"Full of gorgeous language and wild insights."—Nick Flynn Set in the beleaguered heart of Indiana’s opioid crisis, Brian Allen Carr’s timely and tender novel about a teen struggling to find his place in the world—and come up with $800 rent—is at once a moving rumination on the hopeful power of story and a harrowing insight into modern America. It is a book you won’t soon forget. Seventeen-year-old Riggle is living in rural Indiana with his uncle and uncle’s girlfriend after the death of his parents. Now his uncle is missing, probably on a drug binge. It’s Monday, and $800 in rent is due Friday. Riggle, who’s been suspended from school, has to either find his uncle or get the money together himself. His mission exposes him to a motley group of Opioid locals—encounters by turns perplexing, harrowing, and heartening. With empathy and insight, Carr explores what it’s like to be a high school kid in the age of Trump—a time of economic inequality, addiction, Confederate flags, and mass shootings. Through the voice of its unforgettable protagonist—charismatic, confused, searching, by turns cynical and naïve, wise and impulsive—Opioid, Indiana pierces to the heart of our moment.

"Full of gorgeous language and wild insights."—Nick Flynn Set in the beleaguered heart of Indiana’s opioid crisis, Brian Allen Carr’s timely and tender novel about a teen struggling to find his place in the world—and come up with $800 rent—is at once a moving rumination on the hopeful power of story and a harrowing insight into modern America. It is a book you won’t soon forget. Seventeen-year-old Riggle is living in rural Indiana with his uncle and uncle’s girlfriend after the death of his parents. Now his uncle is missing, probably on a drug binge. It’s Monday, and $800 in rent is due Friday. Riggle, who’s been suspended from school, has to either find his uncle or get the money together himself. His mission exposes him to a motley group of Opioid locals—encounters by turns perplexing, harrowing, and heartening. With empathy and insight, Carr explores what it’s like to be a high school kid in the age of Trump—a time of economic inequality, addiction, Confederate flags, and mass shootings. Through the voice of its unforgettable protagonist—charismatic, confused, searching, by turns cynical and naïve, wise and impulsive—Opioid, Indiana pierces to the heart of our moment.

One doctor's courageous fight to save a small town from a silent epidemic that threatened the community's future--and exposed a national health crisis. When Dr. Will Cooke, an idealistic young physician just out of medical training, set up practice in the small rural community of Austin, Indiana, he had no idea that much of the town was being torn apart by poverty, addiction, and life-threatening illnesses. But he soon found himself at the crossroads of two unprecedented health-care disasters: a national opioid epidemic and the worst drug-fueled HIV outbreak ever seen in rural America. Confronted with Austin's hidden secrets, Dr. Cooke decided he had to do something about them. In taking up the fight for Austin's people, however, he would have to battle some unanticipated foes: prejudice, political resistance, an entrenched bureaucracy--and the dark despair that threatened to overwhelm his own soul. Canary in the Coal Mine is a gripping account of the transformation of a man and his adopted community, a compelling and ultimately hopeful read in the vein of Hillbilly Elegy, Dreamland, and Educated.

Drug overdose, driven largely by overdose related to the use of opioids, is now the leading cause of unintentional injury death in the United States. The ongoing opioid crisis lies at the intersection of two public health challenges: reducing the burden of suffering from pain and containing the rising toll of the harms that can arise from the use of opioid medications. Chronic pain and opioid use disorder both represent complex human conditions affecting millions of Americans and causing untold disability and loss of function. In the context of the growing opioid problem, the U.S. Food and Drug Administration (FDA) launched an Opioids Action Plan in early 2016. As part of this plan, the FDA asked the National Academies of Sciences, Engineering, and Medicine to convene a committee to update the state of the science on pain research, care, and education and to identify actions the FDA and others can take to respond to the opioid epidemic, with a particular focus on informing FDA's development of a formal method for incorporating individual and societal considerations into its risk-benefit framework for opioid approval and monitoring.

"A Divine Comedy of our times."—John Irving, author of The World According to Garp "This book is a miracle.”—Junot Díaz, Pulitzer Prize-winning author of The Brief, Wondrous Life of Oscar Wao A 2022 ReLit Award Finalist • A Winnipeg Free Press Top Read of 2021 Following Original Prin, a NYTBR Editor’s Choice and Globe and Mail Best Book, Dante’s Indiana is an extraordinary journey through the divine comedies and tragedies of our time. Middle-aged, married, but living on his own, Prin has lost his way. Desperate for money and purpose, he moves to small-town Indiana to work for an evangelical millionaire who’s building a theme park inspired by Dante’s Inferno. He quickly becomes involved in the difficult lives of his co-workers and in the wider struggles of their opioid-ravaged community while trying to reconcile with his distant wife and distant God. Both projects spin out of control, and when a Black teenager is killed, creationists, politicians and protesters alike descend. In the midst of this American chaos, Prin risks everything to help the lost and angry souls around him while searching for his own way home. Affecting and strange, intimate and big-hearted, Dante’s Indiana is a darkly divine comedy for our time.

Why medication-assisted treatment, the most effective tool for battling opioid addiction, is significantly underused in the United States. Bronze Winner of the 2021 IPPY Book Award in Health/Medicine/Nutrition, Gold Winner of the 2020 Foreword INDIES Award in Health America's addiction crisis is growing worse. More than 115 Americans die daily from opioid overdoses, with half a million deaths expected in the next decade. Time and again, scientific studies show that medications like Suboxone and methadone are the most reliable and effective treatment, yet more than 60 percent of US addiction treatment centers fail to provide access to them. In The Opioid Fix, Barbara Andraka-Christou highlights both the promise and the underuse of medication-assisted treatment (MAT). Addiction, Andraka-Christou writes, is a chronic medical condition. Why treat it, then, outside of mainstream medicine? Drawing on more than 100 in-depth interviews with people in recovery, their family members, treatment providers, and policy makers, Andraka-Christou reveals a troubling landscape characterized by underregulated treatment centers and unnecessary ideological battles between twelve-step support groups and medication providers. The resistance to MAT—from physicians who won't prescribe it, to drug courts that prohibit it, to politicians who overregulate it—showcases the narrow-mindedness of the system and why it isn't working. Recounting the true stories of people in recovery, this groundbreaking book argues that MAT needs to be available to anyone suffering from opioid addiction. Unlike other books about the opioid crisis, which have largely focused on causal factors like pharmaceutical overprescription and heroin trafficking, this book focuses on people who have already developed an opioid addiction but are struggling to find effective treatment. Validating the experience of hundreds of thousands of Americans, The Opioid Fix sounds a loud call for policy reforms that will help put lifesaving drugs into the hands of those who need them the most.

Offering timely guidance on the junction of the opioid crisis and infectious diseases, this practical handbook by Dr. Brianna L. Norton provides concise yet comprehensive coverage of a growing patient population. Infectious disease specialists are increasingly seeing patients who previously used opiods and now use intravenous drugs. Many challenges are unique to this patient population, including new and growing infections such as hepatitis C, endocarditis, HIV, and hepatitis B. The Opioid Epidemic and Infectious Diseases is an up-to-date, real-world guide that covers the scope of the problem, management guidelines, and much more. - Describes the new landscape of the opioid crisis in the U.S. and its intersection with infectious diseases, including epidemiology, Opioid Use Disorder (OUD) and rural America, and more. - Offers practical guidance on (OUD) and infectious co-morbidities like hepatitis C, STDs, endocarditis, HIV, and hepatitis B. - Covers prevention, treatment, and harm reduction. - Discusses OUD, infectious diseases, and the criminal justice system. - Consolidates today's available information and guidance into a single, convenient resource.

As an adult book, Sam Quinones's Dreamland took the world by storm, winning the NBCC Award for General Nonfiction and hitting at least a dozen Best Book of the Year lists. Now, adapted for the first time for a young adult audience, this compelling reporting explains the roots of the current opiate crisis. In 1929, in the blue-collar city of Portsmouth, Ohio, a company built a swimming pool the size of a football field; named Dreamland, it became the vital center of the community. Now, addiction has devastated Portsmouth, as it has hundreds of small rural towns and suburbs across America. How that happened is the riveting story of Dreamland. Quinones explains how the rise of the prescription drug OxyContin, a miraculous and extremely addictive painkiller pushed by pharmaceutical companies, paralleled the massive influx of black tar heroin--cheap, potent, and originating from one small county on Mexico's west coast, independent of any drug cartel. Introducing a memorable cast of characters--pharmaceutical pioneers, young Mexican entrepreneurs, narcotics investigators, survivors, teens, and parents--Dreamland is a revelatory account of the massive threat facing America and its heartland.

A lyrical, apocalyptic debut novel about addiction, friendship, and the struggle for survival at the height of an epidemic. The sickness started with a single child and quickly spread: you could get high by drinking your own shadow. Artificial lights were destroyed so addicts could sip shadow at night in the pure moonlight. Gangs of shadow addicts chased down children on playgrounds, rounded up old ladies from retirement homes. Cities were destroyed and governments fell. And if your shadow was sipped entirely, you became one of them, had to drink the shadows of others or go mad. One hundred and fifty years later, what’s left of the world is divided between the highly regimented life of those inside dome cities who are protected from natural light (and natural shadows), and those forced to the dangerous, hardscrabble life in the wilds outside. In rural Texas, Mira, her shadow-addicted-friend Murk, and an ex-domer named Bale search for a possible mythological cure to the shadow sickness—but they must find it, it is said, before the return of Halley’s Comet, which is only days away.

NPR Best Book of 2019 A bioethicist’s eloquent and riveting memoir of opioid dependence and withdrawal—a harrowing personal reckoning and clarion call for change not only for government but medicine itself, revealing the lack of crucial resources and structures to handle this insidious nationwide epidemic. Travis Rieder’s terrifying journey down the rabbit hole of opioid dependence began with a motorcycle accident in 2015. Enduring half a dozen surgeries, the drugs he received were both miraculous and essential to his recovery. But his most profound suffering came several months later when he went into acute opioid withdrawal while following his physician’s orders. Over the course of four excruciating weeks, Rieder learned what it means to be “dope sick”—the physical and mental agony caused by opioid dependence. Clueless how to manage his opioid taper, Travis’s doctors suggested he go back on the drugs and try again later. Yet returning to pills out of fear of withdrawal is one route to full-blown addiction. Instead, Rieder continued the painful process of weaning himself. Rieder’s experience exposes a dark secret of American pain management: a healthcare system so conflicted about opioids, and so inept at managing them, that the crisis currently facing us is both unsurprising and inevitable. As he recounts his story, Rieder provides a fascinating look at the history of these drugs first invented in the 1800s, changing attitudes about pain management over the following decades, and the implementation of the pain scale at the beginning of the twenty-first century. He explores both the science of addiction and the systemic and cultural barriers we must overcome if we are to address the problem effectively in the contemporary American healthcare system. In Pain is not only a gripping personal account of dependence, but a groundbreaking exploration of the intractable causes of America’s opioid problem and their implications for resolving the crisis. Rieder makes clear that the opioid crisis exists against a backdrop of real, debilitating pain—and that anyone can fall victim to this epidemic.