The American Joint Committee on Cancer's Cancer Staging Manual is used by physicians throughout the world to diagnose cancer and determine the extent to which cancer has progressed. All of the TNM staging information included in this Sixth Edition is uniform between the AJCC (American Joint Committee on Cancer) and the UICC (International Union Against Cancer). In addition to the information found in the Handbook, the Manual provides standardized data forms for each anatomic site, which can be utilized as permanent patient records, enabling clinicians and cancer research scientists to maintain consistency in evaluating the efficacy of diagnosis and treatment. The CD-ROM packaged with each Manual contains printable copies of each of the book’s 45 Staging Forms.

This book provides a comprehensive and up-to-date review of all aspects of childhood Acute Lymphoblastic Leukemia, from basic biology to supportive care. It offers new insights into the genetic pre-disposition to the condition and discusses how response to early therapy and its basic biology are utilized to develop new prognostic stratification systems and target therapy. Readers will learn about current treatment and outcomes, such as immunotherapy and targeted therapy approaches. Supportive care and management of the condition in resource poor countries are also discussed in detail. This is an indispensable guide for research and laboratory scientists, pediatric hematologists as well as specialist nurses involved in the care of childhood leukemia.

The second, fully updated edition of this book applies and contextualizes up-to-date information on pediatric surgery for low and middle-income countries (LMICs). The book is organized in general anatomic and thematic sections within pediatric surgery, such as urology, oncology, orthopedics and gastroenterology and includes chapters addressing the unique challenges and approaches for pediatric surgery in low-resource settings. Each chapter has dual authorship LMIC author providing context-specific insights and authors from high-income countries (HICs) contributing experience from well-resourced settings. Written in a reader-friendly format, this book has a uniform structure in each chapter, with introduction, demographics, etiology, pathophysiology, clinical presentations, investigations, management, outcome, prevention, ethics, evidence-based surgery and references. This comprehensive volume fills the gap between up-to-date pediatric surgical scholarship and knowledge developed and applied in HICs, and the practical needs of practitioners in low-resource settings. This is an indispensable guide for postgraduate surgical trainees in Africa and other LMICs as well as general surgeons practicing in Africa and other LMICs, who need to care surgically for children.

Seidel's Guide to Physical Examination is a comprehensive textbook of physical examination, history-taking, and health assessment with a unique emphasis on differential diagnosis and variations across the lifespan. The book conveys a uniquely compassionate, patient-centered approach to physical examination with a strong evidence-based foundation. Evidence-Based Practice in Physical Examination boxes supply you with current data on the most effective techniques for delivering quality patient care. Clinical Pearls lend insights and clinical expertise to help you develop clinical judgment skills. Functional Assessment boxes present a more holistic approach to patient care that extends beyond the physical exam to patients’ functional ability. Staying Well boxes focus you on patient wellness and health promotion. Risk Factor boxes provide opportunities for patient teaching or genetic testing for a variety of conditions. Differential diagnosis content offers you an understanding of how disease presentations vary and specific information for how to make diagnoses from similar abnormal findings. Abnormal Findings tables equip you with a quick, illustrated reference that allows for comparisons of various abnormalities along with key symptoms and underlying pathophysiology. Sample Documentation boxes clarify appropriate professional language for the process of recording patient assessment data. NEW! Advance Practice Skills highlighted throughout text makes identification and reference easier for students. NEW! Updated content throughout provides you with cutting-edge research and a strong evidence-based approach to care. NEW! Vital Signs and Pain Assessment Chapter groups important, foundational tasks together for easy reference in one location. NEW! Improve readability ensures content remains clear, straightforward, and easy to understand. NEW! Updated illustrations and photographs enhances visual appeal and clarifies anatomic concepts and exam techniques.