The Cold War reconsidered as a limited nuclear war "[A] grimly important analysis of the cold war."--Andrew Robinson, Nature "Inexorable clarity and care for his fellow humans mark Robert Jacobs's guide to the Cold War as a limited nuclear war, whose harms disfigure any possible future."--Norma Field, author of In the Realm of a Dying Emperor: Japan at Century's End In the fall of 1961, President Kennedy somberly warned Americans about deadly radioactive fallout clouds extending hundreds of miles from H-bomb detonations, yet he approved ninety-six U.S. nuclear weapon tests for 1962. Cold War nuclear testing, production, and disasters like Chernobyl and Fukushima have exposed millions to dangerous radioactive particles; these millions are the global hibakusha. Many communities continue to be plagued with dire legacies and ongoing risks: sickness and early mortality, forced displacement, uncertainty and anxiety, dislocation from ancestors and traditional lifestyles, and contamination of food sources and ecosystems. Robert A. Jacobs re-envisions the history of the Cold War as a slow nuclear war, fought on remote battlegrounds against populations powerless to prevent the contamination of their lands and bodies. His comprehensive account necessitates a profound rethinking of the meaning, costs, and legacies of our embrace of nuclear weapons and technologies.

“An intimate and deeply human memoir that shows why we should all be concerned about nuclear safety, and the dangers of ignoring science in the name of national security.”—Rebecca Skloot, #1 New York Times bestselling author of The Immortal Life of Henrietta Lacks A shocking account of the government’s attempt to conceal the effects of the toxic waste released by a secret nuclear weapons plant in Colorado and a community’s vain search for justice—soon to be a feature documentary Kristen Iversen grew up in a small Colorado town close to Rocky Flats, a secret nuclear weapons plant once designated "the most contaminated site in America." Full Body Burden is the story of a childhood and adolescence in the shadow of the Cold War, in a landscape at once startlingly beautiful and--unknown to those who lived there--tainted with invisible yet deadly particles of plutonium. It's also a book about the destructive power of secrets--both family and government. Her father's hidden liquor bottles, the strange cancers in children in the neighborhood, the truth about what was made at Rocky Flats--best not to inquire too deeply into any of it. But as Iversen grew older, she began to ask questions and discovered some disturbing realities. Based on extensive interviews, FBI and EPA documents, and class-action testimony, this taut, beautifully written book is both captivating and unnerving.

The Cold War reconsidered as a limited nuclear war “Inexorable clarity and care for his fellow humans mark Robert Jacobs's guide to the Cold War as a limited nuclear war, whose harms disfigure any possible future.”—Norma Field, author of In the Realm of a Dying Emperor: Japan at Century’s End In the fall of 1961, President Kennedy somberly warned Americans about deadly radioactive fallout clouds extending hundreds of miles from H‑bomb detonations, yet he approved ninety‑six US nuclear weapon tests for 1962. Cold War nuclear testing, production, and disasters like Chernobyl and Fukushima have exposed millions to dangerous radioactive particles; these millions are the global hibakusha. Many communities continue to be plagued with dire legacies and ongoing risks: sickness and early mortality, forced displacement, uncertainty and anxiety, dislocation from ancestors and traditional lifestyles, and contamination of food sources and ecosystems. Robert A. Jacobs re‑envisions the history of the Cold War as a slow nuclear war, fought on remote battlegrounds against populations powerless to prevent the contamination of their lands and bodies. His comprehensive account necessitates a profound rethinking of the meaning, costs, and legacies of our embrace of nuclear weapons and technologies.

Nuclear Architecture and Dynamics provides a definitive resource for (bio)physicists and molecular and cellular biologists whose research involves an understanding of the organization of the genome and the mechanisms of its proper reading, maintenance, and replication by the cell. This book brings together the biochemical and physical characteristics of genome organization, providing a relevant framework in which to interpret the control of gene expression and cell differentiation. It includes work from a group of international experts, including biologists, physicists, mathematicians, and bioinformaticians who have come together for a comprehensive presentation of the current developments in the nuclear dynamics and architecture field. The book provides the uninitiated with an entry point to a highly dynamic, but complex issue, and the expert with an opportunity to have a fresh look at the viewpoints advocated by researchers from different disciplines. - Highlights the link between the (bio)chemistry and the (bio)physics of chromatin - Deciphers the complex interplay between numerous biochemical factors at task in the nucleus and the physical state of chromatin - Provides a collective view of the field by a large, diverse group of authors with both physics and biology backgrounds

Within the past two decades, extraordinary new functions for the nucleolus have begun to appear, giving the field a new vitality and generating renewed excitement and interest. These new discoveries include both newly-discovered functions and aspects of its conventional role. The Nucleolus is divided into three parts: nucleolar structure and organization, the role of the nucleolus in ribosome biogenesis, and novel functions of the nucleolus.

Written and edited by experts in the field, this volume includes contributions discussing the relationship between nuclear structure and function, the various nuclear bodies that have been identified, and the organization of the nuclear lamina and nuclear pore complex.

Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates

This volume explores nuclear structure and trafficking involving or relevant to RNA and RNPs. Topics include advances and current problems in the structural organization of different subnuclear compartments, Cajal bodies and gems, speckles containing splicing factors, and PML bodies characteristic of ProMyelocytic leukemia. The book also describes the dynamic aspects of RNA trafficking and the latest technologies for live cell imaging of mRNA.