Organic Chemistry Concepts And Applications For Medicinal Chemistry
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Author |
: Joseph E. Rice |
Publisher |
: Academic Press |
Total Pages |
: 219 |
Release |
: 2014-04-14 |
ISBN-10 |
: 9780128008324 |
ISBN-13 |
: 0128008326 |
Rating |
: 4/5 (24 Downloads) |
Synopsis Organic Chemistry Concepts and Applications for Medicinal Chemistry by : Joseph E. Rice
Organic Chemistry Concepts and Applications for Medicinal Chemistry provides a valuable refresher for understanding the relationship between chemical bonding and those molecular properties that help to determine medicinal activity. This book explores the basic aspects of structural organic chemistry without going into the various classes of reactions. Two medicinal chemistry concepts are also introduced: partition coefficients and the nomenclature of cyclic and polycyclic ring systems that comprise a large number of drug molecules. Given the systematic name of a drug, the reader is guided through the process of drawing an accurate chemical structure. By emphasizing the relationship between structure and properties, this book gives readers the connections to more fully comprehend, retain, apply, and build upon their organic chemistry background in further chemistry study, practice, and exams. - Focused approach to review those organic chemistry concepts that are most important for medicinal chemistry practice and understanding - Accessible content to refresh the reader's knowledge of bonding, structure, functional groups, stereochemistry, and more - Appropriate level of coverage for students in organic chemistry, medicinal chemistry, and related areas; individuals seeking content review for graduate and medical courses and exams; pharmaceutical patent attorneys; and chemists and scientists requiring a review of pertinent material
Author |
: Allan D. Headley |
Publisher |
: John Wiley & Sons |
Total Pages |
: 626 |
Release |
: 2020-01-02 |
ISBN-10 |
: 9781119504580 |
ISBN-13 |
: 1119504589 |
Rating |
: 4/5 (80 Downloads) |
Synopsis Organic Chemistry by : Allan D. Headley
Provides an in-depth study of organic compounds that bridges the gap between general and organic chemistry Organic Chemistry: Concepts and Applications presents a comprehensive review of organic compounds that is appropriate for a two-semester sophomore organic chemistry course. The text covers the fundamental concepts needed to understand organic chemistry and clearly shows how to apply the concepts of organic chemistry to problem-solving. In addition, the book highlights the relevance of organic chemistry to the environment, industry, and biological and medical sciences. The author includes multiple-choice questions similar to aptitude exams for professional schools, including the Medical College Admissions Test (MCAT) and Dental Aptitude Test (DAT) to help in the preparation for these important exams. Rather than categorize content information by functional groups, which often stresses memorization, this textbook instead divides the information into reaction types. This approach bridges the gap between general and organic chemistry and helps students develop a better understanding of the material. A manual of possible solutions for chapter problems for instructors and students is available in the supplementary websites. This important book: • Provides an in-depth study of organic compounds with division by reaction types that bridges the gap between general and organic chemistry • Covers the concepts needed to understand organic chemistry and teaches how to apply them for problem-solving • Puts a focus on the relevance of organic chemistry to the environment, industry, and biological and medical sciences • Includes multiple choice questions similar to aptitude exams for professional schools Written for students of organic chemistry, Organic Chemistry: Concepts and Applications is the comprehensive text that presents the material in clear terms and shows how to apply the concepts to problem solving.
Author |
: Thomas Haldane |
Publisher |
: |
Total Pages |
: 243 |
Release |
: 2018-02-26 |
ISBN-10 |
: 1632385864 |
ISBN-13 |
: 9781632385864 |
Rating |
: 4/5 (64 Downloads) |
Synopsis Medicinal Chemistry: Concepts and Applications by : Thomas Haldane
Medicinal chemistry studies the design and development of pharmaceutical drugs. It is a multi-disciplinary subject that combines pharmacology, synthetic organic chemistry, toxicology, molecular biology, etc. Discovery of newer pharmaceutical agents by studying existing drugs with pathological or biological targets is the main concern of this field. Performing clinical trials and assessing the effectiveness of drugs is another significant facet of medicinal chemistry. The topics covered in this extensive book deal with the core aspects of medicinal chemistry. It aims to equip students and experts with the advanced topics and upcoming concepts in this area.
Author |
: Saul Rowen |
Publisher |
: |
Total Pages |
: 242 |
Release |
: 2017-05-16 |
ISBN-10 |
: 1632385511 |
ISBN-13 |
: 9781632385512 |
Rating |
: 4/5 (11 Downloads) |
Synopsis Concepts and Applications of Organic Chemistry by : Saul Rowen
Since twentieth century, organic chemistry emerged and has been rapidly expanding throughout without deceleration in the progress of this field. Foundations of medicine and biotechnology are built on organic compounds. It is contributing to the research in medicinal chemistry, polymer chemistry, as well as several aspects of materials science. This book discusses the fundamentals and concentrates on the applications of organic chemistry. It presents the concepts and applications in a concise manner for a better understanding of the subject. Students, researchers, experts and all associated with organic chemistry will benefit alike from this book.
Author |
: Marc Harrold |
Publisher |
: ASHP |
Total Pages |
: 405 |
Release |
: 2013-01-18 |
ISBN-10 |
: 9781585283644 |
ISBN-13 |
: 1585283649 |
Rating |
: 4/5 (44 Downloads) |
Synopsis Basic Concepts in Medicinal Chemistry by : Marc Harrold
Medicinal chemistry is a complex topic. Written in an easy to follow and conversational style, Basic Concepts in Medicinal Chemistry focuses on the fundamental concepts that govern the discipline of medicinal chemistry as well as how and why these concepts are essential to therapeutic decisions. The book emphasizes functional group analysis and the basics of drug structure evaluation. In a systematic fashion, learn how to identify and evaluate the functional groups that comprise the structure of a drug molecule and their influences on solubility, absorption, acid/base character, binding interactions, and stereochemical orientation. Relevant Phase I and Phase II metabolic transformations are also discussed for each functional group. Key features include: • Discussions on the roles and characteristics of organic functional groups, including the identification of acidic and basic functional groups. • How to solve problems involving pH, pKa, and ionization; salts and solubility; drug binding interactions; stereochemistry; and drug metabolism. • Numerous examples and expanded discussions for complex concepts. • Therapeutic examples that link the importance of medicinal chemistry to pharmacy and healthcare practice. • An overview of structure activity relationships (SARs) and concepts that govern drug design. • Review questions and practice problems at the end of each chapter that allow readers to test their understanding, with the answers provided in an appendix. Whether you are just starting your education toward a career in a healthcare field or need to brush up on your organic chemistry concepts, this book is here to help you navigate medicinal chemistry. About the Authors Marc W. Harrold, BS, Pharm, PhD, is Professor of Medicinal Chemistry at the Mylan School of Pharmacy, Duquesne University, Pittsburgh, PA. Professor Harrold is the 2011 winner of the Omicron Delta Kappa "Teacher of the Year" award at Duquesne University. He is also the two-time winner of the "TOPS" (Teacher of the Pharmacy School) award at the Mylan School of Pharmacy. Robin M. Zavod, PhD, is Associate Professor for Pharmaceutical Sciences at the Chicago College of Pharmacy, Midwestern University, Downers Grove, IL, where she was awarded the 2012 Outstanding Faculty of the Year award. Professor Zavod also serves on the adjunct faculty for Elmhurst College and the Illinois Institute of Technology. She currently serves as Editor-in-Chief of the journal Currents in Pharmacy Teaching and Learning.
Author |
: James O. Schreck |
Publisher |
: |
Total Pages |
: 520 |
Release |
: 1975 |
ISBN-10 |
: OCLC:760964100 |
ISBN-13 |
: |
Rating |
: 4/5 (00 Downloads) |
Synopsis Organic Chemistry by : James O. Schreck
Author |
: Wei Zhang |
Publisher |
: John Wiley & Sons |
Total Pages |
: 769 |
Release |
: 2012-07-23 |
ISBN-10 |
: 9780470711514 |
ISBN-13 |
: 0470711515 |
Rating |
: 4/5 (14 Downloads) |
Synopsis Green Techniques for Organic Synthesis and Medicinal Chemistry by : Wei Zhang
Green chemistry is a new way of looking at organic synthesis and the design of drug molecules, offering important environmental and economic advantages over traditional synthetic processes. Pharmaceutical companies are increasingly turning to the principles of green chemistry in an effort to reduce waste, reduce costs and develop environmentally benign processes. Green Techniques for Organic Synthesis and Medicinal Chemistry presents an overview of the established and emerging techniques in green organic chemistry, highlighting their applications in medicinal chemistry. The book is divided into four parts: Introduction: Introduces the reader to the toxicology of organic chemicals,their environmental impact, and the concept of green chemistry. Green Catalysis: Covers a variety of green catalytic techniques including organocatalysis, supported catalysis, biocatalysis, fluorous catalysis, and catalytic direct C-H bond activation reactions. Green Synthetic Techniques: Presents a series of new techniques, assessing the green chemistry aspects and limitations (i.e. cost, equipment, expertise). Techniques include reactions in alternative solvents, atom economic multicomponent reactions, microwave and ultrasonic reactions, solid-supported synthesis, fluorous and ionic liquid-based recycling techniques, and flow reactors. Green Techniques in Pharmaceutical Industry: Covers applications of green chemistry concepts and special techniques for medicinal chemistry, including synthesis, analysis, separation, formulation, , and drug delivery. Process and business case studies are included to illustrate the applications in the pharmaceutical industry. Green Techniques for Organic Synthesis and Medicinal Chemistry is an essential resource on green chemistry technologies for academic researchers, R&D professionals and students working in organic chemistry and medicinal chemistry.
Author |
: Thomas L. Lemke |
Publisher |
: |
Total Pages |
: 156 |
Release |
: 1988 |
ISBN-10 |
: UOM:39015013200848 |
ISBN-13 |
: |
Rating |
: 4/5 (48 Downloads) |
Synopsis Review of Organic Functional Groups by : Thomas L. Lemke
Author |
: Paul M. Dewick |
Publisher |
: John Wiley & Sons |
Total Pages |
: 711 |
Release |
: 2013-03-20 |
ISBN-10 |
: 9781118681961 |
ISBN-13 |
: 1118681967 |
Rating |
: 4/5 (61 Downloads) |
Synopsis Essentials of Organic Chemistry by : Paul M. Dewick
Essentials of Organic Chemistry is an accessible introduction to the subject for students of Pharmacy, Medicinal Chemistry and Biological Chemistry. Designed to provide a thorough grounding in fundamental chemical principles, the book focuses on key elements of organic chemistry and carefully chosen material is illustrated with the extensive use of pharmaceutical and biochemical examples. In order to establish links and similarities the book places prominence on principles and deductive reasoning with cross-referencing. This informal text also places the main emphasis on understanding and predicting reactivity rather than synthetic methodology as well as utilising a mechanism based layout and featuring annotated schemes to reduce the need for textual explanations. * tailored specifically to the needs of students of Pharmacy Medical Chemistry and Biological Chemistry * numerous pharmaceutical and biochemical examples * mechanism based layout * focus on principles and deductive reasoning This will be an invaluable reference for students of Pharmacy Medicinal and Biological Chemistry.
Author |
: Francesca Hopkins |
Publisher |
: Murphy & Moore Publishing |
Total Pages |
: 245 |
Release |
: 2021-11-16 |
ISBN-10 |
: 1639874984 |
ISBN-13 |
: 9781639874989 |
Rating |
: 4/5 (84 Downloads) |
Synopsis Selected Topics in Organic Chemistry by : Francesca Hopkins
The branch of chemistry that includes the study of structures, properties, composition, reaction and preparation of organic compounds is known as organic chemistry. Organic compounds are covalently bonded carbon containing compounds including hydrogen, halogen and other elements. They are classified on the basis of functional groups, aliphatic groups, aromaticity and the size of molecule. Organic compounds are structurally diverse and form the functional and structural basis of all living beings and many commercial products. Organic chemistry is an umbrella science which overlaps organometallic chemistry, biochemistry, medicinal chemistry, materials science and polymer chemistry. Organic chemistry is applied in a large number of industries such as pharmaceutical industry, petroleum industry, and chemical industry. This book traces the progress of this field and highlights some of its key concepts and applications. The topics included in this book on organic chemistry are of utmost significance and bound to provide incredible insights to readers. It aims to serve as a resource guide for students and experts alike and contribute to the growth of the discipline.