Primer on Cerebrovascular Diseases, Second Edition, is a handy reference source for scientists, students, and physicians needing reliable, up-to-date information on basic mechanisms, physiology, pathophysiology, and medical issues related to brain vasculature. The book consists of short, specific chapters written by international experts on cerebral vasculature, presenting the information in a comprehensive and easily accessible manner. Numerous changes have occurred in the field since the publication of the first edition in 1997, particularly our understanding of the genetic aspects of cerebrovascular disease. This updated edition reflects the advances made over the last two decades, not only demonstrating the promise for therapy, but also for a molecular understanding of cerebrovascular diseases. The new edition includes new and expanded topics, including carotid stenting, Iatrogenic causes of stroke, axonal transport and injury, RNAIs, proteomics, and more. 2018 BMA Medical Book Awards Highly Commended in Neurology. - Provides concise chapters on topics in cerebral blood flow and metabolism, pathogenesis of cerebrovascular disorders, diagnostic testing, and management in a comprehensive and accessible format - Written by international leading authorities on cerebral vasculature - Provides up-to-date information on practical applications of basic research and the main clinical issues facing the community, such as axonal transport and proteomics

Ideal for use in rapid-response arenas, this how-to guide helps clinicians identify a range of ECG abnormalities, refine the differential diagnosis, and choose the best intervention. Introductory chapters address simple concepts needed to evaluate normal 12-lead ECGs; subsequent chapters present specialized criteria needed to interpret abnormal ECGs. Differential diagnosis is presented in an organized step-by-step manner. Hundreds of easy-to-understand diagrams link anatomic information with ECG findings. Practice ECGs with answers appear at the end of each abnormality chapter. A brand-new chapter in this edition contains 25 arrhythmia strips to help readers practice and test their interpretive skills.

Contains 597 computer-assisted instructional programs for nursing education and reference (from 1995).

Interpreting an ECG correctly and working out what to do next can seem like a daunting task to the non-specialist, yet it is a skill that will be invaluable to any doctor, nurse or paramedic when evaluating the condition of a patient. Making Sense of the ECG has been written specifically with this in mind, and will help the student and more experienced healthcare practitioner to identify and answer crucial questions. This popular, easy-to-read and easy-to-remember guide to the ECG as a tool for diagnosis and management has been fully updated in its fifth edition to reflect the latest guidelines.

Now in its 5th Edition -- the ECG-2011 Pocket Brain has been expanded and greatly enhanced from its previous edition. Aimed for beginning, novice and experienced interpreters. User-friendly format preserved. * ALL content updated with addition of 12 new pages and over 20 new illustrative figures and tracings. New pages on AV blocks: Brugada syndrome; Acute MI; Torsades. Expanded covergage of tachycardia; MI diagnosis when there is BBB; RVH.

In tissue engineering, the ultimate goal is to engineer an entire functioning organ that requires building complex structures of different tissue types. A three-dimensional scaffold seeded with desired cell types. In order to resemble the natural formations of the organs, cells have to be correctly located in relation to one another. It has been shown in cocultures that cells have the capability of spontaneous tissue-like organization when seeded into the scaffold. The ideal scaffolds should have an interconnected porous structure, well-designed pore size and adequate porosity to allow cell attachment, proliferation and differentiation. Moreover, effective bioactive agents and nutrient exchange are crucial during new tissue development. Thus the individual organ cell is a specific mechanism for the construction or regeneration of the cells. Artificial scaffolds have been applied and used as supporting structures for cell cultures as well as for the domination of cell growth in the repair of impaired tissues or organs. During the cell regeneration, the scaffold temporarily helps in cell regeneration and gradually biodegrade either in the course of the healing process or after, and a new tissue with a desired shape and properties is produced. The challenge of tissue engineering is to mimic what happens in nature. Attempts are being made to engineer in vitro practically every tissue and organ in the body. Work is proceeding in creating tissue-engineered liver, nerve, kidney, intestine, pancreas, and even heart muscle and valves. In the area of connective tissues, work has been ongoing worldwide for many years in the engineering of tendon, ligament, bone, and cartilage. Recently, the number of reports was succeeded in skin, bladder, airway, and bone, where tissue-engineered constructs have been used successfully in patients. This Research Topic is the collection of body organ regeneration materials and their cell adhesion and migration for the development and regeneration of tissues. Biomimetic materials promise to advance in current understanding of organ regeneration and repair by providing tools to recapitulate and monitor relevant properties of cellular - microenvironment interactions. Although cell adhesion, migration, and development aspects of tissues have shown success in the clinic, better, more intricate models are needed to understand drivers of tissue repair and regeneration fully. Tissue engineering bears tremendous potential toward gaining a complete understanding of the underlying biological and physical mechanisms advancing the treatment of damaged organs. The following Research Topic “Bio-mimetic materials for tissue regenerations” discusses examples of progress toward this objective. • Bio-mimicking scaffold materials for tissue regeneration • Cell adhesion to scaffold materials • Role of materials for the migration of cells • Mechanisms of cell growth for organ development