This book provides a practical overview of osteoporosis for the wide spectrum of clinicians that might encounter the osteoporotic patient. Concise and well-structured chapters examine the public health importance of the condition, the current treatment gap, how to identify individuals who would benefit from treatment, bone turnover and how this can be modified by osteoporosis therapies, adjuvant lifestyle modification, the calcium and vitamin D story, antiresorptive therapies, anabolic therapies, emerging therapies, adherence and compliance with therapy and the perception of fracture risk. Osteoporosis Treatment: A Clinical Overview meets the need for a book that improves awareness of this major public health problem and possible therapeutic approaches. Primary care physicians, endocrinologists, rheumatologists, orthopaedic surgeons and those providing specialist care for the elderly will all benefit from this highly accessible and informative guide to treating osteoporosis.

Providing a comprehensive review of short-and long-term adverse events of both antiresorptive and anabolic drugs, this practical guide updates the clinician on the pathophysiology of osteoporosis and the principles behind our present and future pharmaceuticals. Leading practitioners in the field examine all current literature and data regarding the duration and safety of these therapies, with recommendations for clinicians on decision-making and best practices for osteoporosis patients. An overview of the pathophysiology and epidemiology of osteoporosis and discussion of both anabolic and antiresorptive drugs is followed by fracture risk assessment and an examination of treatment failures. Next, a number of chapters are dedicated to the diagnosis, presentation and management of atypical femur fractures and osteonecrosis of the jaw (ONJ), each of which are significant patient concerns when using these osteoporosis treatments. The introduction and utilization of drug holidays is also discussed, as well as the long-term outlook for management of osteoporotic patients. Written and edited by experts in the field, The Duration and Safety of Osteoporosis Treatment is a balanced resource for researchers, practitioners and policy-makers alike for clinical decision-making and patient care.

Since the publication of the first edition, the U.S. Surgeon General released the first-ever report on bone health and osteoporosis in October 2004. This report focuses even more attention on the devastating impact osteoporosis has on millions of lives. According to the National Osteoporosis Foundation, 2 million American men have osteoporosis, and another 12 million are at risk for this disease. Yet despite the large number of men affected, the lack of awareness by doctors and their patients puts men at a higher risk that the condition may go undiagnosed and untreated. It is estimated that one-fifth to one-third of all hip fractures occur in men. This second edition brings on board John Bilezikian and Dirk Vanderschueren as editors with Eric Orwoll. The table of contents is more than doubling with 58 planned chapters. The format is larger – 8.5 x 11. This edition of Osteoporosis in Men brings together even more eminent investigators and clinicians to interpret developments in this growing field, and describe state-of-the-art research as well as practical approaches to diagnosis, prevention and therapy. - Brings together more eminent investigators and clinicians to interpret developments in this growing field - Describes state-of-the-art research as well as practical approaches to diagnosis, prevention and therapy - There is no book on the market that covers osteoporosis in men as comprehensively as this book

This book provides a review of the most recent data on osteoporosis and bone health, presenting a vision of diagnosis and management for the year 2021 and beyond. It covers all pertinent aspects of bone health including diagnosis, fracture prevention, optimized practice, impaired orthostasis, and falls. The book examines recent developments in therapeutics, including goal-directed therapy, individualizing therapy, sequential and combined therapies, pharmaceuticals, and anabolic vs. antiresorptive therapy. In addition, it provides an in-depth overview of osteoporosis and bone health in complex patients, covering Duchene dystrophy, renal failure, periodontal diseases, and steroid-induced osteoporosis as well as considerations for pediatric populations and men. New Horizons in Osteoporosis Management is an essential resource for physicians and related professionals, residents, fellows, graduate students and nurses in rheumatology, endocrinology, radiology, pediatrics, primary care, and internal medicine.

Osteoporosis is the most common bone disease and is associated with pathological fractures that can lead to significant morbidity. It represents an economic burden to the health care system, directly linked to an ageing population. Guidelines on osteoporosis prevention have been published but these do not provide the required specialised knowledge

Marcus and Feldman's Osteoporosis, Fifth Edition, is the most comprehensive, authoritative reference on this disease. Led by a new editorial team, this fifth edition offers critical information on reproductive and hormonal risk factors, new therapeutics, ethnicity, nutrition, therapeutics, management and economics, comprising a tremendous wealth of knowledge in a single source not found elsewhere. Written by renowned experts in the field, this two-volume reference is a must-have for biomedical researchers, research clinicians, fellows, academic and medical libraries, and any company involved in osteoporosis drug research and development. - Summarizes the latest research in bone biology and translational applications in a range of new therapeutic agents, including essential updates on therapeutic uses of calcium, vitamin D, SERMS, bisphosphonates, parathyroid hormone, and new therapeutic agents - Recognizes the critical importance of new signaling pathways for bone health, including Wnt, OPG and RANK, of interest to both researchers who study bone biology and clinicians who treat osteoporosis - Offers new insights into osteoporosis associated with menopause, pre-menopause, chronic kidney disease, diabetes, HIV and other immune disorders

Osteoporosis is a global threat because it can impact every human being as they age. In this new edition, the authors point out the enormous scale of the problem in terms of human suffering, morbidity and mortality on the one hand, and the astronomical national costs on the other. Written in an easy-to-read style, this book updates physicians on the current knowledge about bone structure, physiology and pathology, with an emphasis on the diagnosis, therapy and prevention of osteoporosis. Its purpose is to educate members of the medical profession about this widespread and potentially disabling disease, while providing information on related current evidence-based medicine. The book covers everything from basic physiology to osteoporosis diagnosis, including utility of specialized tests and current treatment recommendations, and will provide the primary care physician with sound medical knowledge in the prevention and management of osteoporosis. It is up-beat and optimistic, with a touch of humor; it is scientifically based but provides easy-to-follow guidelines for lifelong maintenance of skeletal structure and function. Osteoporosis is preventable if doctors want it to be, and every doctor can contribute. Bone is every doctor's and every body's business.

Completely revised and updated, and utilizing the most current evidence and practice guidelines for the treatment of osteoporosis, this comprehensive third edition discusses the basic aspects of bone metabolism, the pathophysiology of osteoporosis, current diagnostic techniques and medical treatment strategies. Osteoporosis is a common disorder that is prevalent in over 20 million Americans over the age of 60. One and a half million osteoporotic fractures occur in the United States every year, including 300,000 hip fractures. Mortality rates after hip fracture approach 25%, with another 50% of patients experiencing a major decrease in their prior level of independence and quality of life. Despite the wide prevalence and severe consequences of osteoporosis, it remains a disorder that is severely under-diagnosed and treated. In this context, specialists and primary care physicians alike are having increasing difficulty keeping up with the rapid changes to the field and incorporating these advances to clinical care. In the years since the last edition of this book was published, the osteoporosis field has changed drastically. In addition to revising and updating existing chapters and removing a few that are no longer as relevant, new chapters discuss an advanced understanding of the cellular and molecular mechanisms underlying the disorder, the introduction of new diagnostic imaging techniques, a more nuanced appreciation of the risks and benefits of osteoporosis therapies, and the introduction of two new classes of osteoporosis medications. Following the format of the second edition, and including helpful key points at the opening of each chapter, this text will present a comprehensive overview of both the basic and clinical concepts relating to each topic, when appropriate. Chapter authors were chosen based on their high level of expertise and leadership in the field. Taken together, this text should thus be of great interest to physicians of multiple specialties, allied health professionals, as well as basic and clinical researchers.

This practical guide presents the most up-to-date information on the application of non-pharmacological and physical therapeutic measures, either used independently or in combination with pharmacotherapy, for the management of osteoporosis. Pharmacotherapy remains the primary treatment for osteoporosis, but to improve the biomechanical competence of bone and improve quality of life, there needs to be more comprehensive management approach involving non-pharmacological methods. The book opens with a discussion of the diagnosis, pathophysiology, complications and consequences of osteoporosis. Exercise, nutrition, orthotics, and other rehabilitation measures such as whole body vibration and electrical muscle stimulation, each described in details in chapters of their own, have had a beneficial impact on fall and fracture prevention as well as recovery post-fracture. In addition, the application of acupuncture for pain management and movement-based mind-body therapies like tai chi and the Feldenkrais method are explored. Providing a description of independent and adjuvant techniques and practices for treatment and improving quality of life, Non-Pharmacological Management of Osteoporosis is an excellent resource for endocrinologists, bone specialists, physical therapists, occupational therapists and all clinical practitioners and staff working with osteoporosis patients.

This first-ever Surgeon General's Report on bone health and osteoporosis illustrates the large burden that bone disease places on our Nation and its citizens. Like other chronic diseases that disproportionately affect the elderly, the prevalence of bone disease and fractures is projected to increase markedly as the population ages. If these predictions come true, bone disease and fractures will have a tremendous negative impact on the future well-being of Americans. But as this report makes clear, they need not come true: by working together we can change the picture of aging in America. Osteoporosis, fractures, and other chronic diseases no longer should be thought of as an inevitable part of growing old. By focusing on prevention and lifestyle changes, including physical activity and nutrition, as well as early diagnosis and appropriate treatment, Americans can avoid much of the damaging impact of bone disease and other chronic diseases. This Surgeon General's Report brings together for the first time the scientific evidence related to the prevention, assessment, diagnosis, and treatment of bone disease. More importantly, it provides a framework for moving forward. The report will be another effective tool in educating Americans about how they can promote bone health throughout their lives. This first-ever Surgeon General's Report on bone health and osteoporosis provides much needed information on bone health, an often overlooked aspect of physical health. This report follows in the tradition of previous Surgeon Generals' reports by identifying the relevant scientific data, rigorously evaluating and summarizing the evidence, and determining conclusions.