In this issue of Clinics in Chest Medicine, Guest Editors Harold R Collard, Luca Richeldi, and Kerri A. Johannson bring their considerable expertise to the topic of Next-generation Interstitial Lung Disease. - Provides concise and comprehensive coverage of the issues physicians face every day. - Presents the latest information on a timely, focused topic under the leadership of experienced editors in the field.

In this issue of Clinics in Chest Medicine, Guest Editors Harold R Collard, Luca Richeldi, and Kerri A. Johannson bring their considerable expertise to the topic of Next-generation Interstitial Lung Disease. Provides concise and comprehensive coverage of the issues physicians face every day. Presents the latest information on a timely, focused topic under the leadership of experienced editors in the field.

The guest editors for this issue, Talmadge King, Harold Collard, celebrated pulmonary specialists from UCSF, and Luca Richeldi, renowned visiting professor to UCSF from University of Modena, Italy, bring together a state-of-the-art issue on the important topic of Interstitial Lung Diseases (ILD). This comprehensive issue reviews the approach to diagnosis of ILD, radiology if ILD, pathology of ILD. Idiopathic pulmonary fibrosis is discussed, including phenotypes and comorbidities, acute exacerbation and accelerated decline, management, and pathobiology of novel approaches to therapy. Connective Tissue ILD, Chronic Hypersensitivity Pneumonitis, familial ILD and smoking-related ILD, and non-specific interstitial pneumonia are reviewed. In the final article, lung transplantation is discussed.

This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.

Based on careful analysis of burden of disease and the costs ofinterventions, this second edition of 'Disease Control Priorities in Developing Countries, 2nd edition' highlights achievable priorities; measures progresstoward providing efficient, equitable care; promotes cost-effectiveinterventions to targeted populations; and encourages integrated effortsto optimize health. Nearly 500 experts - scientists, epidemiologists, health economists,academicians, and public health practitioners - from around the worldcontributed to the data sources and methodologies, and identifiedchallenges and priorities, resulting in this integrated, comprehensivereference volume on the state of health in developing countries.

SPECIAL OFFER! SAVE WHEN YOU PURCHASE HARRISON’S PRINCIPLES OF INTERNAL MEDICINE, 19e ALONG WITH THE COMPANION HARRISON’S MANUAL! This dollar-saving Harrison’s bundle includes these two great resources: Harrison’s Principles of Internal Medicine, Nineteenth Edition Through six decades, no resource has matched the authority, esteemed scholarship, and scientific rigor of Harrison's Principles of Internal Medicine. Capturing the countless advances and developments across the full span of medicine, the 19th edition of Harrison’s provides a complete update of essential content related to disease pathogenesis, clinical trials, current diagnostic methods and imaging approaches, evidence-based practice guidelines, and established and newly approved treatment methods. Here are just a few of the outstanding features of the Nineteenth Edition: •Presented in two volumes: Volume 1 is devoted to foundational principles, cardinal manifestations of disease and approach to differential diagnosis; Volume 2 covers disease pathogenesis and treatment •NEW chapters on important topics such as Men’s Health, The Impact of Global Warming on Infectious Diseases, Fatigue, and many more •Critical updates in management and therapeutics in Hepatitis, Coronary Artery Disease, Ebola Virus Disease, Multiple Sclerosis, Diabetes, Hypertension, Deep Vein Thrombosis and Pulmonary Embolism, Acute and Chronic Kidney Disease, Inflammatory Bowel Disease, Lipoprotein Disorders, HIV and AIDS, and more. •Increased number of the popular Harrison’s clinical algorithms; clinically relevant radiographic examples spanning hundreds of diseases; clinical-pathological images in full color; crystal clear, full color drawings and illustrations and helpful tables and summary lists that make clinical application of the content faster than ever •Access to outstanding multi-media resources including practical videos demonstrating essential bedside procedures, physical examination techniques, endoscopic findings, cardiovascular findings, and more The package also includes..... Harrison’s Manual of Medicine, Nineteenth Edition Harrison’s Manual of Medicine is a concise, bedside resource derived from content found in Harrison’s Principles of Internal Medicine, Nineteenth Edition. Perfect for use at the point of care, the Manual presents clinical information covering key aspects of the diagnosis, clinical manifestations, and treatment of the major diseases that are likely to be encountered in medical practice. Presented in full color and incorporating an efficient blend of succinct text, bullet points, algorithms, and tables Harrison’s Manual of Medicine, Nineteenth Edition covers every area of clinical medicine, including: • Etiology and Epidemiology • Clinically Relevant Pathophysiology • Signs and Symptoms • Differential Diagnosis • Physical and Laboratory Findings • Therapeutics • Practice Guidelines

Hyperkinetic movement disorders comprise a range of diseases characterized by unwanted and uncontrollable, or poorly controllable, involuntary movements. The phenomenology of these disorders is quite variable encompassing chorea, tremor, dystonia, myoclonus, tics, other dyskinesias, jerks and shakes. Discerning the underlying condition can be very difficult given the range and variability of symptoms. But recognizing the phenomenology and understanding the pathophysiology are essential to ensure appropriate treatment. Hyperkinetic Movement Disorders provides a clinical pathway for effective diagnosis and management of these disorders. The stellar international cast of authors distils the evidence so you can apply it into your practice. The judicious use of diagnostic criteria algorithms rating scales management guidelines Provides a robust framework for clear patient management. Throughout the text, QR codes* provide smartphone access to case-study videos of hyperkinetic symptoms. Purchase includes an enhanced Wiley Desktop Edition.* This is an interactive digital version featuring: all text and images in fully searchable form integrated videos of presentations View a sample video: www.wiley.com/go/albanese highlighting and note taking facilities book marking linking to additional references Hyperkinetic Movement Disorders provides you with the essential visual and practical tools you need to effectively diagnose and treat your patients. *Full instructions for using QR codes and for downloading your digital Wiley DeskTop Edition are inside the book.

Cardiovascular, respiratory, and related conditions cause more than 40 percent of all deaths globally, and their substantial burden is rising, particularly in low- and middle-income countries (LMICs). Their burden extends well beyond health effects to include significant economic and societal consequences. Most of these conditions are related, share risk factors, and have common control measures at the clinical, population, and policy levels. Lives can be extended and improved when these diseases are prevented, detected, and managed. This volume summarizes current knowledge and presents evidence-based interventions that are effective, cost-effective, and scalable in LMICs.

Popular for its easy-to-use format, Felson’s Principles of Chest Roentgenology remains the must-have primer of chest radiology. With the inclusion of the latest imaging approaches and terminology, its unique programmed learning approach —presented in a highly interactive style—demystifies reading and interpreting radiologic images. High-quality images and diagrams are accompanied by multiple-choice review questions to reinforce key concepts. Additional online images plus self-assessment tests help you sharpen your skills and build confidence! "A must for anyone who fancies him/herself as a competent general radiologist." Reviewed by: John Reid, Borders General Hospital on behalf of RAD Magazine, December 2015 Quickly grasp the radiology fundamentals you need to know-including basic science, image interpretation, and terminology-with the popular "programmed learning" approach, which promotes fast learning and reference. Discern the nuances between modalities by comparing CT and MR images as well as traditional radiographs. View detailed clinical images covering all the image types you'll see on the boards including digital quality radiographs and an introduction of PET imaging, plus more advanced imaging such as CT and MRI than ever before. Test your skills and simulate the exam experience with updated content aligned with the new MCQ-format Board exam for easy preparation and review. Benefit the from more robust interactive offerings in an e-book format-with easy-to-access quizzes and board questions provided online. Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, references, and videos from the book on a variety of devices.