New Horizons in Natural Compound Research provides the latest updates in natural compound research (plant, microbes, algae, fungi) and their novel applications in health, agriculture and environment. The book gives recent advances in the extraction of natural compounds, cutting-edge approaches for natural compound purifications, and emerging trends in natural compound screening and identification. In addition, it provides a detailed explanation of the databases and libraries of natural compounds, as well as their significance. Sections focus on research and multidisciplinary practical techniques of natural product research, encouraging young scientists to pursue unique research while also generating strong research ideas. From a future perspective, this book acts as a guide to identify potential areas and new research opportunities in the field of natural products and their service towards human beings, animals and the environment. - Provides a one–stop solution for concepts, cutting-edge techniques, methods, and novel applications of natural products in health and the environment - Focuses on current gaps in natural product research, as well as methodologies and techniques to assist researchers in resolving existing challenges and speeding up the pace of drug discovery from natural sources - Highlights new avenues of natural product research - Contains contributions from well-experienced researchers from academia, research institutes and top-notch young scientists from industry

Sustainable Management of Agro-Food Waste: Fundamental Aspects and Practical Applications provides insights into the latest approaches for optimizing waste produced by these industries. Bioconversion of agro-food waste is a significant concern for maintaining the ecosystem. This book covers current research into the production of a variety of bioactive compounds, bioenergy resources, and nanomaterials using potential microbes associated widely with the industry's waste. With primary focus on the microbial enzymes, secondary metabolites, single cell protein, bioethanol, biohydrogen, bio-fortified compost, bioelectricity, and nanomaterial's, the book presents a range of biotechnological approaches. Sections describe the application of microbial niches in waste recycling and renewable energies like biofuel, plant enzymes, and hormones for different agriculture and allied sectors. With recent advancements in the synthesis of bioactive compounds, bioenergy, and nanomaterials and the discovery of their agriculture, environmental and biomedical applications, it is expected that these methods will be applied at a large scale for industrial application in different sectors. Policies required for the agro-food waste management and option for their utilization are also discussed, along with the sources of their generation. - Presents the foundation of agro-food waste management, including green nanotechnology - Includes multiples management techniques and their potential benefits - Explores the proper mechanisms of synthesis for value-added materials and products for use in bioenergy and biofuel

Marine Molecules from Algae and Cyanobacteria: Extraction, Purification, Toxicology and Applications addresses biomolecules, their roll in living organism, structure elucidation, sources, important characteristics and their industrial applications for educational (academic) and industrial purposes. The book covers all methodologies used in the search of marine natural products, including screening of marine molecules by chemical methods like HPLC, LC-MS/MS, and more. These chemical compounds range from small molecules and enzymes to highly complex secondary metabolites that show bioactivities in physiological systems. Many of these compounds are not commercially available, so the isolation methods of these molecules from microalgae, seaweeds and cyanobacteria is challenging. Because of the complexity of their structure, the total synthesis has been shown to be difficult. Developing protocols to obtain reference standards from natural sources have shown satisfactory results in the chemical industry. The marine environment is a rich but underexploited source of commercially interesting natural products with different applications. Several marine organisms, such as seaweeds, microalgae, sponges, cyanobacteria, ascidians and fungi are sources of natural valuable molecules. - Provides chronological advancements of marine biomolecules, biochemical reactions, and modern industrial applications in the various fields of science and engineering - Highlights well-established research, technology, and applications on marine biomolecules, moves to their rapidly emerging aspects, and then discusses future research directions - Serves as a valuable reference for scientists, chemists, biochemists, nutritionists, pharmacists, and engineers who are searching for modern design and applications of marine molecules

Human and Animal Microbiome Engineering provides both basic and detailed information about microbiome engineering for the health enhancement of humans and animal populations. The book provides updated information about current research topics in this emerging field, including microbiome gene therapy, engineered probiotics, and smart living biotic machines for the release of therapeutics. The book is divided into 4 sections covering microbiome engineering application with a focus on future perspectives in human health and enhancement; microbiome engineering in human health and disease including real-world case studies; animal microbiome engineering essentials; and microbiome engineering for livestock improvement. This is the perfect reference for researchers and scientists to further explore the relationship between host and microbiome and discover novel ideas about the concepts of microbiome engineering in the health enhancement of humans and animal populations. - Provides information about the basic and advanced topics of microbiome engineering - Offers a customized combination of microbial engineered based therapies to promote human health - Includes hot topics like fecal microbiota transplantation for the control of Cl. difficile infection, next generation probiotics, and probiotic engineered microbiomes

The book is a comprehensive guide that explores the use of artificial intelligence and machine learning in drug discovery and development covering a range of topics, including the use of molecular modeling, docking, identifying targets, selecting compounds, and optimizing drugs. The intersection of Artificial Intelligence (AI) and Machine Learning (ML) within the field of drug design and development represents a pivotal moment in the history of healthcare and pharmaceuticals. The remarkable synergy between cutting-edge technology and the life sciences has ushered in a new era of possibilities, offering unprecedented opportunities, formidable challenges, and a tantalizing glimpse into the future of medicine. AI can be applied to all the key areas of the pharmaceutical industry, such as drug discovery and development, drug repurposing, and improving productivity within a short period. Contemporary methods have shown promising results in facilitating the discovery of drugs to target different diseases. Moreover, AI helps in predicting the efficacy and safety of molecules and gives researchers a much broader chemical pallet for the selection of the best molecules for drug testing and delivery. In this context, drug repurposing is another important topic where AI can have a substantial impact. With the vast amount of clinical and pharmaceutical data available to date, AI algorithms find suitable drugs that can be repurposed for alternative use in medicine. This book is a comprehensive exploration of this dynamic and rapidly evolving field. In an era where precision and efficiency are paramount in drug discovery, AI and ML have emerged as transformative tools, reshaping the way we identify, design, and develop pharmaceuticals. This book is a testament to the profound impact these technologies have had and will continue to have on the pharmaceutical industry, healthcare, and ultimately, patient well-being. The editors of this volume have assembled a distinguished group of experts, researchers, and thought leaders from both the AI, ML, and pharmaceutical domains. Their collective knowledge and insights illuminate the multifaceted landscape of AI and ML in drug design and development, offering a roadmap for navigating its complexities and harnessing its potential. In each section, readers will find a rich tapestry of knowledge, case studies, and expert opinions, providing a 360-degree view of AI and ML’s role in drug design and development. Whether you are a researcher, scientist, industry professional, policymaker, or simply curious about the future of medicine, this book offers 19 state-of-the-art chapters providing valuable insights and a compass to navigate the exciting journey ahead. Audience The book is a valuable resource for a wide range of professionals in the pharmaceutical and allied industries including researchers, scientists, engineers, and laboratory workers in the field of drug discovery and development, who want to learn about the latest techniques in machine learning and AI, as well as information technology professionals who are interested in the application of machine learning and artificial intelligence in drug development.

The Well-Grounded Aviator June 1, 1998: While flying as a passenger, I survived a plane crash with traumatic head injuries and a loss of smell, taste, and sight. August 15, 1999: Went to the Rehabilitation for the Blind in Raleigh to learn all new life skills. June 6, 2000: Became the first and only blind Advanced Ground Instructor (AGI) in the world. June 12, 2000: Received first Guide Dog, Lincoln, from Southeastern Guide Dog Incorporated. October, 2000: Became first and only blind Instrument Ground Instructor (IGI) in the world. December, 2004, graduated from University of North Carolina at Charlotte (UNCC), with Lincoln the Navigator. May, 2007, graduated from Embry-Riddle Aeronautical University (ERAU), with Lincoln the Aviator, became the first and only blind graduate student in their 82 year history, and graduated with distinction. June 1, 2007: Nine year anniversary of the accident, began doctoral degree in business administration with a specialization in aeronautical safety, online at Northcentral University. January 20, 2009: Jet, my second Guide Dog came into my life from Guide Dog Foundation. March 1, 2010: Began work with the FAA as an Aviation Safety Analyst with the Commercial and General Aviation Branch, AFS-800, at Headquarters in Washington, DC. August 1, 2014: Married Robin at Graceland, in Elvis’s Chapel in the Woods. July 5, 2017: Dissertation completed and gave oral defense of: “The Relationship between Pilot Attitudes and the execution of Flight Safety Checklists”, to become Dr. Hyde. July 30, 2018, Bravo, third Guide dog received from Southeastern Guide Dog Incorporated. ERAU’s first president, Jack R. Hunt, had a famous saying, “For most people, the sky is the limit. But for those who love aviation, the sky is home.” For me, the sky is home, and I will always want to be a part of flying the friendly skies.

Environmental sustainability practice and research have advanced over the past decade from novelty to near-mainstream status today. During this environmentally critical time period, sustainability practitioner techniques, such as environmental, energy and social auditing, other sustainability information and related systems, and a wide variety of environmental sustainability approaches have been developed, improved and institutionalised, advancing both the practice and research of environmental sustainability management and policy. However, academics and practitioners in the sustainability field still have widely differing perspectives on what a sustainable organisation is or might be, but seldom take the opportunity to share these respective sustainability visions, let alone the multiple ways to achieve them. New Horizons in Research on Sustainable Organisations is intended to bridge this gap between academics and practitioners with cutting-edge research from both groups on progress towards sustainability. After working on sustainability-related projects involving other academics, both research- and practitioner-oriented graduate students, consultants, managers and activists, the lead co-editors of this volume saw the need to encourage information exchanges among differing networks of sustainability stakeholders to create a pathway for researchers and practitioners in the general area of organisations and the natural environment to address issues of common interest. There are many networks in the general subject area, but the cross-pollination of ideas between academics and practitioners remains sketchy. New Horizons in Research on Sustainable Organisations is intended to present and encourage such cross-pollination. The chapters in this volume are presented in three subsets, generally proceeding from the most "macro" to the most "micro" in terms of perspective and applicability. However, this arbitrary division belies the integration from macro through meso (or mid-range) to micro levels that is apparent in these studies. Macro approaches typically include wider geographic scopes, greater numbers of stakeholders, and more complex explanatory factors than micro approaches. Each chapter adopts one or more particular sustainability world-view and then grounds these and the other chapter elements within actual organisations. Therefore, the reader is advised to envision not a one-dimensional continuum but rather a circle in which the macro view both feeds back and feeds forward to the micro view. This volume addresses a number of intriguing and important sustainable organisation phenomena such as multiple sustainable development perspectives, changing environmental politics, environmental management systems variations, voluntary environmental programme performance, complex adaptive systems, and environmental technology development. Additionally, several models are suggested, such as cultivation, capabilities and business ecology frameworks.

This book outlines comprehensive information on the global trends, policies, research priorities and frontier innovations made in the research domain of breeding, biotechnology, biofortification and quality enhancement of wheat and barley. With contributions by international group of leading wheat and barley researchers, this book offers data-based insights along with a holistic view of the subject and serve as a vital resource of information for scientists engaged in breeding future high-yielding biofortified varieties. It catalogs both conventional as well as modern tools for gene identification and genome editing interventions for enhancing the yield, grain quality, disease and pest resistance, nutrient-use efficiency and abiotic stress tolerance. The prospects of processing high quality wheat end-products with long term storage and high nutritional quality are also discussed. This book is of interest to teachers, researchers, molecular breeders, cereal biochemists and biotechnologist, policymakers and professionals working in the area of wheat and barley research, food and cereal industry. Also, the book serves as an additional reading material for the undergraduate and graduate students of agriculture and food sciences. National and international agricultural scientists, policy makers will also find this book to be a useful read. Volume 2 of New Horizons in Wheat and Barley Research covers topics in crop protection and resource management.

This volume focuses on antibiotics research, a field of topical significance for human health due to the worrying increase of nosocomial infections caused by multi-resistant bacteria. It covers several basic aspects, such as the evolution of antibiotic resistance and the influence of antibiotics on the gut microbiota, and addresses the search for novel pathogenicity blockers as well as historical aspects of antibiotics. Further topics include applied aspects, such as drug discovery based on biodiversity and genome mining, optimization of lead structures by medicinal chemistry, total synthesis and drug delivery technologies. Moreover, the development of vaccines as a valid alternative therapeutic approach is outlined, while the importance of epidemiological studies on important bacterial pathogens, the problems arising from the excessive use of antibiotics in animal breeding, and the development of innovative technologies for diagnosing the “bad bugs” are discussed in detail. Accordingly, the book will appeal to researchers and clinicians alike.