This book collects new results, concepts and further developments of NMF. The open problems discussed include, e.g. in bioinformatics: NMF and its extensions applied to gene expression, sequence analysis, the functional characterization of genes, clustering and text mining etc. The research results previously scattered in different scientific journals and conference proceedings are methodically collected and presented in a unified form. While readers can read the book chapters sequentially, each chapter is also self-contained. This book can be a good reference work for researchers and engineers interested in NMF, and can also be used as a handbook for students and professionals seeking to gain a better understanding of the latest applications of NMF.

This book collects new results, concepts and further developments of NMF. The open problems discussed include, e.g. in bioinformatics: NMF and its extensions applied to gene expression, sequence analysis, the functional characterization of genes, clustering and text mining etc. The research results previously scattered in different scientific journals and conference proceedings are methodically collected and presented in a unified form. While readers can read the book chapters sequentially, each chapter is also self-contained. This book can be a good reference work for researchers and engineers interested in NMF, and can also be used as a handbook for students and professionals seeking to gain a better understanding of the latest applications of NMF.

The overwhelming data produced everyday and the increasing performance and cost requirements of applications are transversal to a wide range of activities in society, from science to industry. In particular, the magnitude and complexity of the tasks that Machine Learning (ML) algorithms have to solve are driving the need to devise adaptive many-core machines that scale well with the volume of data, or in other words, can handle Big Data. This book gives a concise view on how to extend the applicability of well-known ML algorithms in Graphics Processing Unit (GPU) with data scalability in mind. It presents a series of new techniques to enhance, scale and distribute data in a Big Learning framework. It is not intended to be a comprehensive survey of the state of the art of the whole field of machine learning for Big Data. Its purpose is less ambitious and more practical: to explain and illustrate existing and novel GPU-based ML algorithms, not viewed as a universal solution for the Big Data challenges but rather as part of the answer, which may require the use of different strategies coupled together.

Nonnegative matrix factorization (NMF) in its modern form has become a standard tool in the analysis of high-dimensional data sets. This book provides a comprehensive and up-to-date account of the most important aspects of the NMF problem and is the first to detail its theoretical aspects, including geometric interpretation, nonnegative rank, complexity, and uniqueness. It explains why understanding these theoretical insights is key to using this computational tool effectively and meaningfully. Nonnegative Matrix Factorization is accessible to a wide audience and is ideal for anyone interested in the workings of NMF. It discusses some new results on the nonnegative rank and the identifiability of NMF and makes available MATLAB codes for readers to run the numerical examples presented in the book. Graduate students starting to work on NMF and researchers interested in better understanding the NMF problem and how they can use it will find this book useful. It can be used in advanced undergraduate and graduate-level courses on numerical linear algebra and on advanced topics in numerical linear algebra and requires only a basic knowledge of linear algebra and optimization.

Computational Genomics with R provides a starting point for beginners in genomic data analysis and also guides more advanced practitioners to sophisticated data analysis techniques in genomics. The book covers topics from R programming, to machine learning and statistics, to the latest genomic data analysis techniques. The text provides accessible information and explanations, always with the genomics context in the background. This also contains practical and well-documented examples in R so readers can analyze their data by simply reusing the code presented. As the field of computational genomics is interdisciplinary, it requires different starting points for people with different backgrounds. For example, a biologist might skip sections on basic genome biology and start with R programming, whereas a computer scientist might want to start with genome biology. After reading: You will have the basics of R and be able to dive right into specialized uses of R for computational genomics such as using Bioconductor packages. You will be familiar with statistics, supervised and unsupervised learning techniques that are important in data modeling, and exploratory analysis of high-dimensional data. You will understand genomic intervals and operations on them that are used for tasks such as aligned read counting and genomic feature annotation. You will know the basics of processing and quality checking high-throughput sequencing data. You will be able to do sequence analysis, such as calculating GC content for parts of a genome or finding transcription factor binding sites. You will know about visualization techniques used in genomics, such as heatmaps, meta-gene plots, and genomic track visualization. You will be familiar with analysis of different high-throughput sequencing data sets, such as RNA-seq, ChIP-seq, and BS-seq. You will know basic techniques for integrating and interpreting multi-omics datasets. Altuna Akalin is a group leader and head of the Bioinformatics and Omics Data Science Platform at the Berlin Institute of Medical Systems Biology, Max Delbrück Center, Berlin. He has been developing computational methods for analyzing and integrating large-scale genomics data sets since 2002. He has published an extensive body of work in this area. The framework for this book grew out of the yearly computational genomics courses he has been organizing and teaching since 2015.

This book presents the algorithms used to provide recommendations by exploiting matrix factorization and tensor decomposition techniques. It highlights well-known decomposition methods for recommender systems, such as Singular Value Decomposition (SVD), UV-decomposition, Non-negative Matrix Factorization (NMF), etc. and describes in detail the pros and cons of each method for matrices and tensors. This book provides a detailed theoretical mathematical background of matrix/tensor factorization techniques and a step-by-step analysis of each method on the basis of an integrated toy example that runs throughout all its chapters and helps the reader to understand the key differences among methods. It also contains two chapters, where different matrix and tensor methods are compared experimentally on real data sets, such as Epinions, GeoSocialRec, Last.fm, BibSonomy, etc. and provides further insights into the advantages and disadvantages of each method. The book offers a rich blend of theory and practice, making it suitable for students, researchers and practitioners interested in both recommenders and factorization methods. Lecturers can also use it for classes on data mining, recommender systems and dimensionality reduction methods.

This second and revised edition contains a detailed introduction to the key classes of intelligent data analysis methods. The twelve coherently written chapters by leading experts provide complete coverage of the core issues. The first half of the book is devoted to the discussion of classical statistical issues. The following chapters concentrate on machine learning and artificial intelligence, rule induction methods, neural networks, fuzzy logic, and stochastic search methods. The book concludes with a chapter on visualization and an advanced overview of IDA processes.

This book constitutes the refereed proceedings of the 8th International Conference on Independent Component Analysis and Signal Separation, ICA 2009, held in Paraty, Brazil, in March 2009. The 97 revised papers presented were carefully reviewed and selected from 137 submissions. The papers are organized in topical sections on theory, algorithms and architectures, biomedical applications, image processing, speech and audio processing, other applications, as well as a special session on evaluation.

This book provides a broad survey of models and efficient algorithms for Nonnegative Matrix Factorization (NMF). This includes NMF’s various extensions and modifications, especially Nonnegative Tensor Factorizations (NTF) and Nonnegative Tucker Decompositions (NTD). NMF/NTF and their extensions are increasingly used as tools in signal and image processing, and data analysis, having garnered interest due to their capability to provide new insights and relevant information about the complex latent relationships in experimental data sets. It is suggested that NMF can provide meaningful components with physical interpretations; for example, in bioinformatics, NMF and its extensions have been successfully applied to gene expression, sequence analysis, the functional characterization of genes, clustering and text mining. As such, the authors focus on the algorithms that are most useful in practice, looking at the fastest, most robust, and suitable for large-scale models. Key features: Acts as a single source reference guide to NMF, collating information that is widely dispersed in current literature, including the authors’ own recently developed techniques in the subject area. Uses generalized cost functions such as Bregman, Alpha and Beta divergences, to present practical implementations of several types of robust algorithms, in particular Multiplicative, Alternating Least Squares, Projected Gradient and Quasi Newton algorithms. Provides a comparative analysis of the different methods in order to identify approximation error and complexity. Includes pseudo codes and optimized MATLAB source codes for almost all algorithms presented in the book. The increasing interest in nonnegative matrix and tensor factorizations, as well as decompositions and sparse representation of data, will ensure that this book is essential reading for engineers, scientists, researchers, industry practitioners and graduate students across signal and image processing; neuroscience; data mining and data analysis; computer science; bioinformatics; speech processing; biomedical engineering; and multimedia.

This textbook provides a solid mathematical basis for understanding popular data science algorithms for clustering and classification and shows that an in-depth understanding of the mathematics powering these algorithms gives insight into the underlying data. It presents a step-by-step derivation of these algorithms, outlining their implementation from scratch in a computationally sound way. Mathematics of Data Science: A Computational Approach to Clustering and Classification proposes different ways of visualizing high-dimensional data to unveil hidden internal structures, and nearly every chapter includes graphical explanations and computed examples using publicly available data sets to highlight similarities and differences among the algorithms. This self-contained book is geared toward advanced undergraduate and beginning graduate students in the mathematical sciences, engineering, and computer science and can be used as the main text in a semester course. Researchers in any application area where data science methods are used will also find the book of interest. No advanced mathematical or statistical background is assumed.