The profound transformations occurred in our modern age have been made possible by the unique combination of new technologies. Among them, me- cine has completely changed our perception of life. Longevity has been signi- cantly extended and linked to new lifestyles. The negative impact that pathologies and ageing have always had on the quality of our life is now mitigated by the availability of treatments daily applied to many individuals worldwide. For many years, pharmacological and surgical treatments have been supported by the introduction of biomedical devices. Biomedical implants have played a key role in the development of these treatments and achieved the objective of replacing tissue and organ structures and functionalities. Gra- ally, the scientific and clinical communities have understood that replacement could be improved by materials able to interact with the tissues and to parti- pate in their metabolism and functions. This approach soon led to biomedical implants with improved clinical performances, but also to a new aspiration; rather than replacing damaged tissues and organs scientists and clinicians nowadays aim at their partial or complete regeneration. As a consequence of this ambition, the disciplines of tissue engineering and regenerative medicine have recently emerged. It is the dawn of a fascinating era where scientists from various disciplines, clinicians, and industry will need to intensify their col- borative efforts to provide our society with new and affordable solutions.

Engineering Strategies for Regenerative Medicine considers how engineering strategies can be applied to accelerate advances in regenerative medicine. The book provides relevant and up-to-date content on key topics, including the interdisciplinary integration of different aspects of stem cell biology and technology, diverse technologies, and their applications. By providing massive amounts of data on each individual, recent scientific advances are rapidly accelerating medicine. Cellular, molecular and genetic parameters from biological samples combined with clinical information can now provide valuable data to scientists, clinicians and ultimately patients, leading to the development of precision medicine. Equally noteworthy are the contributions of stem cell biology, bioengineering and tissue engineering that unravel the mechanisms of disease, regeneration and development. - Considers how engineering strategies can accelerate novel advances in regenerative medicine - Takes an interdisciplinary approach, integrating different aspects of research, technology and application - Provides up-to-date coverage on this rapidly developing area of medicine - Presents insights from an experienced and cross-disciplinary group of researchers and practitioners with close links to industry

Proposes a new regenerative strategy that encapsulates cutting-edge climate science solutions and a new purpose for the firm.

This book presents regenerative strategies for the treatment of knee joint disabilities. The book is composed of four main sections totaling 19 chapters which review the current knowledge on the clinical management and preclinical regenerative strategies. It examines the role of different natural-based biomaterials as scaffolds and implants for addressing different tissue lesions in the knee joint. Section one provides an updated and comprehensive discussion on articular cartilage tissue regeneration. Section two focuses on the important contributions for bone and osteochondral tissue engineering. Section three overview the recent advances on meniscus repair/regeneration strategies. Finally, section four further discusses the current strategies for treatment of ligament lesions. Each chapter is prepared by world know expert on their fields, so we do firmly believe that the proposed book will be a reference in the area of biomaterials for regenerative medicine.

Virtually any disease that results from malfunctioning, damaged, or failing tissues may be potentially cured through regenerative medicine therapies, by either regenerating the damaged tissues in vivo, or by growing the tissues and organs in vitro and implanting them into the patient. Principles of Regenerative Medicine discusses the latest advances in technology and medicine for replacing tissues and organs damaged by disease and of developing therapies for previously untreatable conditions, such as diabetes, heart disease, liver disease, and renal failure. - Key for all researchers and instituions in Stem Cell Biology, Bioengineering, and Developmental Biology - The first of its kind to offer an advanced understanding of the latest technologies in regenerative medicine - New discoveries from leading researchers on restoration of diseased tissues and organs

Tendon Regeneration: Understanding Tissue Physiology and Development to Engineer Functional Substitutes is the first book to highlight the multi-disciplinary nature of this specialized field and the importance of collaboration between medical and engineering laboratories in the development of tissue-oriented products for tissue engineering and regenerative medicine (TERM) strategies. Beginning with a foundation in developmental biology, the book explores physiology, pathology, and surgical reconstruction, providing guidance on biological approaches that enhances tendon regeneration practices. Contributions from scientists, clinicians, and engineers who are the leading figures in their respective fields present recent findings in tendon stem cells, cell therapies, and scaffold treatments, as well as examples of pre-clinical models for translational therapies and a view of the future of the field. - Provides an overview of tendon biology, disease, and tissue engineering approaches - Presents modern, alternative approaches to developing functional tissue solutions discussed - Includes valuable information for those interested in tissue engineering, tissue regeneration, tissue physiology, and regenerative medicine - Explores physiology, pathology, and surgical reconstruction, building a natural progression that enhances tendon regeneration practices - Covers recent findings in tendon stem cells, cell therapies, and scaffold treatments, as well as examples of pre-clinical models for translational therapies and a view of the future of the field

Tissue Engineering and Regeneration in Dentistry: Current Strategies presents a thorough update on the current advances, methods and understanding in tissue engineering in dentistry. It offers invaluable tools, case studies, and methodologies for undertaking research, including important biological and practical considerations to facilitate successful migration of research from the bench to the clinic. Offers detailed coverage of the basic underlying principles and scientific evidence, and includes protocols to highlight practical applications Written by an internationally renowned team of expert contributors A must-have read for researchers and specialist clinicians in tissue engineering, oral biology, dental materials science, periodontology and oral surgery

A radically new understanding of and practical approach to climate change by noted environmentalist Paul Hawken, creator of the New York Times bestseller Drawdown Regeneration offers a visionary new approach to climate change, one that weaves justice, climate, biodiversity, equity, and human dignity into a seamless tapestry of action, policy, and transformation that can end the climate crisis in one generation. It is the first book to describe and define the burgeoning regeneration movement spreading rapidly throughout the world. Regeneration describes how an inclusive movement can engage the majority of humanity to save the world from the threat of global warming, with climate solutions that directly serve our children, the poor, and the excluded. This means we must address current human needs, not future existential threats, real as they are, with initiatives that include but go well beyond solar, electric vehicles, and tree planting to include such solutions as the fifteen-minute city, bioregions, azolla fern, food localization, fire ecology, decommodification, forests as farms, and the number one solution for the world: electrifying everything. Paul Hawken and the nonprofit Regeneration Organization are launching a series of initiatives to accompany the book, including a streaming video series, curriculum, podcasts, teaching videos, and climate action software. Regeneration is the inspiring and necessary guide to inform the rapidly spreading climate movement.

Regenerative Biology and Medicine, Second Edition — Winner of a 2013 Highly Commended BMA Medical Book Award for Medicine — discusses the fundamentals of regenerative biology and medicine. It provides a comprehensive overview, which integrates old and new data into an ever-clearer global picture. The book is organized into three parts. Part I discusses the mechanisms and the basic biology of regeneration, while Part II deals with the strategies of regenerative medicine developed for restoring tissue, organ, and appendage structures. Part III reflects on the achievements of regenerative biology and medicine; future challenges; bioethical issues that need to be addressed; and the most promising developments in regenerative medicine. The book is designed for multiple audiences: undergraduate students, graduate students, medical students and postdoctoral fellows, and research investigators interested in an overall synthesis of this field. It will also appeal to investigators from fields not directly related to regenerative biology and medicine, such as chemistry, informatics, computer science, mathematics, physics, and engineering. - Highly Commended 2013 BMA Medical Book Award for Medicine - Includes coverage of skin, hair, teeth, cornea, and central neural tissues - Provides description of regenetive medicine in digestive, respiratory, urogenital, musculoskeletal, and cardiovascular systems - Includes amphibians as powerful research models with discussion of appendage regeneration in amphibians and mammals

Plant Strategies, Vegetation Processes, and Ecosystem Properties, Second Edition, is a thoroughly updated and comprehensive new edition of the very successful Plant Strategies and Vegetative Processes, which controversially proposed the existence of widely-recurring plant functional types with predictable relationships to vegetation structure and dynamics. This second edition uses evidence from many parts of the world to re-examine these concepts in the light of the enormous expansion in the literature. Features include: * A new section covering all aspects of ecosystem properties * New chapters on Assembling of Communities Rarification and Extinction Colonisation and Invasion * Principles and methodologies of a range of international tests including case study examples * Chapter summaries for a quick reference guide * Index of species names Written in a very readable style, this book is an invaluable reference source for researchers in the areas of plant, animal, and community ecology, conservation and land management. 'Written by one of the foremost authorities in the field, summarising over 35 years of research. A book all plant ecologists will want to read.' - Jonathan Silvertown, Department of Biological Sciences, The Open University, UK. 'The coverage is outstanding and comprehensive.' - Simon A. Levin, Department of Ecology and Evolutionary Biology, Princeton University, USA