In this issue, guest editors bring their considerable expertise to this important topic. Provides in-depth reviews on the latest updates in the field, providing actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews.

With collaboration from Consulting Editor Dr. Norman Gitlin, Dr. Rosenthal has created an issue that provides current clinical information on the diagnosis and treatment of liver diseases in children. Expert authors from top institutions have contributed review articles on the following topics: Biliary atresia; Alagille Syndrome; Hepatitis B & C in Children; NAFLD/NASH; Bile acid defects; Progressive Familial Intrahepatic Cholestasis; Autoimmune hepatitis/PSC/Overlap syndrome; Portal hypertension/Cirrhosis in Children; Alpha-1-antitrypsin deficiency; Hepatic tumors; Acute Liver Failure; and Liver transplantation in Children. Readers will come away with the information they need to make clinical decisions that will improve patient outcomes.

Pediatric Gastroenterology, An Issue of Pediatric Clinics of North America, E-Book

The fourth edition of this authoritative text covers every aspect of liver disease affecting infants, children and adolescents. As in the previous editions, it offers an integrative approach to the science and clinical practice of pediatric hepatology and charts the substantial progress in understanding and treating these diseases. All of the chapters are written by international experts and address the unique pathophysiology, manifestations and management of these disorders. This edition of the landmark text features extended coverage of viral hepatitis, metabolic liver disease, fatty liver disease and liver transplantation, including a new chapter on post-transplant care and outcomes. All of the chapters have been updated to reflect changing epidemiology and recent advances in molecular medicine and genomics. With the continued evolution of pediatric hepatology as a discipline, this text remains an essential reference for all physicians involved in the care of children with liver disease.

In this issue, guest editors bring their considerable expertise to this important topic.

This was an important Symposium in a rapidly developing field of interest. It was designed to draw attention to areas which have been neglected in standard hepatology textbooks and to review areas of controversy. It was also meant to help bridge the communication gap between hepatologists'caring for children and adults as well as between some areas of clinical and basic research. The Symposium was a substantial success. Unfortunately two of the twenty participants did not deliver a manuscript. The result is a publication which is late and which is not as complete as it should be. For this lateness and incompleteness the editors apolo gize most sincerely--especially to those participants who delivered their manuscripts on time but even to those who delivered their manu scripts late. perhaps the most noteworthy feature of this publication is the fact that material presented in May 1980 is by no means out of date. Apart from the section on Viral Hepatitis, one of the most rapidly evolving fields of medicine, the context of the Symposium remains disturbingly current. The neglect continues, the controversies remain. We hope that this publication will help draw investigators into liver research, provide a useful point of reference for· those in the field and stand as a monument to editors past, present and future, who have chased, are chasing and will chase manuscripts in vain.

Diseases of the Liver in Children: Evaluation and Management provides a comprehensive, state-of-the art review of pediatric liver disease, with a practical approach useful for the primary care provider or general gastroenterologist. With an emphasis on tables and images, this book serves as a reference for understanding basic hepatic processes and the significance of laboratory findings. It also discusses the state of the art of diagnosis and treatment of diseases that affect the pediatric liver. The text captures the key elements of treatment and monitoring important for the primary care provider partnering in the care of these patients with pediatric hepatologists. The current state of transplantation and other surgical approaches are also discussed. The importance of aggressive bowel rehabilitation in the prevention of end-stage total parenteral nutrition-induced liver disease is also covered. Written by experts in their fields and including the most up to date clinical information, Diseases of the Liver in Children: Evaluation and Management serves as a very useful resource for physicians.

This atlas is a problem-based practical book presenting clinical scenarios for children with liver disease. Each chapter demonstrates the clinical presentation, diagnostic pathway, therapy and outcome. Rich in illustrations of clinical pictures, tables and graphs of data, each chapter also contains pictures of radiology, histopathology and other important diagnostic information. This book outlines a multidisciplinary approach to diagnosis and management of pediatric liver disease and covers diseases encountered in South Asia, the Far East and the Middle East. This work will appeal to a wide readership, from trainees in hepatology and Paediatric Gastroenterology to General Paediatricians and Allied Health Professionals including Dieticians, Nurses, Transplant Co-Ordinators.

In collaboration with Consulting Editor, Dr. Norman Gitlin, Dr. Steven Flamm has put together another great update for the hepatology consult. Articles are submitted by expert author and in the format of the clinical review article, provide timely data for diagnosis and treatment. Specific areas addressed include the following: Management of esophageal and gastric varices; Severe thrombocytopenia in chronic liver disease and new management approaches; Pathology in chronic liver disease; Alpha 1 antitrypsin disease and chronic liver disease in adults; Evaluation of management of Budd-Chiari; HBV reactivation with immunosuppressive therapy; Homeopathic products and hepatotoxicity; New uses of TIPS; Dermatologic manifestations of chronic liver disease; Acute on chronic liver failure; Cholangiocarcinoma; Diagnosis and management of hepatic adenoma and focal nodular hyperplasia; Emerging data about the microbiome in chronic liver disease; and Acute viral hepatitis aside from HAV, HBV, and HCV. Readers will come away with the information they need to improve patient outcomes.