Indoor residual spraying (IRS) involves applying residual insecticide to potential vector resting sites on the interior surfaces of human dwellings or other buildings. The main aim of IRS is to kill vectors before they are able to transmit pathogens to humans. When carried out correctly, IRS has historically been shown to be a powerful intervention to reduce adult vector density and longevity for mosquitoes, sand flies and triatomine bugs and can reduce the transmission of vector-borne diseases. This operational manual is designed to provide guidance on the establishment, management, implementation, reporting and evaluation of safe and effective IRS campaigns within the context of a locally adapted and sustainable vector control programme, in line with the Global vector control response 2017–2030. It provides information according to current WHO recommendations and standards on IRS and recognizes that IRS can potentially target multiple diseases in areas where endophilic vectors coexist. The key audience for this document is vector-borne disease control programme managers and staff, as well as implementing or private-sector partners at the national, provincial/state or local levels, who are responsible for the design, planning or implementation of vector control operations.

The course module provides the students with the knowledge and skills for developing and implementing effective strategies to control disease vectors and domestic pests (e.g. integrated vector management), with emphasis on improved management of public health pesticides throughout their life cycle. Alternative methods and strategies for pest and vector control, their cost-effectiveness and their sustainability are discussed. Students will also examine the WHO strategies, policies and guidelines for using pesticides in public health. This course was first developed in 2012 by the World Health Organization (WHO) in collaboration with the University of Cape Town (South Africa) and was revised in 2015. The current version incorporates major revisions and updates of the course material.

This toolkit for integrated vector management (IVM) is designed to help national and regional programme managers coordinate across sectors to design and run large IVM programmes. It is an extension of earlier guidance and teaching material published by the World Health Organization (WHO): Handbook for integrated vector management Monitoring and evaluation indicators for integrated vector management Guidance on policy-making for integrated vector management and Core structure for training curricula on integrated vector management. The toolkit provides the technical detail required to plan implement monitor and evaluate an IVM approach. IVM can be used when the aim is to control or eliminate vector-borne diseases and can also contribute to insecticide resistance management. This toolkit provides information on where vector-borne diseases are endemic and what interventions should be used presenting case studies on IVM as well as relevant guidance documents for reference. The diseases that are the focus of this toolkit are malaria lymphatic filariasis dengue leishmaniasis onchocerciasis human African trypanosomiasis and schistosomiasis. It also includes information on other viral diseases (Rift Valley fever West Nile fever Chikungunya yellow fever) and trachoma. If other vector-borne diseases appear in a country or area vector control with an IVM approach should be adopted as per national priorities. Malaria as one of the most important vector-borne diseases in sub-Saharan Africa is the main focus of this document. Programmes targeting other vector-borne diseases can learn from the experiences gained from malaria vector control and presented here.

This document is the second in a series of global reports describing progress towards the 2030 targets set in Ending the neglect to attain the Sustainable Development Goals: a road map for neglected tropical diseases 2021–2030. It describes a wide range of activities, accomplishments and challenges across the portfolio of NTDs and across all six WHO regions. The report presents epidemiological and programmatic data for 2022, which were gathered, compiled and analysed in 2023. In some cases, 2023 data are available and presented; in other cases, less recent information is included, when 2022 data are not available. In addition, it presents the main facts or events that occurred in 2023. In line with the road map’s companion document Ending the neglect to attain the Sustainable Development Goals: a framework for monitoring and evaluating progress of the road map for neglected tropical diseases 2021−2030, the report includes quantitative information on the status of the overarching, cross-cutting and disease-specific indicators. This is followed by qualitative information on each of the three road map pillars and on regional and country progress. The conclusions of the report and way forward are further complemented by annexes on cross-cutting indicator 6, status of donated medicines for treatment of NTDs, articles on NTDs published in the Weekly Epidemiological Record, target product profiles published as of 31 December 2023 and the list of global NTD reports published by WHO so far.

Integrated vector management (IVM) is a rational decision-making process for optimal use of resources for vector control. The aim of the IVM approach is to contribute to achievement of the global targets set for vector-borne disease control, by making vector control more efficient, cost-effective, ecologically sound and sustainable. Use of IVM helps vector control programs to find and use more local evidence, to integrate interventions where appropriate and to collaborate within the health sector and with other sectors, as well as with households and communities. By reorientating to IVM, vector control programs will be better able to meet the growing challenges in the control of malaria, dengue and other vector-borne diseases in the face of dwindling public sector human and financial resources. This handbook presents an operational framework to guide managers and those implementing vector-borne disease control programs in designing more efficient, cost-effective systems. As a national IVM policy and an intersectoral steering committee are essential for establishing IVM as a national strategy, the handbook begins with the policy and institutional framework for IVM. Policy analysis is a means for identifying options for policy reform and suggesting instruments for implementing policy. IVM transforms the conventional system of vector control by making it more evidence-based, integrated and participative. This may require changes in roles, responsibilities and organizational links. The transition to IVM involves both reorientation of vector-borne disease control programs and embedding IVM within local health systems. Intersectoral partnerships and collaboration at both national and local levels will result in cost savings and benefits to other health services. Other relevant sectors, such as agriculture, environment, mining, industry, public works, local government and housing, should incorporate IVM and vector control into their own activities to prevent vector proliferation and disease transmission. Planning and implementing IVM involve assessing the epidemiological and vector situation at country level, analyzing the local determinants of disease, identifying and selecting vector control methods, assessing requirements and resources and designing locally appropriate implementation strategies. Solid evidence on the cost-effectiveness of interventions and their underlying parameters and a comprehensive vector surveillance system are essential for locally appropriate decision-making. Capacity-building, in particular human resource development, is a major challenge, because the IVM strategy requires skilled staff and adequate infrastructure at central and local levels. The handbook outlines the core functions and essential competence required for IVM at central and local levels, complementing a separate set of documents containing the Core structure for training curricula on integrated vector management and associated training materials. Like any new approach, IVM must be actively advocated and communicated in order to become established. The handbook lays out the elements and processes of IVM to enable policy-makers, donors and implementing partners to use it for vector-borne disease control. During the period of transition and consolidation of an IVM strategy, regular feedback is required on performance and impact in order to ensure continued support. The general public must also be made aware of the strategy and participate in its implementation. The communication tools for reaching the public are the media and various types of educational interventions to increase their knowledge and skills, which should lead to behavioral change and empowerment. The final section presents a comprehensive framework for monitoring and evaluation of IVM, covering aspects discussed in the previous sections. Indicators and methods for measuring process, outcomes and impact are proposed.

This manual makes recommendations on a standardized approach for case management of cutaneous leishmaniasis across the WHO Eastern Mediterranean Region. It was conceived as a practical guide for health workers dealing with the complexities of diagnosing and treating cutaneous leishmaniasis. The manual provides a step-wise decision algorithm for the treatment of cutaneous leishmaniasis taking into consideration the Leishmania strains present in the Region. Annexes include detailed standard operating procedures for diagnosis and various treatment options. The manual also emphasizes the importance of monitoring and evaluation to continuously assess the effectiveness of the approach used for case management. It provides a set of indicators for evaluation and additional annexes provide templates for surveillance data collection and reporting.

"A malaria surveillance system consists of the tools, procedures, people and structures that generate information on malaria cases and deaths, which can be used for planning, monitoring and evaluating malaria control programmes. An effective malaria surveillance system enables programme managers to: identify the areas or population groups most affected by malaria; identify trends in cases and deaths that require additional intervention, e.g. epidemics; and assess the impact of control measures. With this information, programmes can direct resources to the populations most in need and respond to unusual trends, such as outbreaks of cases or the absence of a decrease in the number of cases despite widespread implementation of interventions. As a result, progress in malaria control can be accelerated and wastage of resources avoided."--Page 1.

This book presents a thorough and systematic approach of microbiology in a very clear,concise, simplified and easily understandable manner. The text is amply illustrated by largenumber of figures, flowcharts, tables and boxes. This will help not only in understanding theconcepts to clear the professional exams but will also teach the importance and application ofmicrobiology in clinical practice.• Focus on clinical and laboratory aspects of infectious diseases covering bacterial, tubercular,viral, parasitic and fungal infections.• Organization of the text into sections helps to recollect the facts easily.• Chapter outline in the beginning of each chapter helps to facilitate self-learning by thestudents.• Syndromic approach to common syndromes highlights the important causes and laboratorydiagnostic approach.• Flowcharts and line diagrams represent the diagnostic procedures and life cycles.• Questions given at the end of chapters for self-assessment of topics.• Multiple choice questions section-by-section at the end of the book for self-assessment ofthe topics studied.Online Resources at www.medenact.com• Complimentary access to full e-book.• Procedural animations.