This book provides comprehensive coverage of current topics in idiopathic scoliosis (IS). A three-dimensional deformity of the spine, the condition is characterized by lateral curvature combined with vertebral rotation. The primary lesion, however, lies in the median sagittal plane, taking the form of a lordosis. Although the clinical manifestations of scoliosis have been well documented, its cause and pathogenesis have not yet been determined. Research into what causes IS has focused on the structural elements of the spine, spinal musculature, collagenous structures, the endocrine system, the central nervous system, and genetics. Results of these studies have brought about a new perception of IS epiphenomena, but the main cause of IS remains unknown. Recently, several investigators have produced new hypotheses regarding the cause of IS using the developing techniques of genetics, biochemistry, and neurology. This book is a review of the various causative factors thus far proposed for IS and an introduction to the directions in which research is heading to determine the primary cause of IS.

Covers the anatomy, etiology, and natural history of scoliosis - from patient evaluation and an algorithm for treatment to pulmonary function after surgical treatment and the use of instruments to evaluate surgical treatment. This new monograph focuses on the most common form of scoliosis occurring otherwise normal adolescents, affecting spinal alignment, growth, and function.

Developmental genetic studies of the spine and linkage and family-based association studies have led to recent advances in understanding the genetic etiology of idiopathic, neuromuscular, and congenital forms of scoliosis. The book is written by leaders in genetic and developmental research on scoliosis and developmental studies of the spine.

Based on over a decade of research and observation conducted by the members of the Harms Study Group and other spinal deformity experts from around the world, this must-have clinical reference provides focused coverage of the most current evaluation and treatment guidelines for idiopathic scoliosis. It draws on case studies to guide readers through specific surgical and nonoperative approaches to the multiple types of adolescent idiopathic spinal deformity, including practical information on the rationale for each approach, techniques, and results. Features: In-depth information culled from vast clinical data of world-renowned experts in the Harms Study Group Curve assessment and treatment recommendations listed by curve type and pattern - Comprehensive discussion of pathogenesis and epidemiology, osteobiologics for spinal fusion, anesthesia for scoliosis surgery, surgical complications, and more Chapters on key treatment decisions, such as the selection of fusion levels, that teach readers how to critically address clinical questions More than 600 high-quality illustrations, including numerous full-color clinical photographs, detailed line drawings, and complementary high-resolution radiographs This state-of-the-art text is ideal for orthopaedic surgeons, neurosurgeons, and spine fellows, and is an invaluable companion for any practitioner involved in the surgical and nonsurgical care of patients with spinal deformity.

While most spine deformities such as scoliosis, kyphosis, and lordosis are idiopathic, muscular dystrophy, cerebral palsy, spinal cord tumors and lesions are associated with more severe curve progression. Bracing typically does not prevent progression of spinal curves, and surgery is necessary for these patients. Neuromuscular Spine Deformity by Amer F. Samdani et al is the most comprehensive book on this topic to date, detailing the latest surgical techniques for a wide range of common to rare neuromuscular pathologies, in 27 well-illustrated chapters. The comprehensive content derives from the authors' collective years of hands-on expertise, evidence-based knowledge from the literature, and multicenter scoliosis studies performed by the prestigious Harms Study Group, a worldwide research-based association of spine surgeons. The text begins with discussion of preoperative evaluation, nonoperative management, and surgical considerations such as anesthesia, neuromonitoring, and estimated blood loss. Section two highlights pathology-specific surgical interventions, while sections three and four provide clinical pearls on a wide array of surgical techniques, complications, and patient outcomes. Key Highlights Disease-related challenges including dislocated hips, hyperlordotic/hyperkyphotic spine in cerebral palsy, myelomeningocele-related myelodysplasia and spine deformity, Duchenne's muscular dystrophy, and spinal muscular atrophy Guidance on assessing the sagittal profile preoperatively and executing it intraoperatively in patients with spinal cord injury Multiple options for fixation including the new sacral alar iliac screw approach for sacropelvic fixation and correction of pelvic obliquity Postoperative issues including ICU management, incidence and management of early and late wound infection, instrumentation failure, junctional kyphosis, and cervical extension Health-related quality of life outcomes in pediatric patients with cerebral palsy who have undergone scoliosis surgery This state-of-the-art resource is essential reading for orthopaedic surgeons, neurosurgeons, and trainees in these specialties. It is also a must-have reference for academic programs and institutional departments specializing in pediatric spine pathologies.

Spinal disorders are among the most common medical conditions with significant impact on health related quality of life, use of health care resources and socio-economic costs. This is an easily readable teaching tool focusing on fundamentals and basic principles and provides a homogeneous syllabus with a consistent didactic strategy. The chosen didactic concept highlights and repeats core messages throughout the chapters. This textbook, with its appealing layout, will inspire and stimulate the reader for the study of spinal disorders.

This book presents a wide-ranging series of illustrative clinical cases that cover the main pathologies and areas of interest in diagnostic and therapeutic neuroradiology. The aim is to enable the reader to learn important lessons from real cases that exemplify the caseload and capabilities of a large, modern neuroradiology department. The cases are presented in a quiz format. For each one, the first page documents clinical and imaging findings, followed by questions concerning these findings, differential diagnosis, and other aspects. On the second page, the answers are provided, with concise explanation and discussion. Attention is also drawn to the relevant available literature. Most of the cases derive from the Department of Neuroradiology at the University Hospital Center of Porto (Portugal), which is staffed by a large multidisciplinary team providing cutting-edge services. In addition, some cases from other centers have been included to ensure wider representation of experience. The book will be of particular value for residents and fellows in neuroradiology, radiology, neurology, and neurosurgery.

Written and edited by leading international authorities in the field, this book provides an in-depth review of knowledge of tuberculosis of the central nervous system, with emphasis on clinical, diagnostics, and therapeutic features. Tuberculosis, one of the most lethal diseases in human history, still poses a serious threat in the world together with economic and social problems, although a great progress in the fight against this infectious disease in the last century. It covers the full range of tuberculosis of central nervous system and the chapters are organized into six sections: (1) the cranial; (2) the spinal; and (3) the peripheral portions of the nervous system; followed by (4) a section on the laboratory studies in tuberculosis; (5) a section on medical and surgical therapy; and (6) further insights into tuberculosis. This comprehensive reference book will be an ideal source for neurosurgeons, neurologists and specialists upon infectious diseases seeking both basic and more sophisticated information and surgical procedures relating to the complications associated with tuberculosis involving the spine, brain and peripheral nerves.

Chest wall deformities encompass a variety of congenital and acquired pathologies that affect the pediatric and the adult population. This comprehensive work offers detailed state of the art information on the changing paradigms in ultrastructural evaluation, diagnosis, clinical investigation, and treatment and reflects the shift towards conservative and minimally invasive treatment options. The combination of concise descriptions and high-quality images will provide the reader with a clear understanding of all relevant concepts. Diagnostic and imaging modalities are analysed in depth, and surgical procedures are explained step by step with the aid of clear, informative illustrations. Experts in the management of chest wall deformities from all over the world have contributed their experiences and approaches, making this a unique textbook in the field and an ideal reference work for clinicians and surgeons.​

This book series is an official publication of the G.I.S. (Grupo Italiano Scoliosi - Italian Scoliosis Research Group), an association of highly specialized orthopaedic surgeons which was founded about ten years ago with the aim of enhancing knowledge and research in the basic science, diagnosis and therapy of vertebral diseases. Gathering the most remarkable papers presented at the annual meeting of the G.I.S., the series represents the best of current practice and research in the field of Spinal Pathology throughout the whole of Italy. From the foreword by R.B. Winter: "The Italian Group for the Study of Scoliosis is to be commended for its systematic "attack" on subjects related to vertebral deformity. In this volume, the subject is adult scoliosis. The papers herein presented cluster around three themes: (1) the natural history of scoliosis in adults, (2) the surgical treatment of scoliosis with particular reference to the quality of correction balanced against the complications of the surgery, and (3) the benefits of treatment, particularly in regards to pain and respira tory function."