The Hypothalamus-Pituitary-Adrenal Axis

The Hypothalamus-Pituitary-Adrenal Axis
Author :
Publisher : Elsevier
Total Pages : 413
Release :
ISBN-10 : 9780080559360
ISBN-13 : 0080559360
Rating : 4/5 (60 Downloads)

Synopsis The Hypothalamus-Pituitary-Adrenal Axis by :

The hypothalamic-pituitary-adrenal axis controls reactions to stress and regulates various body processes such as digestion, the immune system, mood and sexuality, and energy usage. This volume focuses on the role it plays in the immune system and provides substantive experimental and clinical data to support current understanding in the field, and potential applications of this knowledge in the treatment of disease. - Evidence presented in this book suggests that the nervous, endocrine, and immune systems form the Neuroendoimmune Supersystem, which integrates all the biological functions of higher organisms both in health and disease for their entire life cycle - Contributors include both the scientists who initiated the work on the HPA axis and on the autonomic nervous system, and those who joined the field later

Pituitary Function and Immunity

Pituitary Function and Immunity
Author :
Publisher : CRC Press
Total Pages : 350
Release :
ISBN-10 : 9781000013313
ISBN-13 : 1000013316
Rating : 4/5 (13 Downloads)

Synopsis Pituitary Function and Immunity by : Istvan Berczi

First published in 1986, the influence of hormones secreted or regulated by the pituitary gland on the immune system is examined in detail, including discussions of adrenocorticotropic hormone, glucocorticoids, catecholamines, growth hormone, insulin, prolactin, gonadotropins, sex steroid hormones, and thyroid hormones. The relative importance of various hormones in immunoregulation is considered, and evidence for interaction between the immune and neurohormonal systems is presented. The possible effects of hormonal immunomodulation in reproduction, infections and parasitic disease, autoimmu-nity, and cancer are examined. This comprehensive reference serves both basic and clinical researchers and practitioners in immunology, microbiology, endocrinology, reproduction biology, neurology, oncology, psychology, medicine, and veterinary medicine.

Anatomy and Physiology

Anatomy and Physiology
Author :
Publisher :
Total Pages : 0
Release :
ISBN-10 : 1947172808
ISBN-13 : 9781947172807
Rating : 4/5 (08 Downloads)

Synopsis Anatomy and Physiology by : J. Gordon Betts

An Introduction to Neuroendocrinology

An Introduction to Neuroendocrinology
Author :
Publisher : Cambridge University Press
Total Pages : 434
Release :
ISBN-10 : 0521426650
ISBN-13 : 9780521426657
Rating : 4/5 (50 Downloads)

Synopsis An Introduction to Neuroendocrinology by : Richard E. Brown

This book is designed as an introductory text in neuroendocrinology; the study of the interaction between the brain and endocrine system and the influence of this on behaviour. The endocrine glands, pituitary gland and hypothalamus and their interactions and hormones are discussed. The action of steroid and thyroid hormone receptors and the regulation of target cell response to hormones is examined. The function of neuropeptides is discussed with respect to the neuroendocrine system and behaviour. The neuroimmune system and lymphokines are described and the interaction between the neuroendocrine and neuroimmune systems discussed. Finally, methods for studying hormonal influences on behaviour are outlined. Each chapter has review and essay questions designed for advanced students and honours or graduate students with a background in neuroscience, respectively.

Inflammation, 4 Volume Set

Inflammation, 4 Volume Set
Author :
Publisher : John Wiley & Sons
Total Pages : 1818
Release :
ISBN-10 : 9783527338993
ISBN-13 : 3527338993
Rating : 4/5 (93 Downloads)

Synopsis Inflammation, 4 Volume Set by : Jean-Marc Cavaillon

Dieses Fachbuch erläutert die molekularen Grundlagen von Entzündungen, spannt den Bogen zu Infektionskrankheiten und den Zusammenhang zwischen Entzündungen und chronischen Erkrankungen, behandelt abschließend den Heilungsprozess und zeigt Therapiemöglichkeiten.

Handbook on Immunosenescence

Handbook on Immunosenescence
Author :
Publisher : Springer Science & Business Media
Total Pages : 1693
Release :
ISBN-10 : 9781402090639
ISBN-13 : 1402090633
Rating : 4/5 (39 Downloads)

Synopsis Handbook on Immunosenescence by : Tamas Fulop

This authoritative handbook covers all aspects of immunosenescence, with contributions from experts in the research and clinical areas. It examines methods and models for studying immunosenescence; genetics; mechanisms including receptors and signal transduction; clinical relevance in disease states including infections, autoimmunity, cancer, metabolic syndrome, neurodegenerative diseases, frailty and osteoporosis; and much more.

Growth Hormone Deficiency in Adults

Growth Hormone Deficiency in Adults
Author :
Publisher : Karger Medical and Scientific Publishers
Total Pages : 241
Release :
ISBN-10 : 9783805579926
ISBN-13 : 3805579926
Rating : 4/5 (26 Downloads)

Synopsis Growth Hormone Deficiency in Adults by : Jens O. L. Jørgensen

It has been known for over 40 years that GH-deficient-children benefit from replacement with the hormone. But GH, essential for longitudinal growth, also plays a role after completion of final height. With the introduction of biosynthetic human GH 20 years ago, the use of GH was no longer restricted to severe growth retardation in hypopituitary children. This book will take the reader behind the myths of GH and into the real world of clinical endocrinology. The contributions stem from recognized clinicians and scientists who have been working in the field for decades. The contents encompass traditional end points of GH therapy such as body composition, bone biology and physical performance. Attention is also devoted to diagnostic aspects and side effects. Additional features range from clinical epidemiology to quality of life, and novel areas such as the impact of traumatic brain injury on pituitary function are also covered. The present volume of Frontiers of Hormone Research is essential reading for health care professionals interested in clinical endocrinology and GH.

Enkephalins and Endorphins

Enkephalins and Endorphins
Author :
Publisher : Springer Science & Business Media
Total Pages : 440
Release :
ISBN-10 : 9781489905574
ISBN-13 : 148990557X
Rating : 4/5 (74 Downloads)

Synopsis Enkephalins and Endorphins by : R.E. Faith

Is this a time for a sleeping giant to rise? We have known since study of the lymphocyte and plasma cells really began in earnest in the early 1940's that the pituitary adrenal axis under intimate control of the hypothalamus could influence immunological functions profoundly. We have also known for at least 20 years in my recollection that female sex hor mones can maximize certain immunity functions while male sex hormones tend to suppress many immunological reactions. The thyroid hormones accelerate antibody production while at the same time sp~eding up de gradation of antibodies and immunoglobulins and thyroidectomy decreases the rate of antibody production. Further, much evidence has accumulated indicating that the brain, yes even the mind, can influence in significant ways susceptibility to infections, cancers and to development of a variety of autoimmune diseases. More than 20 years ago, my colleagues and I convinced ourselves, if no one else, that hypnosis can exert major in fluences on the effector limb of the classical atopic allergic reactions. We showed with Aaron Papermaster that the Prausnitz-Kustner reaction may be greatly inhibited, indeed largely controlled, by post-hypnotic suggestion. And it was not even necessary for us to publish our discovery because scientists in John Humphrey's laboratory at Mill Hill Research Center in London had beaten us to the punch. They described hypnotic control of both the PK reaction and delayed allergic reactions to tuberculin by hypnosis.

Endoscopic Endonasal Transsphenoidal Surgery

Endoscopic Endonasal Transsphenoidal Surgery
Author :
Publisher : Springer Science & Business Media
Total Pages : 228
Release :
ISBN-10 : 3211009728
ISBN-13 : 9783211009727
Rating : 4/5 (28 Downloads)

Synopsis Endoscopic Endonasal Transsphenoidal Surgery by : Enrico de Divitiis

Currently, surgical management provides the definitive treatment of choice for most pituitary adenomas, craniopharyngiomas and meningiomas of the sellar region. The elegant minimally invasive transnasal endoscopic approach to the sella turcica and the anterior skull base has added a new dimension of versatility to pituitary surgery and can be adapted to many lesions in the region. In this multi-author book with numerous color illustrations the main aspects of the endonasal endoscopic approach to the skull base are presented, starting with a clear description of the endoscopic anatomy, the panoramic view afforded by the endoscope and the development of effective instruments and adjuncts. After the diagnostic studies, the strictly surgical features are considered in detail. The standard technique is described and particular aspects are treated, including the new extended approaches to the cavernous sinus, spheno-ethmoid planum and clival regions. The book stresses the importance of teamwork and has been produced by one of the pioneering groups in the field of endoscopic approaches to the pituitary. It is a useful guide primarily for neurosurgeons and sinonasal endoscopic surgeons but also for other specialists involved in the diagnosis and treatment of skull base lesions.

Endocrine and Metabolic Late Effects in Cancer Survivors

Endocrine and Metabolic Late Effects in Cancer Survivors
Author :
Publisher : Karger Medical and Scientific Publishers
Total Pages : 169
Release :
ISBN-10 : 9783318067910
ISBN-13 : 3318067911
Rating : 4/5 (10 Downloads)

Synopsis Endocrine and Metabolic Late Effects in Cancer Survivors by : Francesco Felicetti (Oncologist)

This book analyzes in detail all aspects related to endocrine and metabolic late effects observed in patients treated for cancer, both in childhood and adulthood. The chapters focusing on the possible pathogenic mechanisms of late effects (i.e., premature aging and chronic inflammation) and on bone health in cancer survivors are particularly interesting and innovative. The volume also deals with hypothalamic-pituitary, thyroid and gonadal disorders, including infertility and how to prevent it. Finally, the relationship between metabolic alterations and cardiovascular diseases in cancer survivors is addressed. Thanks to advances in cancer treatment and supportive care, the five-year survival rate of cancer patients is constantly increasing. However, this undisputable success of medicine has a flip side: the late adverse effects of anticancer therapies. Pediatric oncologists were the first to cope with late complications of treatments, but today also adult oncologists and onco-hematologists recognize the relevance of this issue. Even though late effects observed in cancer survivors can affect any organ or system, endocrine and metabolic dysfunctions are the most frequently reported. Endocrine complications rarely influence life expectancy of cancer survivors, but they can significantly impact morbidity and quality of life. Among endocrine adverse effects, severe hypothalamic damage may be considered the most harmful in survivors, leading to morbid obesity, propensity to metabolic syndrome and cardiovascular disease. This book aims to disseminate the knowledge about endocrine and metabolic adverse effects of cancer therapies and about survivorship care. Since the number of cancer survivors is steadily growing in the general population, this publication is intended not only for endocrinologists but also for oncologists, onco-hematologists, internists, pediatric specialists in those areas and general practitioners, with the aim to better counsel and monitor cancer survivors.