This book constitutes the refereed proceedings of the 4th International Workshop on Patch-Based Techniques in Medical Images, Patch-MI 2018, held in conjunction with MICCAI 2018, in Granada, Spain, in September 2018. The 15 full papers presented were carefully reviewed and selected from 17 submissions. The papers are organized in the following topical sections: Image Denoising ̧ Image Registration and Matching, Image Classification and Detection, Brain Image Analysis, and Retinal Image Analysis.

This book constitutes the thoroughly refereed post-workshop proceedings of the First International Workshop on Patch-based Techniques in Medical Images, Patch-MI 2015, which was held in conjunction with MICCAI 2015, in Munich, Germany, in October 2015. The 25 full papers presented in this volume were carefully reviewed and selected from 35 submissions. The topics covered are such as image segmentation of anatomical structures or lesions; image enhancement; computer-aided prognostic and diagnostic; multi-modality fusion; mono and multi modal image synthesis; image retrieval; dynamic, functional physiologic and anatomic imaging; super-pixel/voxel in medical image analysis; sparse dictionary learning and sparse coding; analysis of 2D, 2D+t, 3D, 3D+t, 4D, and 4D+t data.

This book constitutes the refereed proceedings of the Third International Workshop on Patch-Based Techniques in Medical Images, Patch-MI 2017, which was held in conjunction with MICCAI 2017, in Quebec City, QC, Canada, in September 2017. The 18 regular papers presented in this volume were carefully reviewed and selected from 26 submissions. The papers are organized in topical sections on multi-atlas segmentation; segmentation; Alzheimer’s disease; reconstruction, denoising, super-resolution; tumor, lesion; and classification, retrival.

This book constitutes the refereed proceedings of the Second International Workshop on Patch-Based Techniques in Medical Images, Patch-MI 2016, which was held in conjunction with MICCAI 2016, in Athens, Greece, in October 2016. The 17 regular papers presented in this volume were carefully reviewed and selected from 25 submissions. The main aim of the Patch-MI 2016 workshop is to promote methodological advances within the medical imaging field, with various applications in image segmentation, image denoising, image super-resolution, computer-aided diagnosis, image registration, abnormality detection, and image synthesis.

Level set methods are numerical techniques which offer remarkably powerful tools for understanding, analyzing, and computing interface motion in a host of settings. When used for medical imaging analysis and segmentation, the function assigns a label to each pixel or voxel and optimality is defined based on desired imaging properties. This often includes a detection step to extract specific objects via segmentation. This allows for the segmentation and analysis problem to be formulated and solved in a principled way based on well-established mathematical theories. Level set method is a great tool for modeling time varying medical images and enhancement of numerical computations.

This book constitutes the refereed proceedings of the 5th International Workshop on Machine Learning in Medical Imaging, MLMI 2014, held in conjunction with the International Conference on Medical Image Computing and Computer Assisted Intervention, MICCAI 2014, in Cambridge, MA, USA, in September 2014. The 40 contributions included in this volume were carefully reviewed and selected from 70 submissions. They focus on major trends and challenges in the area of machine learning in medical imaging and aim to identify new cutting-edge techniques and their use in medical imaging.

The three-volume set LNCS 10433, 10434, and 10435 constitutes the refereed proceedings of the 20th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2017, held inQuebec City, Canada, in September 2017. The 255 revised full papers presented were carefully reviewed and selected from 800 submissions in a two-phase review process. The papers have been organized in the following topical sections: Part I: atlas and surface-based techniques; shape and patch-based techniques; registration techniques, functional imaging, connectivity, and brain parcellation; diffusion magnetic resonance imaging (dMRI) and tensor/fiber processing; and image segmentation and modelling. Part II: optical imaging; airway and vessel analysis; motion and cardiac analysis; tumor processing; planning and simulation for medical interventions; interventional imaging and navigation; and medical image computing. Part III: feature extraction and classification techniques; and machine learning in medical image computing.

This book constitutes the thoroughly refereed post-workshop proceedings of the International Workshop on Medical Computer Vision, MCV 2010, held in Beijing, China, in September 2010 as a satellite event of the 13th International Conference on Medical Image Computing and Computer Assisted Intervention, MICCAI 2010. The 10 revised full papers and 11 revised poster papers presented were carefully reviewed and selected from 38 initial submissions. The papers explore the use of modern image recognition technology in tasks such as semantic anatomy parsing, automatic segmentation and quantification, anomaly detection and categorization, data harvesting, semantic navigation and visualization, data organization and clustering, and general-purpose automatic understanding of medical images.

The task of object localization in medical images is a corner stone of automatic image processing and a prerequisite for other medical imaging tasks. In this thesis, we present a general framework for the automatic detection and localization of spatially correlated key points in medical images based on a conditional random field (CRF). The problem of selecting suitable potential functions (knowledge sources) and defining a reasonable graph topology w.r.t. the dataset is automated by our proposed data-driven CRF optimization. We show how our fairly simple setup can be applied to different medical datasets involving different image dimensionalities (i.e., 2D and 3D), image modalities (i.e., X-ray, CT, MRI) and target objects ranging from 2 to 102 distinct key points by automatically adapting the CRF to the dataset. While the used general "default" configuration represents an easy to transfer setup, it already outperforms other state-of-the-art methods on three out of four datasets. By slightly gearing the proposed approach to the fourth dataset, we further illustrate that the approach is capable of reaching state-of-the-art performance of highly sophisticated and data-specific deep-learning-based approaches. Additionally, we suggest and evaluate solutions for common problems of graph-based approaches such as the reduced search space and thus the potential exclusion of the correct solution, better handling of spatial outliers using latent variables and the incorporation of invariant higher order potential functions. Each extension is evaluated in detail and the whole method is additionally compared to a rivaling convolutional-neural-network-based approach on a hard problem (i.e., the localization of many locally similar repetitive target key points) in terms of exploiting the spatial correlation. Finally, we illustrate how follow-up tasks, segmentation in this case, may benefit from a correct localization by reaching state-of-the-art performance using off-the-shelve methods in combination with our proposed method.

Deep Learning for Medical Image Analysis, Second Edition is a great learning resource for academic and industry researchers and graduate students taking courses on machine learning and deep learning for computer vision and medical image computing and analysis. Deep learning provides exciting solutions for medical image analysis problems and is a key method for future applications. This book gives a clear understanding of the principles and methods of neural network and deep learning concepts, showing how the algorithms that integrate deep learning as a core component are applied to medical image detection, segmentation, registration, and computer-aided analysis.· Covers common research problems in medical image analysis and their challenges · Describes the latest deep learning methods and the theories behind approaches for medical image analysis · Teaches how algorithms are applied to a broad range of application areas including cardiac, neural and functional, colonoscopy, OCTA applications and model assessment · Includes a Foreword written by Nicholas Ayache