This offers a wealth of detail, and is a crucial reference for everyone who suffers from this painful condition. Senneff illustrates the various treatments without judging them. This arms patients with the information they need so they and their doctor—and not the doctor alone—can decide on what treatments to try. This is especially important for peripheral neuropathy because what works for a specific patient remains very much a trial-and-error proposition.

Examines the nature of neuropathic pain in depth. Updates studies on the efficacy of various drugs (including several new pharmaceuticals), as well as other medical and alternative procedures used to treat neuropathic pain. Highlights specific nutrient supplementation strategies and reports on the most beneficial forms of certain supplements, based on new information. Reports on navel treatment approaches such as nerve regeneration, cellular therapies (including gene therapy, stem cell technology, and nerve cell disablement, and promising, newly developed drugs awaiting government approval. Describes unusual neuropathies, best ways of working with doctors, and new sources of patient assistance.

Peripheral neuropathy affects 10 to 20 million people in the U.S, including ten per cent of all people who have diabetes. This condition has numerous causes, but can be associated with diseases such as HIV, alcoholism, and lupus, and may result from treatments for other medical conditions, such as cancer chemotherapy. Symptoms include pain, numbness, loss of balance, and tingling in the extremities. Although a widespread condition, most people don't know about it, and when diagnosed find it difficult to obtain information. Peripheral Neuropathy, by Norman Latov, Professor of Neurology at the Weill Medical College of Cornell University, explains what we know about neuropathy, including its causes and manifestations, and what can be done to manage it. Topics covered include: The causes of peripheral neuropathy Drug therapy for the condition itself and for managing symptoms such as pain Interventional therapy Caring for your feet Personal accounts of people living with neuropathy Alternative medicines, and much more This indispensable guide will help millions of people understand this condition so that they can take control of their lives and make informed decisions. In addition, it will be a useful resource for their families, caregivers, and health care providers.

Healing and symptom relief from an expert in treating this debilitating and dangerous condition. Nearly one in fifteen people—that's 20 million people in the United States—suffers from peripheral neuropathy, or nerve damage. Caused by such conditions as diabetes, cancer, vitamin deficiencies, and kidney disease as well as certain drugs and toxins, neuropathy brings numbness, tingling, and burning in the feet, legs, and fingertips. Neuropathy can be more than uncomfortable—it can be disabling: people whose fingertips are numb may find it hard to button clothing and complete other everyday tasks. Neuropathy is often dangerous, as well: people who cannot feel their feet are more likely to stumble and fall, and they may not notice injuries that need medical attention. Dr. Janice F. Wiesman, a neurologist with twenty years of experience helping people who have neuropathy find relief, shares her special insights into this painful and debilitating condition. With exceptional clarity, Dr. Wiesman begins by outlining the basics of nerve anatomy and function. She explains how peripheral neuropathy is diagnosed and treated, describes neuropathy’s disparate causes, and offers readers lifestyle changes that can help keep nerves healthy. A useful glossary defines terms, patient stories offer real-world experiences, and illustrations provide a visual key to the condition. A detailed resources section points the reader to reliable web sites and organizations that offer more help. Concentrating on the most common types of neuropathy, Dr. Wiesman provides hope, help, and comfort to patients, families, and caregivers.

Disorders of the peripheral nervous system (PNS) are the cause of prominent neurological symptoms including weakness, sensory loss, pain and autonomic dysfunction associated with deficits, morbidity and mortality. These disorders may be primary hereditary or cryptogenic neurologic disorders confined to the PNS or part of the pathology of both the central nervous system and the PNS. Most PNS disorders are secondary to other system disorders and may be responsive to treatment of the primary disease. Important advances have been obtained in several areas including molecular genetics, biochemistry, immunology, morphology and physiology that have enhanced our understanding of the causes and consequences of damage to peripheral nerve. Understanding of both these groups of PNS diseases has greatly expanded over recent years and has led to important advances of treatment both to protect and to repair damages of peripheral nerve. This volume provides an overview of the state-of-the-art of examination, diagnosis and treatment of these very diverse disorders and will be of interest to both the research and clinical neuroscience and neurology communities. Covers both hereditary and cryptogenic neurologic disorders Includes advances in the basic science of PNS from molecular genetics, biochemistry, immunology, morphology and physiology Detailed coverage of neuropathy in connective tissue disorders, infectious disorders, metabolic disorders and malignancy

The brain is the most complex organ in our body. Indeed, it is perhaps the most complex structure we have ever encountered in nature. Both structurally and functionally, there are many peculiarities that differentiate the brain from all other organs. The brain is our connection to the world around us and by governing nervous system and higher function, any disturbance induces severe neurological and psychiatric disorders that can have a devastating effect on quality of life. Our understanding of the physiology and biochemistry of the brain has improved dramatically in the last two decades. In particular, the critical role of cations, including magnesium, has become evident, even if incompletely understood at a mechanistic level. The exact role and regulation of magnesium, in particular, remains elusive, largely because intracellular levels are so difficult to routinely quantify. Nonetheless, the importance of magnesium to normal central nervous system activity is self-evident given the complicated homeostatic mechanisms that maintain the concentration of this cation within strict limits essential for normal physiology and metabolism. There is also considerable accumulating evidence to suggest alterations to some brain functions in both normal and pathological conditions may be linked to alterations in local magnesium concentration. This book, containing chapters written by some of the foremost experts in the field of magnesium research, brings together the latest in experimental and clinical magnesium research as it relates to the central nervous system. It offers a complete and updated view of magnesiums involvement in central nervous system function and in so doing, brings together two main pillars of contemporary neuroscience research, namely providing an explanation for the molecular mechanisms involved in brain function, and emphasizing the connections between the molecular changes and behavior. It is the untiring efforts of those magnesium researchers who have dedicated their lives to unraveling the mysteries of magnesiums role in biological systems that has inspired the collation of this volume of work.

This book provides a clear and integrated guide to the diagnostic pathways and therapeutic options available for the treatment of diabetic foot syndrome. The link between the location of the lesion and its potential causes are discussed in relation to its diagnosis, biomechanics, treatment and prognosis. Chapters covering interdigital lesions, the lateral side of the foot, torsion of the hallux, and the charcot foot are included. Diabetic Foot Syndrome: From Entity to Therapy aims to facilitate interdisciplinary understanding and is relevant to endocrinologists, as well as vascular and orthopedic surgeons.

The Oxford Textbook of Vascular Surgery draws on the expertise of over 130 specialist contributors to encompass the field of vascular surgery. Through the use of figures, findings of contemporary trials, and additional online content, this textbook is an excellent study material for surgical trainees entering their final two years of training, in addition to serving as an effective reference source for practicing surgeons. This volume discusses the epidemiology, vascular biology, clinical features and management of diseases that affect the vasculature and contains dedicated chapters which address topics such as paediatric surgery, damage control surgery, and amputations. The text follows a logical framework which complements the published Intercollegiate Surgery Curriculum making it particularly useful in preparation for the Intercollegiate Examination. The online version of The Oxford Textbook of Vascular Surgery is free for twelve months to individual purchasers of this book and contains the full text of the print edition, links to external sources and informative videos demonstrating current surgical techniques, making this a valuable resource for practicing surgeons. The field of vascular surgery has advanced rapidly in recent years and has expanded to include the techniques of interventional radiology and cardiology which are also extensively covered in this volume, making it an authoritative modern text. By combining contemporary evidence-based knowledge with informative figures, online resources and links to the current training curriculum, The Oxford Textbook of Vascular Surgery is a highly valuable source of information and will become the standard reference text for all who study vascular disease and its treatment.

This pioneering textbook is the first one ever on diabetic foot problems. With contributions from a multidisciplinary panel of experts, it presents a comprehensive curriculum on the topic. This includes global and socio-economic aspects of diabetes; a team approach; basic science of the foot (anatomy and biomechanics); clinical assessment and classification systems for diabetic foot problems; endocrine aspects; diabetic foot infections (clinical presentation and management); amputations in diabetic foot surgery (predictive factors, major and distal amputations, rehabilitation and phantom pain management); care of diabetic wounds (including the role of the latest technologically advanced dressings, vacuum dressings, anodyne therapy, ultrasonic debridement and extracorporeal shockwave therapy); and diabetic footcare and diabetic footwear.

Foot pain and injuries can thwart even the most experienced athletes. Foot expert and ultra runner John Vonhof discredits the conventional wisdom of 'no pain, no gain, ' teaching instead how the interplay of anatomy, biomechanics, and footwear can lead to happy or hurting feet. With a focus on individual and team care, the 6th edition of Fixing Your Feet covers all that any active person needs to know to find out what works now and also hundreds of miles down the road. This sixth edition has an important new chapter, Blister Prevention - A New Paradigm. It contains new information about blister formation and introduces the concept of shear, which in turn, changes the way we look at blister prevention and treatment. This comprehensive resources covers the full gamut of footwear basics, prevention, and treatments. If it can happen to a foot, it's covered in this book.