Physiology or medicine was the third prize area Alfred Nobel mentioned in his will. Nobel had an active interest in medical research. He came into contact with Swedish physiologist Jöns Johansson through Karolinska Institute around 1890. Johansson worked for a brief period in Nobel's laboratory in Sevran, France during the same year. The Nobel Prize in Physiology or Medicine is awarded by the Nobel Assembly at Karolinska Institute. This volume is a collection of the Nobel lectures delivered by the Nobel Laureates, together with their biographies and the presentation speeches for the period 2006-2010.List of Laureates and their award citations:(2006) Andrew Z Fire and Craig C Mello — for their discovery of RNA interference-gene silencing by double-stranded RNA;(2007) Mario R Capecchi, Martin J Evans and Oliver Smithies — for their discoveries of principles for introducing specific gene modifications in mice by the use of embryonic stem cells;(2008) Harald zur Hausen — for his discovery of human papilloma viruses causing cervical cancer, and Françoise Barré-Sinoussi and Luc Montagnier — for their discovery of human immunodeficiency virus;(2009) Elizabeth H Blackburn, Carol W Greider and Jack W Szostak — for the discovery of how chromosomes are protected by telomeres and the enzyme telomerase;(2010) Robert G Edwards — for the development of in vitro fertilization.

This volume is a collection of the Nobel Lectures delivered by the prizewinners, together with their biographies and the presentation speeches at the award ceremonies in Stockholm for the period 2001 - 2005. Each Nobel Lecture is based on the work for which the laureate was awarded the prize. This volume of inspiring lectures should be on the bookshelf of every keen student, teacher and professor of physiology/medicine as well as of those in related fields.The following is a list of the Nobel laureates during 2001 - 2005 with a description of the works that won them their prizes: (2001) Leland H Hartwell, Tim Hunt & Sir Paul Nurse -- for their discoveries of key regulators of the cell cycle; (2002) Sydney Brenner, H Robert Horvitz & John E Sulston -- for their discoveries concerning genetic regulation of organ development and programmed cell death; (2003) Paul C Lauterbur & Sir Peter Mansfield -- for their discoveries concerning magnetic resonance imaging; (2004) Richard Axel & Linda B Buck -- for their discoveries of odorant receptors and the organization of the olfactory system; (2005) Barry J Marshall & J Robin Warren -- for their discovery of the bacterium Helicobacter pylori and its role in gastritis and peptic ulcer disease.

During the period 1991 – 1995, important areas of physiological/medical research being recognized were ion channels in cells, protein phosphorylation, split genes, G-proteins and genetic control of embryonic development. The following is a list of the Nobel laureates for those years, with a description of the works that won them their prizes: (1991) E NEHER & B SAKMANN — for their discoveries concerning the function of single ion channels in cells; (1992) E H FISCHER & E G KREBS — for their discoveries concerning reversible protein phosphorylation as a biological regulatory mechanism; (1993) R J ROBERTS & P A SHARP — for their discoveries of split genes; (1994) A G GILMAN & M RODBELL — for their discovery of G-proteins and the role of these proteins in signal transduction in cells; (1995) E B LEWIS, C NÜSSLEIN-VOLHARD & E F WIESCHAUS — for their discoveries concerning the genetic control of early embryonic development.

This book brings together in one volume fifteen Nobel Prize-winning discoveries that have had the greatest impact upon medical science and the practice of medicine during the 20th century and up to the present time. Its overall aim is to enlighten, entertain and stimulate. This is especially so for those who are involved in or contemplating a career in medical research. Anyone interested in the particulars of a specific award or Laureate can obtain detailed information on the topic by accessing the Nobel Foundation''s website. In contrast, this book aims to provide a less formal and more personal view of the science and scientists involved, by having prominent academics write a chapter each about a Nobel Prize-winning discovery in their own areas of interest and expertise.

Physiology or medicine was the third prize area Alfred Nobel mentioned in his will. Nobel had an active interest in medical research. He came into contact with Swedish physiologist Jöns Johansson through Karolinska Institute around 1890. Johansson worked for a brief period in Nobel's laboratory in Sevran, France during the same year. The Nobel Prize in Physiology or Medicine is awarded by the Nobel Assembly at Karolinska Institute. This volume is a collection of the Nobel lectures delivered by the Nobel Laureates, together with their biographies and the presentation speeches for the period 2006-2010. List of Laureates and their award citations: (2006) Andrew Z Fire and Craig C Mello -- for their discovery of RNA interference-gene silencing by double-stranded RNA; (2007) Mario R Capecchi, Martin J Evans and Oliver Smithies -- for their discoveries of principles for introducing specific gene modifications in mice by the use of embryonic stem cells; (2008) Harald zur Hausen --for his discovery of human papilloma viruses causing cervical cancer, and Françoise Barré-Sinoussi and Luc Montagnier -- for their discovery of human immunodeficiency virus; (2009) Elizabeth H Blackburn, Carol W Greider and Jack W Szostak -- for the discovery of how chromosomes are protected by telomeres and the enzyme telomerase; (2010) Robert G Edwards -- for the development of in vitro fertilization.--

The field of solid state ionics deals with ionically conducting materials in the solid state and numerous devices based on such materials. Solid state ionic materials cover a wide spectrum, ranging from inorganic crystalline and polycrystalline solids, ceramics, glasses, polymers, composites and nano-scale materials. A large number of Scientists in Asia are engaged in research in solid state ionic materials and devices and since 1988. The Asian Society for solid state ionics has played a key role in organizing a series of bi-ennial conferences on solid state ionics in different Asian countries. The contributions in this volume were presented at the 10th conference in the series organized by the Postgraduate Institute of Science (PGIS) and the Faculty of Science, University of Peradeniya, Sri Lanka, which coincided with the 10th Anniversary of the Postgraduate Institute of Science (PGIS). The topics cover solid state ionic materials as well as such devices as solid state batteries, fuel cells, sensors, and electrochromic devices. The aspects covered include theoretical studies and modeling, experimental techniques, materials synthesis and characterization, device fabrication and characterization.

In The Beginner's Guide to Winning the Nobel Prize, Doherty recounts his unlikely path to becoming a Nobel Laureate. Beginning with his humble origins in Australia, he tells how he developed an interest in immunology and describes his award-winning, influential work with Rolf Zinkernagel on T-cells and the nature of immune defense. In prose that is at turns amusing and astute, Doherty reveals how his nonconformist upbringing, sense of being an outsider, and search for different perspectives have shaped his life and work. Doherty offers a rare, insider's look at the realities of being a research scientist. He lucidly explains his own scientific work and how research projects are selected, funded, and organized; the major problems science is trying to solve; and the rewards and pitfalls of a career in scientific research. For Doherty, science still plays an important role in improving the world, and he argues that scientists need to do a better job of making their work more accessible to the public. Throughout the book, Doherty explores the stories of past Nobel winners and considers some of the crucial scientific debates of our time, including the safety of genetically modified foods and the tensions between science and religion. He concludes with some "tips" on how to win a Nobel Prize, including advice on being persistent, generous, and culturally aware, and he stresses the value of evidence. The Beginner's Guide to Winning the Noble Prize is essential reading for anyone interested in a career in science.

Mentioned as the second prize area in his will, Chemistry was the most important science for Alfred Nobel's own work. The development of Nobel's inventions as well as the industrial processes he employed were based upon chemical knowledge. This volume is a collection of the Nobel lectures delivered by the prizewinners, together with their biographies and the presentation speeches for the period 2006 2010. Each Nobel lecture is based on the work for which the laureate was awarded the prize. List of prizewinners and their award citations: (2006) Roger D Kornberg for his studies of the molecular basis of eukaryotic transcription; (2007) Gerhard Ertl for his studies of chemical processes on solid surfaces; (2008) Osamu Shimomura, Martin Chalfie and Roger Y Tsien for the discovery and development of the green fluorescent protein, GFP; (2009) Venkatraman Ramakrishnan, Thomas A Steitz and Ada E Yonath for studies of the structure and function of the ribosome; (2010) Richard F Heck, Ei-ichi Negishi and Akira Suzuki for palladium-catalyzed cross couplings in organic synthesis.

Piezo Channels, Volume 79, the latest volume in the Current Topics in Membranes series provides the necessary membrane research to assist readers in discovering the current state of a particular field and future directions. New chapters in the updated volume include A Tour de Force: The Discovery, Properties, and Function of Piezo Channels, Piezo1 Channels in Vascular Development and the Sensing of Shear Stress, the Origin of the Force: The Force-From-Lipids Principle Applied to Piezo Channels, Genetic Diseases of PIEZO1 and PIEZO2 Dysfunction, and The Structural Basis for Sensing by the Piezo1 Protein. Users of this series will find an up-to-date presentation of the current knowledge in the field of Piezo Channels. - Written by leading experts in the field - Contains original material, both textual and illustrative, that make it a very relevant reference - Presented in a very comprehensive manner - Ideal reference for both researchers in the field and general readers who will find this book to be relevant and up-to-date