NMR of Proteins and Nucleic Acids

NMR of Proteins and Nucleic Acids
Author :
Publisher : Wiley-Interscience
Total Pages : 330
Release :
ISBN-10 : UOM:39015010146218
ISBN-13 :
Rating : 4/5 (18 Downloads)

Synopsis NMR of Proteins and Nucleic Acids by : Kurt Wüthrich

Lists of tables. The foundations: structure and NMR of biopolymers. Resonance assignments and structure determination in proteins. Resonance assignments and structure determiantion in nucleic acids. With NMR to biopolymer conformation and beyond.

NMR in Biological Research

NMR in Biological Research
Author :
Publisher : Elsevier Science & Technology
Total Pages : 379
Release :
ISBN-10 : 0720403898
ISBN-13 : 9780720403893
Rating : 4/5 (98 Downloads)

Synopsis NMR in Biological Research by : Kurt Wüthrich

Isotope labeling in Biomolecular NMR

Isotope labeling in Biomolecular NMR
Author :
Publisher : Springer Science & Business Media
Total Pages : 219
Release :
ISBN-10 : 9789400749542
ISBN-13 : 9400749546
Rating : 4/5 (42 Downloads)

Synopsis Isotope labeling in Biomolecular NMR by : Hanudatta S. Atreya

NMR spectroscopy has undergone a revolution in recent years with the advent of several new methods overcoming the problems of sensitivity and resolution. Recent developments in biotechnology have made it easier and economical to introduce 13C, 15N and 2H into proteins and nucleic acids. At the same time, there has been an explosion in the number of NMR experiments that utilize such isotope labeled samples. Thus, a combination of isotopic labeling and multidimensional, multinuclear NMR has opened up new avenues for structural studies of proteins, nucleic acids and their complexes. This book will focus on recent developments in isotope labeling methods for structural studies of small molecules, peptides, proteins and nucleic acids. The aim of the book is to serve as a compendium of isotope labeling for the biomolecular NMR community providing comprehensive coverage of the existing methods and latest developments along with protocols and practical hints on the various experimental aspects. The book will cover a wide range of topics in isotope labeling under one title including emerging areas of metabolonomics and solid state NMR.

Introduction to Biophysical Methods for Protein and Nucleic Acid Research

Introduction to Biophysical Methods for Protein and Nucleic Acid Research
Author :
Publisher : Academic Press
Total Pages : 528
Release :
ISBN-10 : 9780080534985
ISBN-13 : 0080534988
Rating : 4/5 (85 Downloads)

Synopsis Introduction to Biophysical Methods for Protein and Nucleic Acid Research by : Jay A. Glasel

The first of its kind, Introduction to Biophysical Methods for Protein and Nucleic Acid Research serves as a text for the experienced researcher and student requiring an introduction to the field. Each chapter presents a description of the physical basis of the method, the type of information that may be obtained with the method, how data should be analyzed and interpreted and, where appropriate, practical tips about procedures and equipment.Key Features* Modern Use of Mass Spectroscopy* NMR Spectroscopy* Molecular Modeling and Graphics* Macintosh and DOS/Windows 3.x disks

In-cell NMR Spectroscopy

In-cell NMR Spectroscopy
Author :
Publisher : Royal Society of Chemistry
Total Pages : 322
Release :
ISBN-10 : 9781839160936
ISBN-13 : 1839160934
Rating : 4/5 (36 Downloads)

Synopsis In-cell NMR Spectroscopy by : Yutaka Ito

In-cell NMR spectroscopy is a relatively new field. Despite its short history, recent in-cell NMR-related publications in major journals indicate that this method is receiving significant general attention. This book provides the first informative work specifically focused on in-cell NMR. It details the historical background of in-cell NMR, host cells for in-cell NMR studies, methods for in-cell biological techniques and NMR spectroscopy, applications, and future perspectives. Researchers in biochemistry, biophysics, molecular biology, cell biology, structural biology as well as NMR analysts interested in biological applications will all find this book valuable reading.

Dynamics of Proteins and Nucleic Acids

Dynamics of Proteins and Nucleic Acids
Author :
Publisher : Cambridge University Press
Total Pages : 256
Release :
ISBN-10 : 0521356520
ISBN-13 : 9780521356527
Rating : 4/5 (20 Downloads)

Synopsis Dynamics of Proteins and Nucleic Acids by : J. Andrew McCammon

This book is a self-contained introduction to the theory of atomic motion in proteins and nucleic acids. An understanding of such motion is essential because it plays a crucially important role in biological activity. The authors, both of whom are well known for their work in this field, describe in detail the major theoretical methods that are likely to be useful in the computer-aided design of drugs, enzymes and other molecules. A variety of theoretical and experimental studies is described and these are critically analyzed to provide a comprehensive picture of dynamic aspects of biomolecular structure and function. The book will be of interest to graduate students and research workers in structural biochemistry (X-ray diffraction and NMR), theoretical chemistry (liquids and polymers), biophysics, enzymology, molecular biology, pharmaceutical chemistry, genetic engineering and biotechnology.

Biomolecular NMR Spectroscopy

Biomolecular NMR Spectroscopy
Author :
Publisher : IOS Press
Total Pages : 488
Release :
ISBN-10 : 9781607506942
ISBN-13 : 1607506947
Rating : 4/5 (42 Downloads)

Synopsis Biomolecular NMR Spectroscopy by : Andrew J. Dingley

Nuclear Magnetic Resonance (NMR) spectroscopy is the most powerful technique for characterization of biomolecular structures at atomic resolution in the solution state. This timely book, entitled "Biomolecular NMR Spectroscopy," focuses on the latest state-of-the-art NMR techniques for characterization of biological macromolecules in the solid and solution state. The editors, Dr. Andrew Dingley (University of Auckland, New Zealand) and Dr. Steven Pascal (Massey University, New Zealand) have organized the book into four sections, covering the following topics: sample preparation, structure and dynamics of proteins, structure and dynamics of nucleic acids and protein-nucleic acid complexes, and rapid and hybrid techniques--

NMR in Structural Biology

NMR in Structural Biology
Author :
Publisher : World Scientific
Total Pages : 770
Release :
ISBN-10 : 9810223846
ISBN-13 : 9789810223847
Rating : 4/5 (46 Downloads)

Synopsis NMR in Structural Biology by : Kurt Wthrich

The volume presents a survey of the research by Kurt Wthrich and his associates during the period 1965 to 1994. A selection of reprints of original papers on the use of NMR spectroscopy in structural biology is supplemented with an introduction, which outlines the foundations and the historical development of the use of NMR spectroscopy for the determination of three-dimensional structures of biological macromolecules in solution. The original papers are presented in groups highlighting protein structure determination by NMR, studies of dynamic properties and hydration of biological macromolecules, and practical applications of the NMR methodology in fields such as enzymology, transcriptional regulation, immunosuppression and protein folding.

NMR Spectroscopy

NMR Spectroscopy
Author :
Publisher : John Wiley & Sons
Total Pages : 842
Release :
ISBN-10 : 9783527674770
ISBN-13 : 3527674772
Rating : 4/5 (70 Downloads)

Synopsis NMR Spectroscopy by : Harald Günther

Nuclear magnetic resonance (NMR) spectroscopy is one of the most powerful and widely used techniques in chemical research for investigating structures and dynamics of molecules. Advanced methods can even be utilized for structure determinations of biopolymers, for example proteins or nucleic acids. NMR is also used in medicine for magnetic resonance imaging (MRI). The method is based on spectral lines of different atomic nuclei that are excited when a strong magnetic field and a radiofrequency transmitter are applied. The method is very sensitive to the features of molecular structure because also the neighboring atoms influence the signals from individual nuclei and this is important for determining the 3D-structure of molecules. This new edition of the popular classic has a clear style and a highly practical, mostly non-mathematical approach. Many examples are taken from organic and organometallic chemistry, making this book an invaluable guide to undergraduate and graduate students of organic chemistry, biochemistry, spectroscopy or physical chemistry, and to researchers using this well-established and extremely important technique. Problems and solutions are included.