This issue of the Clinics in Laboratory Medicine on “Pharmacogenomics is being edited by Drs. Roland Valdes and Kristen Reynolds and will cover a wide variety of topics, including but not limited to, fundamentals of pharmacology, a review of pharmacogenetics guidelines, pharmacogenetic testing in pain management, pharmacogenetics of pain management, clinical and economic impact of pharmacogenetic genotyping analysis, exosome analysis in lab medicine, and implementation of pharmacogenetics in developing countries.

In this issue of Clinics in Laboratory Medicine, guest editor Dr. Gregory Tsongalis brings his considerable expertise to Current Topics in Molecular Diagnostics and Precision Medicine. Top experts in the field cover key topics such as syndromic and point-of-care molecular testing; building evidence for clinical use of pharmacogenomics and reimbursement for testing; precision medicine using pharmacogenomic panel-testing; and more. - Contains 12 relevant, practice-oriented topics including next-generation sequencing approaches to predicting antimicrobial susceptibility testing results; the role of the human gutome on chronic disease: a review of the microbiome and nutrigenomics; blood group genotyping; review of SARS-CoV-2 antigen and antibody testing in diagnosis and community surveillance; and more. - Provides in-depth clinical reviews on current topics in molecular diagnostics and precision medicine, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

This issue of Clinics in Laboratory Medicine, edited by Dr. Martin Bluth, will cover a wide array of topics related to drug testing and toxicology. Experts will discuss common drugs in analgesia, toxicology techniques, errors and interferences in toxicology testing, toxicology considerations in pain and addiction medicine, toxicology in reproductive endocrinology, forensic toxicology, and toxicology in emergency medicine, among others.

This updated issue of Clinics in Laboratory Medicine, edited by Martin H. Bluth, will focus on Molecular Pathology. Topics include, but are not limited to, The Impact of Molecular Pathology on the Practice of Pathology; Molecular pathology techniques; Clinical Implication of MicroRNAs in Molecular Pathology; Diagnostic Molecular Microbiology; Molecular Pathology in Transfusion Medicine; Molecular Diagnosis of Hematopoietic Neoplasms; Molecular Diagnostics in Colorectal Carcinoma; Molecular Diagnostics in the Neoplasms of Small Intestine and Appendix; Molecular Diagnostics in Esophageal and Gastric Neoplasms; Molecular Diagnostics in the Neoplasms of the Pancreas, Liver, Gall Bladder, and Extrahepatic Biliary Tract; Current Applications of Molecular Genetic Technologies to the Diagnosis and Treatment of Cutaneous Melanocytic Neoplasms; Breast Carcinoma; and Gynecologic Cancers.

This issue of Clinics in Laboratory Medicine, edited by Drs. Nahed Ismail, A. William Pasculle, and James Snyder, will cover a wide variety of Emerging Pathogens. Topics covered in this issue include, but are not limited to West Nile Virus; Zika Virus; Ebola and Marburg Heamorrhagic Fever; Rift Valley Fever; Carbapenem Resistant Enterobacteriacae; Closteridium Difficuile; and Chikungunya, among others.

This issue of Clinics in Laboratory Medicine, titled Toxicology Testing, includes the following topics; Progress in Clinical Toxicology Testing, The Prescription Drug Abuse Epidemic, Substance Abuse Among Healthcare Professionals, Pain Management Drug Testing, Ethanol Biomarkers, Newly-emerging Drugs of Abuse, Synthetic Cannabinoids, Synthetic Cathenones, Immunoassay Methodology in Drugs-of-abuse Testing, Toxicology Testing in Alternative Specimen Matrices, Principles and Procedures in Postmortem Toxicology, and Pharmacogenetics and the Future of Toxicology Testing. Advances in toxicology testing are paving the way for major improvements in the way scientists evaluate health risks posed by toxic chemicals. Toxicity tests help scientists better understand how the human body carries out normal functions that are key to maintaining health. Therefore, this topic is important to the field of Laboratory Medicine.

This issue of Surgical Pathology Clinics, edited by Dr. Laura C. Collins, will focus on Breast Pathology. Topics include, but are not limited to: Core needle biopsy of the breast, Mucinous Lesions of the Breast: Pragmatic approach to fibroepithelial lesions; Lymph node inclusions; Differential diagnosis of benign spindle cell lesions of the breast; Ancillary Prognostic and Predictive Testing in Breast Cancer; Lesions of the Low Grade Breast Neoplasia Pathway; Genotype-Phenotype Correlation in Breast Neoplasia; Lobular Carcinoma in Situ; and Processing and Reporting of Breast Specimens in the Neoadjuvant Setting.

Pharmacogenomics is the basis of personalized medicine, which is said to be the medicine of the future. Understanding genetic variation in drug and alcohol response is vital for professionals working in rehabilitation programs. The same principles that are applicable for therapeutic drugs are also applicable for drugs of abuse. Pharmacogenomics can

This issue of Clinics in Laboratory Medicine entitled “Risk, Error and Uncertainty: Laboratory Quality Management in the Age of Metrology will be guest edited by Sten Westgard, James Westgard, and David Armbruster. The issue will cover a broad range of topics related to management in the laboratory including but not limited to: Metrology Perspectives; Biologic Variation Approach to Daily Laboratory; Clinical Outcome Approach to Goal Setting; Six Sigma Quality Management System; Traceability and Comparability; MU, Risk, and Sigma-metrics at Sunway; and Quality Indicators for the Total Testing Process, among others.

Advances in the technology used in personalized medicine and increased applications for clinical use have created a need for this expansion and revision of Kewal K. Jain’s Textbook of Personalized Medicine. As the first definitive work on this topic, this book reviews the fundamentals and development of personalized medicine and subsequent adoptions of the concepts by the biopharmaceutical industry and the medical profession. It also discusses examples of applications in key therapeutic areas, as well as ethical and regulatory issues, providing a concise and comprehensive source of reference for those involved in healthcare management, planning and politics. Algorithms are included as a guide to those involved in the management of important diseases where decision-making is involved due to the multiple choices available. Textbook of Personalized Medicine, Second Edition will serve as a convenient source of information for physicians, scientists, decision makers in the biopharmaceutical and healthcare industries and interested members of the public.