This book deals with polymorphism - the existence of different solid structures of the same chemical entity (for example graphite and diamond, both composed of carbon) which provide ideal systems for investigating the relationship between the structure and properties of a wide variety of materials.

"Polymorphism in the Pharmaceutical Industry - Solid Form and Drug Development" highlights the relevance of polymorphism in modern pharmaceutical chemistry, with a focus on quality by design (QbD) concepts. It covers all important issues by way of case studies, ranging from properties and crystallization, via thermodynamics, analytics and theoretical modelling right up to patent issues. As such, the book underscores the importance of solid-state chemistry within chemical and pharmaceutical development. It emphasizes why solid-state issues are important, the approaches needed to avoid problems and the opportunities offered by solid-state properties. The authors include true polymorphs as well as solvates and hydrates, while providing information on physicochemical properties, crystallization thermodynamics, quantum-mechanical modelling, and up-scaling. Important analytical tools to characterize solid-state forms and to quantify mixtures are summarized, and case studies on solid-state development processes in industry are also provided. Written by acknowledged experts in the field, this is a high-quality reference for researchers, project managers and quality assurance managers in pharmaceutical, agrochemical and fine chemical companies as well as for academics and newcomers to organic solid-state chemistry.

Edited by one of the leading experts in the field, this handbook emphasizes why solid-state issues are important, which approaches should be taken to avoid problems and exploit the opportunities offered by solid state properties in the pharmaceutical and agricultural industries. With its practical approach, this is at once a guideline for development chemists just entering the field as well as a high-quality source of reference material for specialists in the pharmaceutical and chemical industry, structural chemists, physicochemists, crystallographers, inorganic chemists, and patent departments.

The objective of this Genetic Polymorphisms book is to rehighlight and provide few updates on the role of genetic polymorphisms in medicine and agriculture, which void emerging opinion on "full death" of genetic polymorphisms as useful genetic markers. Chapters presented here demonstrate the future benefit of SNPs in many genetic studies as well as prognosis disease and diagnosis.

All aboard The Coding Train! This beginner-friendly creative coding tutorial is designed to grow your skills in a fun, hands-on way as you build simulations of real-world phenomena with “The Coding Train” YouTube star Daniel Shiffman. What if you could re-create the awe-inspiring flocking patterns of birds or the hypnotic dance of fireflies—with code? For over a decade, The Nature of Code has empowered countless readers to do just that, bridging the gap between creative expression and programming. This innovative guide by Daniel Shiffman, creator of the beloved Coding Train, welcomes budding and seasoned programmers alike into a world where code meets playful creativity. This JavaScript-based edition of Shiffman’s groundbreaking work gently unfolds the mysteries of the natural world, turning complex topics like genetic algorithms, physics-based simulations, and neural networks into accessible and visually stunning creations. Embark on this extraordinary adventure with projects involving: A physics engine: Simulate the push and pull of gravitational attraction. Flocking birds: Choreograph the mesmerizing dance of a flock. Branching trees: Grow lifelike and organic tree structures. Neural networks: Craft intelligent systems that learn and adapt. Cellular automata: Uncover the magic of self-organizing patterns. Evolutionary algorithms: Play witness to natural selection in your code. Shiffman’s work has transformed thousands of curious minds into creators, breaking down barriers between science, art, and technology, and inviting readers to see code not just as a tool for tasks but as a canvas for boundless creativity. Whether you’re deciphering the elegant patterns of natural phenomena or crafting your own digital ecosystems, Shiffman’s guidance is sure to inform and inspire. The Nature of Code is not just about coding; it’s about looking at the natural world in a new way and letting its wonders inspire your next creation. Dive in and discover the joy of turning code into art—all while mastering coding fundamentals along the way. NOTE: All examples are written with p5.js, a JavaScript library for creative coding, and are available on the book's website.

This book provides a glimpse into the dynamic process of genetic polymorphism by presenting studies carried out on different kinds of organisms at the DNA level or gene expression level. Chapters address such topics as genetic polymorphism in animals, gametocyte biomarkers, thrombotic disorders, prostate cancer, and more.

Resulting from a Royal Society discussion meeting, this volume presents a short review of the topic of parasite-host co-evolution. Current thinking on evolution in parasites, viruses and other pathogens is discussed.

The book in your hands presents chapters revealing the magnitude of genetic polymorphisms that exist in different kinds of living beings. Natural populations contain a considerable amount of genetic change, which provides a genomic flexibility that can be used as a raw material for adaptation to changing environmental conditions. The analysis of genetic polymorphisms provides information about DNA sequence changes at a given locus. The increasing availability of PCR-based molecular markers allows for the detailed analyses and the detection of genetic changes influencing some important traits. The purpose of this book is to provide a glimpse into the dynamic process of genetic polymorphisms by presenting the thoughts of scientists engaged in the generation of new ideas and techniques employed for the assessment of genetic polymorphisms. The book should prove useful to students, researchers and experts in the area of molecular genetics.

Get a grounding in polymorphism and other fundamental aspects of object-oriented program design and implementation, and learn a subset of design patterns that any practicing Java professional simply must know in today’s job climate. Java Program Design presents program design principles to help practicing programmers up their game and remain relevant in the face of changing trends and an evolving language. The book enhances the traditional design patterns with Java's new functional programming features, such as functional interfaces and lambda expressions. The result is a fresh treatment of design patterns that expands their power and applicability, and reflects current best practice. The book examines some well-designed classes from the Java class library, using them to illustrate the various object-oriented principles and patterns under discussion. Not only does this approach provide good, practical examples, but you will learn useful library classes you might not otherwise know about. The design of a simplified banking program is introduced in chapter 1 in a non-object-oriented incarnation and the example is carried through all chapters. You can see the object orientation develop as various design principles are progressively applied throughout the book to produce a refined, fully object-oriented version of the program in the final chapter. What You'll Learn Create well-designed programs, and identify and improve poorly-designed ones Build a professional-level understanding of polymorphism and its use in Java interfaces and class hierarchies Apply classic design patterns to Java programming problems while respecting the modern features of the Java language Take advantage of classes from the Java library to facilitate the implementation of design patterns in your programs Who This Book Is For Java programmers who are comfortable writing non-object-oriented code and want a guided immersion into the world of object-oriented Java, and intermediate programmers interested in strengthening their foundational knowledge and taking their object-oriented skills to the next level. Even advanced programmers will discover interesting examples and insights in each chapter.