Reconstitutions of Transporters, Receptors, and Pathological States presents 12 lectures on the resolution and reconstitution of transporters, receptors, and pathological states. Lecture 1 discusses the reconstitution of soluble pathways, and the resolution and reconstitution of membrane complexes. Lecture 2 covers the solubilization and purification of membrane proteins. Lecture 3 explains the functions of protein and phospholipid components; the role of asymmetry; and measurement of scrambling during reconstitution. Lecture 4 presents analyses of reconstituted vesicles while Lectures 5 and 6 examine the properties of F1 and E1E2 pumps, respectively. Lecture 7 focuses on ATP-driven H+ fluxes in organelles and ATP-driven ion pumps of microorganisms and plants. Lecture 8 covers the reconstitution of the mitochondrial electron transport chain; reconstitution of photosynthetic electron transport pathways; and bacteriorhodopsin and halorhodopsin. Lecture 9 discusses the transporters of plasma membranes, mithchondria, and organelles. Lecture 10 deals with plasma membrane receptors. Lecture 11 focuses on the malignant transformation of cells while Lecture 12 speculates on the future of reconstitutions.

The self-assembly of synthetic surfactants and other non-phospholipids into vesicles was first studied in the 1970s by cosmetic scientists when non-ionic surfactant vesicles or niosomes were reported. Since this time a large body of research has sought to define these systems primarily as drug carriers and also as features of interest to the colloid scientist. Synthetic surfactant vesicles, as the name implies, may also be fabricated from a vast array of amphiphiles, including a number of pharmaceutically acceptable materials. They may also be prepared in a variety of shapes and sizes and have a number of applications. This book is designed to serve as an introductory text to the science of non-phospholipid vesicles and will be of use to colloid, drug delivery, cosmetic, and materials scientists. It aims to acquaint the reader with the physicochemistry and biomedical applications of these synthetic surfactant non-phospholipid vesicles. Part one introduces the reader to physicochemical aspects of these synthetic surfactant dispersions and explores the diversity of materials that may be used to formulate vesicles. Part two details methods of vesicle preparation and the application of synthetic surfactant vesicles in a variety of fields ranging from anti-cancer chemotherapy to immunization.

„The Roots of Modern Biochemistry ist eine gute Einführung in die moderne Biochemie, und als Einstieg sehr zu empfehlen.” Prof. Dr. Hans Fritz, Ludwig-Maximilians-Universität München

The 50th volume of Progress in Botany appears in new guise. In cooperation with Springer-Verlag we have changed from the less attractive typewriter composition to the direct reproduction of a manuscript which was writ ten by means of a text editing system and produced by a laser printer. We, the editors, should like to take the appearance of Volume 50 as the occasion for a few short remarks. Our younger readers are perhaps not aware that our Book Series was founded in 1931 by Fritz von Wettstein, based on the following thoughts and considerations, aptly formulated by him in the Preface to the first volume. "One of the greatest dangers threatening progress in the science of botany is the absolutely unbelievable growth in volume of the literature. The quality of journals, books and individual works that are daily sent to us makes it impossible for anyone person to maintain a general view of the progress made in botany in all the specialized fields, let alone to find time for results from associated su bjects. For varying reasons, every botanist must find this state of matters insupportable. Let us endeavor, in the general interest, to retain a wide background of knowledge, and not become limited specialists. The vitally necessary connections between the specialized fields can only flourish, or even exist, if the general view of botany as a whole can be maintained.

New edition of a text in which six researchers from leading institutions discuss what is known and what is yet to be understood in the field of cell biology. The material on molecular genetics has been revised and expanded so that it can be used as a stand-alone text. A new chapter covers pathogens, infection, and innate immunity. Topics include introduction to the cell, basic genetic mechanisms, methods, internal organization of the cell, and cells in their social context. The book contains color illustrations and charts; and the included CD-ROM contains dozens of video clips, animations, molecular structures, and high-resolution micrographs. Annotation copyrighted by Book News Inc., Portland, OR.

Protein-lipid interactions as a field of study is now a mature area, and this volume of NewComprehensive Biochemistry has been published with two objectives in mind. Firstly, to look to thefuture, and try to envisage how the subject may develop in the near to medium future. Secondly, to presentcontrasting or complementary views on the same system. For example, the acetylcholine receptor is discussedfrom a predominantly structural aspect by Barrantes, and from the kinetic standpoint by Rankin, et al.The volume not only gives an update on specific aspects of the field, but also shows the way in whichthe phenomenon of protein-lipid interactions is now seemingly infiltrating many areas of biomembraneresearch, from recombinant DNA studies, protein insertion and assembly and reconstitution considerationsto structural studies of membrane proteins.

Photosynthesis is an active area of research in which many exciting developments have taken place in the last few years. This book gives an overview of the present understanding of all areas of molecular processes of photosynthesis. It is based on the international literature available in the summer of 1986 and much unpublished material. The new material contained in this book, together with a basic framework of established concepts, provide a useful source of reference on the biochemical and biophysical aspects of photosynthesis in plants and bacteria. The book is written by specialists in the various areas of photosynthesis and is useful both for workers in these areas as a source of specialized information as well as for non-photosynthesists who want to become informed about recent developments and basic concepts in this area.

Atomic force microscopy (AFM) is part of a range of emerging microscopic methods for biologists which offer the magnification range of both the light and electron microscope, but allow imaging under the 'natural' conditions usually associated with the light microscope. To biologists, AFM offers the prospect of high resolution images of biological material, images of molecules and their interactions even under physiological conditions, and the study of molecular processes in living systems. This book provides a realistic appreciation of the advantages and limitations of the technique and the present and future potential for improving the understanding of biological systems.The second edition of this bestseller has been updated to describe the latest developments in this exciting field, including a brand new chapter on force spectroscopy. The dramatic developments of AFM over the past ten years from a simple imaging tool to the multi-faceted, nano-manipulating technique that it is today are conveyed in a lively and informative narrative, which provides essential reading for students and experienced researchers alike./a

Ion Transport in Prokaryotes ...