio Orihuela, Jennifer Roberson, Cynthia Robinson, Mariam Rosser-Owen, Antonio Vallejo Triano, and Fernando Vegas.