This issue of PET Clinics focuses on PET Imaging in Pediatric Patients and is edited by Drs. Hongming Zhuang and Abass Alavi. Articles will include: Promising New PET tracers in the evaluation of pediatric disease; F-DOPA PET/CT in the management of congenital hyperinsulinism; Emerging roles of PET/MRI in pediatric hospital; Roles of FDG PET/CT in the management of posttransplant lymphoproliferative disease in pediatric patient; FDG-PET/CT in the management of pediatric lymphoma; Preparation and logistic consideration in performing PET/CT and PET/MRI in pediatric patients; PET/CT in the evaluation of FUO and infectious/inflammatory disease in pediatric patients; Roles of PET/CT in the evaluation of neuroblastoma; Potential Roles of Total Body Imaging in Pediatric Diseases and Disorders; PET/CT in the Management of Pediatric Sarcomas; Pediatric Cardiac PET Imaging; Dosimetry between PET/CT and PET/MRI: Implications in Pediatric Imaging; Essential Role of Global Disease Assessment in Assessing Systemic Disorders, and more!

This issue provides a complete update on PET imaging of lymphoma, starting with a clinical assessment of lymphoma and the role of medical imaging. The role of structural imaging in lymphoma is then discussed. From a Nuclear Medicine perspective, FDG-PET in lymphoma is reviewed, as is the role of FDG-PET in pediatric lymphoma. Next, the role of non-FDG tracers in lymphoma is reviewed. Other articles cover the role of fMRI and optical imaging in lymphoma, the role of diffusion-weighted MRI in lymphoma, FDG-PET in personalization of therapy in patients with lymphoma, and PET and radiation oncology in lymphoma.

Currently there is no shortage of challenges and opportunities for PET instrumentation and quantitative imaging techniques. Molecular imaging technologies are leading to a revolutionary paradigm shift in health care and clinical practice. This issue reviews recent advances in PET instrumentation as well as volume correction strategies and strategies for motion tracking and correction, scatter compensation techniques, and attenuation correction techniques.

The technique for successfully completing a PET procedure is complex and involves a knowledge of physics, pharmacy, anatomy, physiology, and the disease process; applying PET scanning to children is even more challenging and technically demanding. One cannot simply adopt the approach used for adults but instead must receive specialized training in order to master pediatric PET procedures. This one-of-a-kind, interdisciplinary book is one of the first practical guides to imaging children with PET. The text opens with a section that focuses on practical and technical issues of pediatric PET imaging, including radiation dose and sedation. Principles of operation, instrumentation, and nuclear medicine regulations are also discussed. Subsequent sections cover the clinical applications of PET in pediatrics. With contributions from leading international authorities in the field, each chapter is heavily illustrated and provides the reader with extensive coverage of the essentials of clinical PET studies in oncology and neurology, which standout as key areas for PET imaging in pediatrics.

This issue of MRI Clinics of North America focuses on Pediatric MR Imaging, and is edited by Dr. Edward Y. Lee. Articles will include: MRI Evaluation of Pediatric Neck Masses: Review and Update; MRI of Lungs and Airways in Children: Past and Present; Pediatric Mediastinal Masses: Role of MRI As a Problem-Solving Tool; Pediatric Cardiac MRI: Practical Preoperative Assessment; Hepatobiliary MRI in Children: Up-To-Date Imaging Techniques and Findings; Pediatric Renal Neoplasms: MRI-Based Practical Diagnostic Approach; MRI Evaluation of Inflammatory Bowel Disease in Children: Where Are We Now in 2018?; MRI Evaluation of Pediatric Genital Disorders: MR Technology Overview and Interpretation; Pediatric Sport-related Injuries: An Imaging Overview for Current and Future Daily Practice; MRI of Pediatric Musculoskeletal Tumors: Recent Advances and Clinical Applications; MRI Evaluation of Pediatric Lymphatics: Overview of Techniques and Imaging Findings; PET-MRI: Current Updates on Pediatric Applications; Tales from the Night: Emergency MRI in Pediatric Patients after Hours; and more!

PET/CT holds great promise for the management of many types of infection and inflammation. This issue discusses many of these uses, starting with arthroplasty-associated infection. FDG PET/CT also has utility in inflammatory bowel disease. This issue also discusses the utilization of FDG PET and PET/CT in the evaluation of diabetic foot, and in monitoring therapeutic effect in patients without malignancy. PET/CT is reviewed regarding its use in patients with sarcoidosis or IgG4 disease. Also covered is the application of FDG PET/CT in detecting the source of fever of unknown origin. Artherosclerosis and vasculitis can be assessed by PET/CT and FDG PET/CT can also be used in the management of severe infection in patients with malignancies. Finally, the issue discusses the use of PET and PET/CT in the evaluation of osteomyelitis.

This issue of PET Clinics focuses on PET/MRI: Clinical Applications, and is edited by Drs. Drew Torigian and Andreas Kjaer. Articles will include: PET/MRI in Prostate Cancer; PET/MRI in Vascular Disease; PET/MRI in Lymphoma; PET/MRI in Head and Neck Cancer; PET/MRI in Brain Disease; PET/MR in Cancers of GI Tract; PET/MRI in Gynecologic Cancer; Clinical PET/MRI Systems and Patient Workflow; PET/MRI in Heart Disease; PET/MR in Breast Cancer and Lung Cancer; PET/MRI in Musculoskeletal Disorders; PET/MRI in Pediatric Oncology; Clinical PET/MRI: Future Perspectives; and more!

The use of F-18 NaF PET/CT versus conventional bone scanning in the assessment of benign and malignant disorders has many advantages, which are discussed at length in this issue.Imaging of a variety of benign and malignant bone diseases is discussed, including the assessment of disease and the monitoring of patient response to therapy. Imaging in pediatric patients is also discussed.

PET/CT is an integral part of the evaluation of patients who have head and neck cancer. In this issue, the state of the art in PET/CT imaging is discussed. The issue starts with an overview of FDG-PET/CT, PET and MRI for normal anatomy, including pitfalls and artifacts. This topic is followed by a review of FDG-PET/CT for initial and subsequent therapy evaluation; progressing to PET and MRI. Other articles discuss SUV as a prognostic factor in head and neck squamous cell carcinoma, PET in head and neck cancer radiotherapy treatment planning, PET in decision making for neck dissection after radiation treatment, and newer methods for improving yield from FDG-PET imaging for accurate staging, determining tumor biology, and assessing prognosis. The issue focuses on some of the most cutting-edge applications, such as new tracers PET in head and neck squamous cell carcinoma (including FLT and hypoxia imaging). PET scans in thyroid cancer is also discussed.

Dr. Wheeler is providing a much needed update on the topic of critical care medicine for the pediatrician. He organized the issue to give a full overview on those topics that most pertinent to practicing clinicians. His authors are top experts in their fields, and they are writing clinical reviews devoted to The Evolving Model of Pediatric Critical Care, The High Reliability Pediatric Intensive Care Unit, Telemedicine and the Pediatric Intensive Care Unit, Resuscitation and Stabilization of the Critically Ill Child, Monitoring and Management of Acute Respiratory Failure, Monitoring and Management of Shock, Cardiac Intensive Care, Monitoring and Management of Acute Kidney Injury, Critical Care of the Bone Marrow Transplant Patient, Neurocritical Care, Ethics and End-of-Life Care, Delirium in the Pediatric Intensive Care Unit, and Family-centered Care in the Pediatric Intensive Care Unit.