Psychoendocrinology covers the advances in the field of biology and the development of highly refined measurement techniques for hormones. The book discusses the partitioning of neuroendocrine steroids and peptides between vascular and cerebral compartments; the mechanisms of the female reproductive behavior; and the sensory, hormonal, and neural determinant of maternal behavior. The text describes the effects of sexual behavior on gonadal function in rodents; the hormonal regulation of learning performance; and the hormonal modulation of memory. The psychobiological perspective on the psychoneuroendocrinology of stress and the behavioral effects of the endogenous opioids are also considered. The book further tackles the hormonal interactions on temperature regulation and temperature regulation under modified physiological states. Endocrinologists, psychobiologists, neurologists, neurobiologists, and students taking related courses will find the book useful.

Psychoendokrinologie.

John Money's career constitutes the foundation of pediatric psychoendocrinology. In this book he takes a second look at his publications on many different psychoendocrine syndromes, intersexual or hermaphroditic, with respect to sex, gender, amative orientation, and the "lovemap", (his own designation from an individual's experience of sexuality). His ultimate conclusion is that, from prenatal life onward, demasculization of development is not synonymous with feminization, nor is defeminization synonymous with masculinization. This volume will serve to illuminate the evolution of Dr. Money's work and point the way to future investigations in this field.

The mind-body connection is one of the hottest topics in medicine today, documented by enormous amounts of data regarding hormone effects on the brain and behavior. Yet it is only now -- with the debut of this thought-provoking volume -- that we find an up-to-date, sophisticated reference that focuses on the clinical relevance of behavioral endocrinology and is written for practicing clinicians and researchers. This wide-ranging volume shows how the principles and emerging findings of psychoneuroendocrinology can inform modern clinical practice and lead to new breakthroughs in future science and practice. Here, leading authorities -- internationally respected researchers and practicing clinicians -- review empirical findings in their areas of expertise, highlight the clinical significance of these findings, and provide, wherever appropriate, clinical guidelines for the management of patients. Beginning with a lively history of psychoneuroendocrinology (including its many false starts), this book continues on to discussions of the hypothalamic-pituitary-adrenal axis hormone system, the gonadal hormone system, and the thyroid hormone system from each of the three paths generally used for psychoneuroendocrinological investigation: Alterations in endogenous hormone levels observed in primary psychiatric illness Psychiatric concomitants or sequelae of hormonal dysregulation in primary endocrinologic illness Behavioral effects of exogenously administered hormones or hormone antagonists (both the study of the side effects of hormonal medications and the use of hormones and hormone antagonists as psychotropic medications) An unmatched diversity of topics reveals the full breadth and depth of this volume: diabetes mellitus, corticosteroid effects on mood and cognition, Cushing's syndrome and Addison's disease, oral contraceptives and estrogen replacement therapy, psychiatric illness associated with the menstrual cycle and perimenopause, postpartum behavioral changes, anabolic/androgenic steroid use, and a thorough review of thyroid function in psychiatric disorders. Particularly fascinating are sections on the role of neuropeptides and hypothalamic-releasing factors in psychiatric illness, the use of laboratory tests and imaging procedures in evaluating hormonal function in psychiatric patients, the place of newer "alternative" hormonal medications such as melatonin and DHEA in therapeutics, and a provocative and compelling final chapter on the role stress plays in precipitating illness. Designed for both clinician and researcher-scientist, this richly informative guide will also prove an invaluable addition to graduate courses in neuroscience, neuroendocrinology, the biological basis of behavior, and consultation psychiatry. Neuroscientists/neurologists, endocrinologists, obstetricians/gynecologists, internists, family practitioners, nurses, and interested laypersons round out the wide audience for this remarkable volume.

This up-to-date and important new work describes the relationship between psychological and hormonal factors found in human sexual behavior across the lifespan. The author's discussion of human sexual behavior is organized according to developmental stage, starting with the fetus and concluding with senescence. Persky proposes that human sexual behavior is determined by a variety of factors, e.g. social, psychological, and endocrine, and ascertains the relative contribution of each of these factors to a range of sexual behaviors, attitudes, and feelings. Furthermore, he provides documentation that these determinants are interrelated in reciprocal fashion. In addition, by organizing his material within the Life Development model, Persky is able to present normal and abnormal psychoendocrine relationships which lead to sexual disorders.

Genetic Steroid Disorders, Second Edition targets adult and pediatric endocrinologists, clinical geneticists, genetic counselors, reproductive endocrinologists, neonatologists, urologists, and psychoendocrinologists. It is designed to assist these specialists in the diagnosis and treatment of steroid disorders. This revision includes a new chapter on "Gonadotropins, Obesity and Bone" and new research on non-invasive prenatal diagnosis with cell-free DNA. Chapters are thoroughly updated covering steroid disorders, the genetic bases for the disorder and case presentations, This definitive reference belongs in every medical library! - Presents a comprehensive, translational look at all aspects of genetic steroid disorders in one reference work - Provides a common language for endocrinologists, geneticists, molecular pathologists, and genetic counselors to discuss and diagnose genetic steroid disorders Saves clinicians and researchers time in quickly accessing the very latest details on genetic tests and diagnoses as opposed to searching through thousands of journal articles - Highlights significant discoveries with clinical relevance, presenting insight into which medications to use based on the genetic makeup of a patient - Teaches the best strategies and most effective use of genetic information in the patient counseling setting

Stress and Distress in Response to Psychosocial Stimuli is a book based on a study spanning over four years about the different psychosocial stimuli and the body's different reactions towards them, especially stress and disease. The book includes a short introduction to psychosocial stimuli and its physiological mechanisms, psychophysiological reactions; psychosomatic research; and psychosocially mediated disease and its hypotheses. Also covered are the study's methodological considerations; sympathoadrenomedullary responses to pleasant and unpleasant pyschosocial stimuli; sympathoadrenomedullary activity; the effects of work conditions; the emotional reactions during visual stimulation; stressor-induced changes to plasma lipids; and the psychological and physiological reactions and psychomotor performance during prolonged and complex stressor exposure. The text is recommended for psychologists and medical doctors, especially those who wish to study further about psychosocial stimuli and what it can do to the human body.

This book focuses on the assessment and treatment of patients with somatic symptoms, based on biopsychosociospiritual model. Specific assessment skills and treatment techniques are required to approach them effectively. A broad spectrum of knowledge about stress is also needed because stress is closely related to the onset and course of disorders with somatic symptoms. This book consists of four parts. Part 1 ‘Stress’ explores stress, vulnerability, and resilience; intermediate mechanisms between stress and illnesses such as psychoendocrinology and psychoimmunology; the measurement of stress; and the relationship between stress and accidents. Part 2 ‘Somatization’ deals with the concept, mechanisms, assessment, and treatment of somatization. In addition, somatic symptom and related disorders in DSM-5 is included. However, the approach to chronic pain is separately added to this part because pain is a major concern for patients with these disorders. Part 3 ‘Specific physical disorders’ mainly deals with common and distressing functional physical disorders as well as major physical disorders. Therapeutic approach for individuals at risk of coronary heart disease is also included. Part 4 ‘Religion, spirituality and psychosomatic medicine’ emphasizes the importance of a biopsychosociospiritual perspective in an approach for patients with somatic symptoms, especially depressed patients with physical diseases and patients with terminal illnesses because of the growing need for spirituality in such patients. This book explores stress and a variety of issues relevant to the assessment and treatment of disorders with somatic symptoms in terms of biopsychosociospiritiual perspectives. It will be of interest to researchers and healthcare practitioners dealing with stress, health and mental health.