Mental disorders and cardiac diseases are dynamically interrelated. Shared processes include neuro-hormonal, physiological, behavioral, cognitive, social and genetic/ epigenetic factors that have an impact on both psycho-cardiologic health and disease. Beyond co-morbidity during (sub-) acute illness states, the childhood origins of adult mental disorders and cardiovascular diseases are increasingly recognized.

This unique book will help psychiatrists to understand better the risks of cardiovascular illness and cardiologists to appreciate possible pathophysiological links with psychiatric conditions. It describes the common psychiatric conditions, their key features and how they may influence cardiovascular disease, outcomes, and quality of life. It also considers the cardiovascular complications that may arise as a result of mental illness. In an exciting, collaborative approach, psychiatrists and cardiologists combine their expertise throughout the book to provide guidance on the best way to manage such patients, considering the patient as a whole, not the individual conditions.

This handbook brings together the full weight of contemporary evidence bearing on what is now commonly termed “psycho-cardiology”. It focuses on the role of psycho-social factors in the genesis and clinical management of cardiovascular disease (CVD). The book constitutes a critically reviewed compendium of current knowledge in the area, coupled with guides to evidence-based best practice in the field of psycho-cardiology. The following categories are covered: Social/demographic risk for CVD, Personality and CVD risk, Stress and CVD risk, Psychopathology (particularly affective disorders) and CVD risk, The psychological management of those with clinical CVD, Psychology in the prevention of CVD. The book integrates the evidence into a compelling argument that clinicians, researchers and those in public health will discount the role of psychological factors in regard to CVD at their own peril. And importantly for clinicians charged with the care of patients with CVD, the book poses the argument that failure to recognize the links between psychological factors and CVD may well be at the considerable peril of those patients under their care.

Inflammation has invaded the field of psychiatry. The finding that cytokines are elevated in various affective and psychotic disorders brings to the forefront the necessity of identifying the precise research domain criteria (RDoCs) that inflammation is responsible for. This task is certainly the most advanced in major depressive disorders. The reason is that a dearth of clinical and preclinical studies has demonstrated that inflammation can cause symptoms of depression and conversely, cytokine antagonists can attenuate symptoms of depression in medical and psychiatric patients with chronic low grade inflammation. Important knowledge has been gained on the symptom dimensions that inflammation is driving and the mechanisms of action of cytokines in the brain, providing new targets for drug research and development. The aim of the book “Inflammation-Associated Depression” is to present this field of research and its implications in a didactic and comprehensive manner to basic and clinical scientists, psychiatrists, physicians, and students at the graduate level.

This book brings together a cutting edge international team of contributors to critically review the current knowledge regarding the effectiveness of training interventions designed to improve cognitive functions in different target populations. There is substantial evidence that cognitive and physical training can improve cognitive performance, but these benefits seem to vary as a function of the type and the intensity of interventions and the way training-induced gains are measured and analyzed. This book further fulfills the need for clarification of the mechanisms underlying cognitive and neural changes occurring after training. This book offers a comprehensive overview of empirical findings and methodological approaches of cognitive training research in different cognitive domains (memory, executive functions, etc.), types of training (working memory training, video game training, physical training, etc.), age groups (from children to young and older adults), target populations (children with developmental disorders, aging workers, MCI patients etc.), settings (laboratory-based studies, applied studies in clinical and educational settings), and methodological approaches (behavioral studies, neuroscientific studies). Chapters feature theoretical models that describe the mechanisms underlying training-induced cognitive and neural changes. Cognitive Training: An Overview of Features and Applications will be of interest to researchers, practitioners, students, and professors in the fields of psychology and neuroscience.

This book offers a resource to aid in implementing psychosocial screening, assessment, and consequently integrating prevention, care and treatment (i.e. pharmacological, psychosocial rehabilitation and psychotherapeutic) in medicine. It is becoming increasingly recognized that one method of combating spiraling health care costs in developed nations is to integrate psychiatric care into medicine including primary care settings. This volume reviews the main issues relative to the paradigm of a person-centered and recovery-oriented approach that should imbue all medical areas and specialties. It proposes integration methods in screening and assessment, clinimetric approach, dignity conserving care, cross-cultural and ethical aspects, treatment and training as a basic and mandatory need of a whole psychosomatic approach bridging the several specialties in medicine. As such, the book addresses a topic that all physicians, including primary care and psychiatric professionals in a wide variety of mental health settings are currently discussing, planning and preoccupied with, namely the task of integrating mental health into all the medical fields, including primary care, cardiology, psychiatry, oncology and so on.

This book, designed for professionals, introduces a psychobiological model for understanding the paths that lead people to illness and provides recommendations for alterations of maladaptive pathways so that health is regained. Research findings are incorporated to identify causal variables for illness that can be targets for change. Evidence based recommendations for healthy behaviors and therapies are described. Throughout the book, the authors emphasize recognition of turning points on the path to illness that, through informed decision making and implementation of behavioral change, can be re-directed to pathways to health. This book presents case material to illustrate the directions that lead people to illness or to health. The pathways metaphor provides an organizing force, both in addressing variables contributing to illness onset, and in identifying interventions to restore health. This approach will guide the clinician to understanding how people become ill and the types of interventions that are appropriate for stress related illnesses. The clinician will also become better informed about ways to help clients make better decisions, mobilize clients’ survival skills, and implement an interactive model of care. The book includes chapters on stress-related illnesses with high prevalence in today’s society. For each illness, the genetic-psychobiological etiology is explored with enough detail so that the clinician understands the best method of patient assessment and treatment. One of the strengths of the book is the step-wise system of interventions that are applied to the stress-related illnesses. Beginning with re-establishment of normal daily psychobiological rhythms and continuing to evidence based state of the art interventions, the professional is presented with detailed intervention plans. For example, the section on "Applications to common illnesses: metabolic disorders of behavior: diabetes, hypertension, and hyperlipidemia" considers the confluence of genetics, behavior, and maladaptive mind body interactions to produce the metabolic syndrome. Then the personal and professional assessments are described to establish the baseline for recommending treatment while fully engaging the patient. Finally, multilevel interventions are formulated for these disorders. The plan begins with clinician guided self care recommendations to re-establish the normal rhythm of appetite and satiety. The next level of interventions consists of skill building techniques, such as relaxation and imagery. Lastly, psychotherapy and advanced applied psychophysiological interventions are detailed. Case examples are used throughout to illustrate the pathways to illness, the turning points, and the pathways to health. From the patients’ viewpoints, the pathways metaphor is a motivator. The patient is guided to understand the paths that led to illness. Subsequently, the patient becomes empowered by the pathways framework to begin to make choices that lead to health.

Undoubtedly this symposium will prove to be an important landmark in the development of our understanding of the psychopathology of human adaptation in general, as well as of the general adaptation syndrome and stress in particular. It was organized to give an opportunity to an international group of experts on adaptation and stress research to present summaries of their research that could then later be exhaustively analyzed. The carefully structured program brings out three major aspects of adapta tion to stress in experimental animals and man. The first section deals with the neurophysiology of stress responses, placing major emphasis upon the neuroanatomical and neurochemical aspects involved. The second section is devoted to the psychology and psychopathology of adaptive learning, motivation, anxiety, and stress. The third section examines the role played by stress in the pathogenesis of mental diseases. Many of the relevant subjects receive particularly detailed attention. Among these, the following are especially noteworthy: The existence of reward and drive neurons. Constitutional differences in physiological adaptations to stress and d- tress. Motivation, mood, and mental events in relation to adaptive processes. Peripheral catecholamines and adaptation to underload and overload. Selective corticoid and catecholamine responses to various natural stimuli. The differentiation between eustress and distress. Resistance and overmotivation in achievement-oriented activity. The dynamics of conscience and contract psychology. Sources of stress in the drive for power. Advances in the therapy of psychiatric illness. The application of experimental studies on learning to the treatment of neuroses.