This is a motley document, the product of many, presented for what it is. Fondly conceived as another Flexner report, it lacked a Flexner to produce it. The excitement of planning by varied committees was not always maintained through execution; communication, necessarily difficult, was strained by im portant changes in operating staff; questions were forgotten by the time answers became available; too much was undertaken with inadequate experi ence and funds (large though the support seemed) ; multiple purposes and distributed responsibility caused confusion and delay; the inevitable and evi table hazards of an extended undertaking exacted their full toll. As a result, the report is seriously late in appearing, and it lacks important portions of the anticipated perspectives along time and across disciplines. But high devotion and hard labor have been poured into the mold, and the finished creation is not without merit. The Survey did pioneer in formulating a study of a profession, and its struggles have supplied both guidance and warning to many followers. It did amass great chunks of new data, collate older information, and make interpretations of the whole which have been put to use long before this report was completed. And it did catalyze much other successful activity, especially in the area of education, by the American Physiological Society and its sister organizations and by agents of other in terests, from mathematics to medical schools.

This unified modeling textbook for students of biomedical engineering provides a complete course text on the foundations, theory and practice of modeling and simulation in physiology and medicine. It is dedicated to the needs of biomedical engineering and clinical students, supported by applied BME applications and examples. Developed for biomedical engineering and related courses: speaks to BME students at a level and in a language appropriate to their needs, with an interdisciplinary clinical/engineering approach, quantitative basis, and many applied examples to enhance learning Delivers a quantitative approach to modeling and also covers simulation: the perfect foundation text for studies across BME and medicine Extensive case studies and engineering applications from BME, plus end-of-chapter exercises