Serves as a guide for seasoned researchers and students alike, who wish to learn about the cross-fertilization between biology and materials that is driving this emerging area of science This book covers the most relevant topics in basic research and those having potential technological applications for the field of biopolymer brushes. This area has experienced remarkable increase in development of practical applications in nanotechnology and biotechnology over the past decade. In view of the rapidly growing activity and interest in the field, this book covers the introductory features of polymer brushes and presents a unifying and stimulating overview of the theoretical aspects and emerging applications. It immerses readers in the historical perspective and the frontiers of research where our knowledge is increasing steadily—providing them with a feeling of the enormous potential, the multiple applications, and the many up-and-coming trends behind the development of macromolecular interfaces based on the use of polymer brushes. Polymer and Biopolymer Brushes: Fundamentals and Applications in Materials offers chapters on: Functionalization of Surfaces Using Polymer Brushes; Polymer Brushes by ATRP and Surface-Mediated RAFT Polymerization for Biological Functions; Electro-Induced Copper Catalyzed Surface Modification with Monolayer and Polymer Brush; Polymer Brushes on Flat and Curved Substrates; Biomimetic Anchors for Antifouling Polymer Brush Coating; Glycopolymer Brushes Presenting Sugars in Their Natural Form; Smart Surfaces Modified with Phenylboronic Acid-Containing Polymer Brushes; DNA Brushes; Polymer Brushes as Interfacial Materials for Soft Metal Conductors and Electronics; and more. Presents a comprehensive theory/simulation section that will be valuable for all readers Includes chapters not only on the biological applications of polymer brushes but also on biological systems that resemble polymer brushes on flat surfaces Addresses applications in coatings, friction, sensors, microelectromechanical systems, and biomaterials Devotes particular attention to the functional aspects of hybrid nanomaterials employing polymer brushes as functional units Polymer and Biopolymer Brushes: Fundamentals and Applications in Materials is aimed at both graduate students and researchers new to this subject as well as scientists already engaged in the study and development of polymer brushes.

Highlighting dynamic developments in polymer synthesis, this book focuses on the chemical techniques to synthesize and characterize biomedically relevant polymers and macromolecules. • Aids researchers developing polymers and materials for biomedical applications • Describes biopolymers from a synthetic perspective, which other similar books do not do • Covers areas that include: cationically-charged macromolecules, pseudo-peptides, polydrugs and prodrugs, controlled radical polymerization, self-assembly, polycondensates, and polymers for surface modification

This book on biopolymers offers a comprehensive source for biomaterial professionals. It covers all elementary topics related to the properties of biopolymers, the production, and processing of biopolymers, applications of biopolymers, examples of biopolymers, and the future of biopolymers. Edited by experts in the field, the book highlights international professionals’ longstanding experiences and addresses the requirements of practitioners and newcomers in this field in finding a solution to their problems. The book brings together several natural polymers, their extraction/production, and physio-chemical features. The topics covered in this book are biopolymers from renewable sources, marine prokaryotes, soy protein and humus oils, biopolymer recycling, chemical modifications, and specific properties. The book also focuses on the potential and diverse applications of biogenic and bio-derived polymers. The content includes industrial applications of natural polymeric molecules and applications in key areas such as material, biomedical, sensing, packaging, biomedicine, and biotechnology, and tissue engineering applications are discussed in detail. The objective of this book is to fill the gap between the researchers working in the laboratory to cutting-edge technological applications in related industries. This book will be a very valuable reference material for graduates and post-graduate students, academic researchers, professionals, research scholars, and scientists, and for anyone who has a flavor for doing biomaterial research. The books are designed to serve as a bridge between undergraduate textbooks in biochemistry and professional literature. The book provides universal perspectives for an emerging field where classical polymer science blends with molecular biology with highlights on recent advances.

A comprehensive theoretical ebook in the field of soft matter and biological science. This Ebook contains most recent advances in theory and simulations of artificial knee joint.

CONTENTS: Preface; Particle boards based on rice husk; Stabilisation of polymers with natural antioxidants; Mechanical performance of composites based on ethylene vinyl-acetate (eva) matrix with powdered in filler; Prediction of mechanical behaviour of hips/pp blends from solubility parameters; Bio-damages of materials. Adhesion of microorganisms on materials surface; Intensification of dust removal process of complex aerohydrodynamic research and the effectiveness of arresting dispersed particles for barbotage -- rotation; Application of a model based on consecutive reactions to polymer degradation; Transport of water as structurally sensitive process characterising morphology of biodegradable polymer systems; Retention Volumes of organic substances on the ester phases; Clay filled rigid polyurethane foams; Kinetics of bimolecular radicals decay in different polymeric matrixes; Mechanism of generation of stable nitrogen-containing radicals in the presence of nitrogen oxides; Hard and soft approaches to analysis of kinetic data; Free-radical mechanisms of formation of polysaccharides radiation destruction products; Generalisation of effects of solvent polymer interaction by means of linear multi-parametric equations; Index.

The present ebook covers the mathematical modeling and numerical simulations of polyelectrolyte brush bilayers under shear motion. The similar conditions could be found in mammalian knee joints. The new findings which is described in the last chapter shows that polymer brush bilayers are useful in lubrication exclusively in the presence of hydrodynamic interactions between monomers. This reveals the significance of interstitial water in knee joint.

This is the third edition of the book which contains ten chapters and it covers my research about polymer brush bilayers under shear. The chapter ten is devoted to polymer brush bilayers under non-equilibrium shear inversion which is very important in studying mammalian synovial joint behavior. In this chapter, it is revealed that the hydrodynamic interactions produce mechanical instabilities in the system while adding electrostatic interactions removes those mechanical instabilities.

Specifically dedicated to polymer and biopolymer systems, Polymer Adhesion, Friction, and Lubrication guides readers to the scratch, wear, and lubrication properties of polymers and the engineering applications, from biomedical research to automotive engineering. Author Hongbo Zeng details different experimental and theoretical methods used to probe static and dynamic properties of polymer materials and biomacromolecular systems. Topics include the use of atomic force microscopy (AFM) to analyze nanotribology, polymer thin films and brushes, nanoparticles, rubber and tire technology, synovial joint lubrication, adhesion in paper products, bioMEMS, and electrorheological fluids.

Explore this one-stop resource for reversible addition-fragmentation chain transfer polymerization from a leading voice in chemistry RAFT Polymerization: Methods, Synthesis and Applications delivers a comprehensive and insightful analysis of reversible addition-fragmentation chain transfer polymerization (RAFT) and its applications to fields as diverse as material science, industrial chemistry, and medicine. This one-stop resource offers readers a detailed synopsis of the current state of RAFT polymerization. This text will inspire further research and continue the drive to an ever-increasing range of applications by synthesizing and explaining the more central existing literature on RAFT polymerization. It contains a beginner’s guide on how to do a RAFT polymerization before moving on to much more advanced techniques and concepts, like the kinetics and mechanisms of the RAFT process. The distinguished editors have also included resources covering the four major classes of RAFT agents and recent developments in processes for initiating RAFT polymerization. Readers will also benefit from the inclusion of: A thorough introduction to the mechanisms, theory, and mathematical modeling of RAFT Explorations of RAFT agent design and synthesis, dithioesters, dithiobenzoates, trithiocarbonates, xanthates, dithiocarbamates, macromonomer RAFT, and RAFT copolymerization Discussions of a variety of RAFT architectures, including multiblocks, combs, hyperbranched polymers, and stars Treatments of end group transformation, cationic RAFT, high-throughput RAFT, and RAFT in continuous flow An examination of sequence defined polymers by RAFT Perfect for organic chemists, polymer chemists, and materials scientists, RAFT Polymerization: Methods, Synthesis and Applications will also earn a place in the libraries of chemical engineers seeking a one-stop reference for this method of controlled radical polymerization with a wide range of applications in multiple areas.

Patterned polymer brushes are used in biological applications to enhance cell function and to achieve selective cell growth. These patterned surfaces have a variety of applications, including cell sheet harvesting and tissue engineering. This work describes creation of chemical, topological, and responsive patterns on glass by sequential surface-initiated polymerization of poly(N-isopropylacrylamide)-co-(2-hydroxyethyl methacrylate) (pNIPAM-co-HEMA) and subsequent use of UV lithography to pattern the surface with pNIPAM. The cell adhesion peptide, RGD, is then immobilized on the surface of the copolymer pHEMA via DSC-coupling to spatially enhance cell adhesion properties. By culturing cells at 37 degrees celsius, cells selectively grow on DSC-activated pNIPAM-co-HEMA and not on the block copolymer pNIPAM due to its non-fouling properties at thicknesses greater than 20nm. Selective cell growth of NIH3T3, a mouse embryonic fibroblast cell line, is demonstrated on pNIPAM-co-HEMA/pNIPAM patterns of different dimensions. By lowering cell culture temperatures below the lower critical solution temperature (LCST) we can take advantage of the functionality of pHEMA's hydroxyl group and the thermoresponsive property of pNIPAM in order to detach patterned cell sheets detach from pNIPAM-co-HEMA surface. Thus, we have created a single polymer brush platform that provides both positive and negative tone patterns for cell growth, as well as incorporating thermoresponsive polymers to fine tune surface properties and enable selective detachment of cell sheets, as well as facile modification of non-fouling regions via common and robust DSC-coupling for use in cell sheet engineering applications.