Radiation Research, A Twentieth-Century Perspective, Volume I: Congress Abstracts is a collection of abstracts presented at the Ninth International Congress of Radiation Research convened in Toronto, Canada, organized by the Radiation Research Society and the North American Hyperthermia Group at the invitation of the International Association of Radiation Research. The Toronto venue for this congress recognizes a major role by Canadian scientists in the field of radiation research and also the strong participation of Canadian scientists in the North American Radiation Research Society. Original science is shared at these Congresses through Congress lectures, symposia presentations, and proffered papers. The Congress Board of Directors adopted a proposal that all abstracts of scientific presentations should become a permanent record of the official proceedings of the Congress. In a manner somewhat analogous to the Canadian postal code system, each abstract in this volume is identified at the top left hand corner by a code consisting of both letters and numbers printed on three lines. Line one consists of one letter and two numbers that uniquely identify each scientific event. The second line consists of a double digit number that designates the sequence of presentation within the specific scientific event. The third line consists of a double letter code in which the first letter indicates the day of the week on which abstract material is presented and/or discussed, and the second letter indicates a morning or afternoon session.

Radiation Research, A Twentieth-Century Perspective, Volume I: Congress Abstracts is a collection of abstracts presented at the Ninth International Congress of Radiation Research convened in Toronto, Canada, organized by the Radiation Research Society and the North American Hyperthermia Group at the invitation of the International Association of Radiation Research. The Toronto venue for this congress recognizes a major role by Canadian scientists in the field of radiation research and also the strong participation of Canadian scientists in the North American Radiation Research Society. Origina ...

Congress Proceedings

Growing public concern about releases of radiation into the environment has focused attention on the measurement of exposure of people living near nuclear weapons production facilities or in areas affected by accidental releases of radiation. Radiation-Dose Reconstruction for Epidemiologic Uses responds to the need for criteria for dose reconstruction studies, particularly if the doses are to be useful in epidemiology. This book provides specific and practical recommendations for whether, when, and how studies should be conducted, with an emphasis on public participation. Based on the expertise of scientists involved in dozens of dose reconstruction projects, this volume: Provides an overview of the basic requirements and technical aspects of dose reconstruction. Presents lessons to be learned from dose reconstructions after Chernobyl, Three Mile Island, and elsewhere. Explores the potential benefits and limitations of biological markers. Discusses how to establish the "source term"â€"that is, to determine what was released. Explores methods for identifying the environmental pathways by which radiation reaches the body. Offers details on three major categories of dose assessment.

Biomarkers have emerged as an exciting tool in disease prevention, particularly in the workplace. They may be used to document workers' exposure to toxins, signal the onset of health effects, or identify individuals with susceptibility to certain environmental threats. But the uncertainty is as great as the potential. Are biomarkers suitable for widespread use? How can they be deployed in diverse contexts? How can biological information about workers be handled fairly and ethically? Biomarkers and Occupational Health describes the state of biomarker development, including the implications of the Human Genome program, and presents a range of viewpoints on the future of biomarkers from the leaders in the field. This book explores the three basic types of biomarkers (markers of exposure, markers of health effects, and markers of susceptibility to disease) from a variety of perspectives. It examines what can be learned from well-known exposure sites--Hiroshima and Nagasaki, Chernobyl, and the Hanford nuclear site in the United States, for example--and a wide range of human cases and animal studies. The book also explores the costs and ramifications of developing a large-scale program to monitor potentially exposed workers (e.g., at a cleanup site). A framework is offered for the use of biomarkers based on the mandate to "change the environment before you change the worker." The book explores how to identify ethical issues, how to set development priorities, and how to integrate biomarkers into an occupational health and safety program. The authors present the latest technical findings about markers for chronic beryllium disease as well as markers for exposure to carcinogens, radiation, and chronium--including prospects for detecting long-past exposures. Biomarkers and Occupational Health offers an update on biomarker development and explores a wide scope of issues. This book will be important to occupational health professionals, biomedical researchers, toxicologists, epidemiologists, and labor and management officials involved in worker health issues. Moritmer L. Mendelsohn, M.D., Ph.D., is Vice-Chairman of the Radiation Effects Research Foundation (RERF) in Japan, which studies the long-term health effects of the atomic blasts in Hiroshima and Nagasaki, and he is former Associate Director of the Lawrence Livermore National Laboratory in California. John P. Peeters, Ph.D., is a geneticist who is currently directing a division of the Office of Occupational Medicine for the United States Department of Energy. Mary Janet Normandy, Ph.D., is a toxicologist who specializes in the metabolism of xenobiotics in mammalian systems. She is currently a member of the Department of Energy's Office of Occupational Medicine.

Radon progenyâ€"the decay products of radon gasâ€"are a well-recognized cause of lung cancer in miners working underground. When radon was found to be a ubiquitous indoor air pollutant, however, it raised a more widespread alarm for public health. To develop appropriate public policy for indoor radon, decisionmakers need a characterization of the risk of radon exposure across the range of exposures people actually receive. In response, the BEIR VI committee has developed a mathematical model for the lung cancer risk associated with radon, incorporating the latest information from epidemiology and scientific studies. In this book the committee provides a fresh assessment of exposure-dose relationships. The volume discusses key issuesâ€"such as the weight of biological evidence and extrapolation from radon-exposed miners to the larger populationâ€"in estimating the risk posed by indoor radon. It also addresses such uncertainties as the combined effects of smoking and radon and the impact of the rate of exposure. The committee considered the entire body of evidence on radon and lung cancer, integrating findings from epidemiological studies with evidence from animal experiments and other lines of laboratory investigation. The conclusions will be important to policymakers and environmental advocates, while the technical findings will be of interest to environmental scientists and engineers.

Presenting a monumental achievement: 50 years of data cataloging the immediate, long-term, and hereditary effects of atomic radiation on the survivors of the Hiroshima and Nagasaki bombs. Authored by one of the key members of the Atomic Bomb Casualty Commission founded in 1947, this unique work documents the critical findings and conclusions of the longest ongoing medical study in history; it will surely become the foundation for all future investigations and standards regarding the bioeffects of ionizing radiation. "In my opinion, Dr. Schull has written a very interesting and accurate account of the atomic bomb follow-up program in Japan. He writes extremely well, with areas of his particular scientific interest described in great detail. He also describes events and the social implications in a manner that has broad, general appeal." —Stuart C. Finch, MD University of Medicine and Dentistry of New Jersey "A history of the Hiroshima/Nagasaki study is badly needed. I was very happy to hear that Jack Schull was working on such a project, and it is an understatement to say that I am anxious to see it published." —Seymour Jablon, PhD Bethesda, Maryland "Rarely in the history of a program will one have a nearly 50-year account from an eyewitness and major participant, beginning with the program's onset to the present. Jack's book offers the reader this extraordinary insight into the birth and development of the study of the A-bomb survivors. Moreover, he has served on all major national and international commissions dealing with radiation protection and risk assessment and he interweaves the Japanese studies into the radiation risk issues in a way that few, if any, other contemporary scientists can." —Seymour Abrahamson, PhD Radiation Effects Research Foundation On August 6 and 9, 1945, the only atomic bombs ever used in warfare were dropped on the Japanese cities of Hiroshima and Nagasaki. The destruction and death caused by those bombings presented the world with a vivid portrait of the dangers of the atomic age. However, the thousands of bomb survivors have given scientists a massive, firsthand perspective on the bioeffects of radioactivity. It is the study of these survivors that forms the foundation of the modern understanding of the immediate, long-term, and hereditary consequences of exposure to ionizing radiation. Effects of Atomic Radiation: A Half-Century of Studies from Hiroshima and Nagasaki is the definitive account of the methods, findings, and conclusions of the 50-year study on the survivors of the atomic bomb blasts. It is a truly monumental work, surveying a colossal body of data to offer a comprehensive, unified, and authoritative summary of not only the scientific study itself, but the personal, social, and political factors that have shaped the investigation from its inception. The book goes beyond the simple compilation of facts, giving the reader unique insight into this unprecedented research project and exploring the complex web of subjective perceptions and fears that color popular, national, and even scientific views of radiation exposure in moderate and extreme cases. Authored by Dr. William J. Schull, perhaps the single most influential scientist involved in the studies, this book conveys both his authority and sensitivity. Dr. Schull arrived in Japan in 1949 and was instrumental in the development of the Atomic Bomb Casualty Commission. Since then, he has been one of the driving forces behind the largest medical follow-up study ever undertaken. His years spent working directly with bomb survivors imbue his narrative with a compelling personal history, and his service on numerous national and international committees studying ionizing radiation give him a broad, authoritative perspective on the implications of the ABCC's work. Effects of Atomic Radiation: A Half-Century of Studies from Hiroshima and Nagasaki is first and foremost a scientific work, summarizing the core findings of the definitive study on radiation exposure; while throughout the book, the author provides personal accounts that illustrate the human dimensions of the bombings. In a world where nuclear power is increasing and exposure to radiation is a daily occurrence, this book is essential reading for all scientists associated with public, private, or governmental institutions that set standards of acceptability for exposure.