The Carcinogenic Effects Of Polycyclic Aromatic Hydrocarbons

The Carcinogenic Effects Of Polycyclic Aromatic Hydrocarbons
Author :
Publisher : World Scientific
Total Pages : 514
Release :
ISBN-10 : 9781783260874
ISBN-13 : 1783260874
Rating : 4/5 (74 Downloads)

Synopsis The Carcinogenic Effects Of Polycyclic Aromatic Hydrocarbons by : Andreas Luch

This book provides an overview on the molecular mode of action of carcinogenic polycyclic aromatic hydrocarbons (PAHs). PAHs are by-products arising from incomplete combustion of organic matter that are frequently released into our environment, and thus are ubiquitously detectable. Many PAHs are strong carcinogens in rodent bioassays and have been linked to increased incidences of various types of cancer in humans. The present book covers all aspects of PAH-induced carcinogenesis; it is a collection of articles written by some of the most recognizable PAH researchers, reviewing the present knowledge in this field. The topics include: exposure to and biomonitoring of PAHs in the human population; metabolic activation of PAHs; genotoxicity and repair of PAH-induced DNA damage; and factors modulating individual susceptibility to the deleterious effects of PAHs.

Polycyclic Hydrocarbons and Carcinogenesis

Polycyclic Hydrocarbons and Carcinogenesis
Author :
Publisher :
Total Pages : 424
Release :
ISBN-10 : UOM:39015018288301
ISBN-13 :
Rating : 4/5 (01 Downloads)

Synopsis Polycyclic Hydrocarbons and Carcinogenesis by : Ronald G. Harvey

Good,No Highlights,No Markup,all pages are intact, Slight Shelfwear,may have the corners slightly dented, may have slight color changes/slightly damaged spine.

Polycyclic Aromatic Hydrocarbons

Polycyclic Aromatic Hydrocarbons
Author :
Publisher : CUP Archive
Total Pages : 428
Release :
ISBN-10 : 0521364582
ISBN-13 : 9780521364584
Rating : 4/5 (82 Downloads)

Synopsis Polycyclic Aromatic Hydrocarbons by : Ronald G. Harvey

This 1991 volume was the first to review the chemical properties of the carcinogenic polycyclic aromatic hydrocarbons.

Environmental Carcinogens

Environmental Carcinogens
Author :
Publisher : CRC Press
Total Pages : 376
Release :
ISBN-10 : 9781351088657
ISBN-13 : 1351088653
Rating : 4/5 (57 Downloads)

Synopsis Environmental Carcinogens by : G. Grimmer

The present survey comprises today‘s knowledge of environmental pollution in particular of the atmosphere by PAH and of the biological effects of this class of substance, putting special emphasis on their carcinogenic activity. The research data and conclusions derived therefrom are meant to assist the government of the Federal Republic of Germany in determining an air quality standard.

Bitumens and Bitumen Emissions, and Some N- and S-heterocyclic Polycyclic Aromatic Hydrocarbons

Bitumens and Bitumen Emissions, and Some N- and S-heterocyclic Polycyclic Aromatic Hydrocarbons
Author :
Publisher : World Health Organization
Total Pages : 364
Release :
ISBN-10 : UCR:31210023277963
ISBN-13 :
Rating : 4/5 (63 Downloads)

Synopsis Bitumens and Bitumen Emissions, and Some N- and S-heterocyclic Polycyclic Aromatic Hydrocarbons by : IARC Working Group on the Evaluation of Carcinogenic Risks to Humans

This volume of the IARC Monographs provides evaluations of the carcinogenicity of bitumens and their emissions, the N-heterocyclic polycyclic aromatic hydrocarbons benz[a]acridine, benz[c]acridine, dibenz[a,h]acridine, dibenz[a,j]acridine, dibenz[c,h]acridine, carbazole and 7H-dibenzo[c,g]carbazole, as well as the S-hetrocyclic polycyclic aromatic hydrocarbons benzo[b]naphtho[2,1-d]thiophene and dibenzothiophene. Bitumens are produced by distillation of crude oil during petroleum refining, and also occur naturally. Bitumens can be divided into six broad classes, according to their physical properties and specifications required for different applications. The major use (about 80%) of bitumens is for road paving; other uses include roofing, waterproofing, sealing and painting. The term "bitumen" should not be confused with "asphalt", which refers to the mixture of bitumen (4-10% by weight), small stones, sand and filler used for road paving. Bitumens are complex mixtures that contain a large number of organic chemical compounds. Application of bitumens may generate emissions (fumes and vapours) that may contain, among volatile and non-volatile compounds, a number of known or probable carcinogens. An IARC Monographs Working Group reviewed epidemiological evidence, animal bioassays, and mechanistic and other relevant data to reach conclusions as to the carcinogenic hazard to humans of various occupations that entail exposure to bitumens and bitumen emissions, including road paving, roofing, and application of mastic asphalt, and to various heterocyclic polycyclic aromatic compounds.

WHO Guidelines for Indoor Air Quality

WHO Guidelines for Indoor Air Quality
Author :
Publisher : World Health Organization
Total Pages : 488
Release :
ISBN-10 : UCBK:C105261333
ISBN-13 :
Rating : 4/5 (33 Downloads)

Synopsis WHO Guidelines for Indoor Air Quality by :

This book presents WHO guidelines for the protection of public health from risks due to a number of chemicals commonly present in indoor air. The substances considered in this review, i.e. benzene, carbon monoxide, formaldehyde, naphthalene, nitrogen dioxide, polycyclic aromatic hydrocarbons (especially benzo[a]pyrene), radon, trichloroethylene and tetrachloroethylene, have indoor sources, are known in respect of their hazardousness to health and are often found indoors in concentrations of health concern. The guidelines are targeted at public health professionals involved in preventing health risks of environmental exposures, as well as specialists and authorities involved in the design and use of buildings, indoor materials and products. They provide a scientific basis for legally enforceable standards.

Polycyclic Hydrocarbons

Polycyclic Hydrocarbons
Author :
Publisher : Springer Science & Business Media
Total Pages : 516
Release :
ISBN-10 : 9783662016657
ISBN-13 : 3662016656
Rating : 4/5 (57 Downloads)

Synopsis Polycyclic Hydrocarbons by : Eric Clar

Polycyclic hydrocarbons are of interest in many fields of science: theoretical chemistry, physical chemistry, organic chemistry, dyestuff chemistry and biology. With regard to the latter, I am indebted to Dr. Regina Schoental of the Medical Research Council for the review in this present work of carcinogenesis by polycyclic hydrocarbons. This book is designed to present the facts in a simple and clear order and to derive empirical rules from them, but it does not present a com prehensive theory about polycyclic hydrocarbons. An attempt is made instead to extend classical symbolism into modern structural chemistry. Thus extensive use is made of Robinson's aromatic sextet, which is applied in an uncompromising and strict way. This quasi-classical attempt is encouraged further by such completely unexpected dis coveries as those of Dewar benzene and of the electronic asymmetry of formally symmetric hydrocarbons. How difficult it is to break away from any established way of thinking has been admirably expressed by Kekule ("Organische Chemie", 1861, Part 1, page 4, translated from the German): "All our ideas are based, to an extent much greater than we ordinarily believe, on those of our predecessors. Our accumulated experience, the notions of which our training has accustomed us to, of whatever kind they have been, influence the course of our thoughts far more than we are willing to admit; only too frequently the following of our regularly used, well trodden way of thinking leads us to overlook the simplest of correlations.

Metabolism of Polycyclic Aromatic Hydrocarbons in the Aquatic Environment

Metabolism of Polycyclic Aromatic Hydrocarbons in the Aquatic Environment
Author :
Publisher : CRC Press
Total Pages : 360
Release :
ISBN-10 : 0849368448
ISBN-13 : 9780849368448
Rating : 4/5 (48 Downloads)

Synopsis Metabolism of Polycyclic Aromatic Hydrocarbons in the Aquatic Environment by : Usha Varanasi

This book shows how the biological transport, bioaccumulation, disposition, and toxicity of polycyclic aromatic hydrocarbons (PAH) in the aquatic environment are influenced by the ability or inability of organisms to metabolize these environmental pollutants. Written by leading scientists in the fields of PAH metabolism and toxicity in both aquatic and mammalian systems, this book discusses recent advances in the areas of PAH biogeochemistry and bioaccumulation, microbial degradation, enzymes of activation, and detoxication, metabolism of PAH, and laboratory and field studies on carcinogenic/toxic effects. Additionally, important similarities and differences in metabolism of PAH by aquatic and terrestrial organisms are featured. The discussion of bioavailability, metabolism, and subsequent toxic effects should aid in the assessment of the ecological consequences of PAH in the aquatic environment.

How Tobacco Smoke Causes Disease

How Tobacco Smoke Causes Disease
Author :
Publisher :
Total Pages : 728
Release :
ISBN-10 : UCSD:31822037817723
ISBN-13 :
Rating : 4/5 (23 Downloads)

Synopsis How Tobacco Smoke Causes Disease by : United States. Public Health Service. Office of the Surgeon General

This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.