Filling a gap for a pre-clinical phase revision guide, this book will help medics pass their intermediate exams in order to proceed to the clinical years. It is based on the SAQs, EMQs and MCQ school curriculum as set out by the GMC. By covering each module individually but also integrating other disciplines of medicine into the questions, it helps students to think laterally as well as thoroughly revising each module. With a minimum of 4 SAQs, 7 MCQs and 3 EMQs in each chapter, this book offers comprehensive revision practice as well as providing all the answers with clear explanations.

Medical school is full of unfamiliar and often frightening experiences for students. In the first year, a student must move away from home, balance personal finances, assimilate large volumes of information, learn practical skills, pass high stakes exams, and face a range of unique experiences. The Oxford Handbook for Medical School provides an essential, practical guide for all students, whether you have just received your offer, you're eager to succeed on the wards, or you're about to start your final exams. This handbook includes quick-access summaries covering the crucial information for your preclinical years and for each clinical specialty. With bullet lists of the key information you need to know, and helpful mnemonics throughout, this is a concise yet thoroughly comprehensive guide. Written by a team of consultants and recent students, now successfully graduated and embarking on their careers, this book will be your closest companion right up to graduation. More than a survival guide, it will help you navigate the bewildering range of opportunities medical school offers, showing you how to make the most of your time, so you are fully prepared for your future career.

Preclinical medicine provides budding doctors with a platform from which they can launch themselves into the realm of clinical medicine. RevMED 400 SBAs in Preclinical Medicine has been designed by current preclinical medical students and junior doctors to help students develop a solid understanding of physiology and biochemistry such that they can, thereafter, better understand pathology and the management of disease.Containing 400 high-quality single best answer questions, covering a breadth of topics in preclinical medicine, and accompanied by detailed yet succinct and student-friendly explanations; this book will be ideal for students studying preclinical medicine or biomedical sciences.RevMED 400 SBAs in Preclinical Medicine is part of a series. Students can go on to use RevMED 300 SBAs in Medicine and Surgery and RevMED 300 SBAs in Clinical Specialties and enjoy the style and quality of the content throughout their medical school journey.

Translational Medicine: Optimizing Preclinical Safety Evaluation of Biopharmaceuticals provides scientists responsible for the translation of novel biopharmaceuticals into clinical trials with a better understanding of how to navigate the obstacles that keep innovative medical research discoveries from becoming new therapies or even making it to clinical trials. The book includes sections on protein-based therapeutics, modified proteins, oligonucleotide-based therapies, monoclonal antibodies, antibody–drug conjugates, gene and cell-based therapies, gene-modified cell-based therapies, combination products, and therapeutic vaccines. Best practices are defined for efficient discovery research to facilitate a science-based, efficient, and predictive preclinical development program to ensure clinical efficacy and safety. Key Features: Defines best practices for leveraging of discovery research to facilitate a development program Includes general principles, animal models, biomarkers, preclinical toxicology testing paradigms, and practical applications Discusses rare diseases Discusses "What-Why-When-How" highlighting different considerations based upon product attributes. Includes special considerations for rare diseases About the Editors Joy A. Cavagnaro is an internationally recognized expert in preclinical development and regulatory strategy with an emphasis on genetic medicines.. Her 40-year career spans academia, government (FDA), and the CRO and biotech industries. She was awarded the 2019 Arnold J Lehman Award from the Society of Toxicology for introducing the concept of science-based, case-by-case approach to preclinical safety evaluation, which became the foundation of ICH S6. She currently serves on scientific advisory boards for advocacy groups and companies and consults and lectures in the area of preclinical development of novel therapies. Mary Ellen Cosenza is a regulatory toxicology consultant with over 30 years of senior leadership experience in the biopharmaceutical industry in the U.S., Europe, and emerging markets. She has held leadership position in both the American College of Toxicology (ACT) and the International Union of Toxicology (IUTOX) and is also an adjunct assistant professor at the University of Southern California where she teaches graduate-level courses in toxicology and regulation of biologics.

This volume details reviews and protocols on the development and analysis of both cellular and animal-based pre-clinical models in a number of medical areas, including metabolic disorders, longevity, cancer, heart disease and psychiatric disorders. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Pre-Clinical Models: Techniques and Protocols aims to provide methods that describe the context of specific disease or therapeutic areas.

Preclinical Drug Development, Second Edition discusses the broad and complicated realm of preclinical drug development. Topics range from assessment of pharmacology and toxicology to industry trends and regulatory expectations to requirements that support clinical trials. Highlights of the Second Edition include: PharmacokineticsModeling and simula

Maps onto the SAQs, EMQs and MCQ school curriculum as set out by the GMC. Covers each module individually but also integrates other medical disciplines into the questions, helping students to think laterally as well as thoroughly revising each module. Minimum of 4 SAQs, 7 MCQs and 3 EMQs in each chapter

A Comprehensive Guide to Toxicology in Preclinical Drug Development is a resource for toxicologists in industry and regulatory settings, as well as directors working in contract resource organizations, who need a thorough understanding of the drug development process. Incorporating real-life case studies and examples, the book is a practical guide that outlines day-to-day activities and experiences in preclinical toxicology. This multi-contributed reference provides a detailed picture of the complex and highly interrelated activities of preclinical toxicology in both small molecules and biologics. The book discusses discovery toxicology and the international guidelines for safety evaluation, and presents traditional and nontraditional toxicology models. Chapters cover development of vaccines, oncology drugs, botanic drugs, monoclonal antibodies, and more, as well as study development and personnel, the role of imaging in preclinical evaluation, and supporting materials for IND applications. By incorporating the latest research in this area and featuring practical scenarios, this reference is a complete and actionable guide to all aspects of preclinical drug testing. - Chapters written by world-renowned contributors who are experts in their fields - Includes the latest research in preclinical drug testing and international guidelines - Covers preclinical toxicology in small molecules and biologics in one single source

Lippincott® Connect Featured Title The perfect, one-of-a-kind companion to clerkship bootcamps, dedicated courses, or independent study, The Pre-Clerkship Guide: Procedures and Skills for Clinical Rotations delivers clear guidance on fundamental skills and basic clinical procedures essential for success in clinical rotations. Concise, step-by-step instructions and supplemental illustrations detail need-to-know information at a glance for quick reference when studying or practicing in a clinical setting, accompanied by professional insights and examples that highlight effective application. Whether paired with Bates’s Pocket Guide or used as a standalone resource, this compact, easy-to-use text reinforces key information in a cohesive approach to help students feel comfortable and confident in clinical settings.

Perfect for new teachers in undergraduate, postgraduate, or continuing education, as well as more experienced educators who want to assess, improve, and gain new perspectives on teaching and learning, Essential Skills for a Medical Teacher is a useful, easy-to-read professional resource. This book offers a concise introduction to the field of medical education, with key coverage of educational models and theory that can help inform teaching practice. Clear illustrations and practical tips throughout make it an excellent starting point for those new to the field of medical education or who want to facilitate more effective learning for their students or trainees. Provides hints drawn from practical experience that help you create powerful learning opportunities for your students, with readable guidelines and new techniques that can be adopted for use in any teaching program. Includes new coverage of "just-in-time" learning, entrustable professional activities, steps on introducing outcome/competency-based education, selecting a teaching method, programmatic assessment, self-assessment, the student and patient as partners in the education process, the changing role of the teacher, bringing about change, and the future of medical education. Covers recent developments in our understanding of the relationship between learning and technology, as well as curriculum planning and curriculum mapping. Offers practical advice from leading international expert Professor Ronald Harden and co-author Jennifer Laidlaw, who has designed and taught many courses for medical teachers. Prompts you to reflect on your own performance as an educator, as well as analyze with colleagues the different ways that your work can be approached and how your students’ or trainees’ learning can be made more effective.