Current data and trends in morbidity and mortality for the sub-Saharan Region as presented in this new edition reflect the heavy toll that HIV/AIDS has had on health indicators, leading to either a stalling or reversal of the gains made, not just for communicable disorders, but for cancers, as well as mental and neurological disorders.

This novel title explores the central and peripheral nervous system in health and disease. By first establishing a fundamental basic science knowledge about the cellular elements of the nervous system, the reader is then presented with clinical cases in a pathophysiologic manner, as exemplified in unifying Guillain Barre and Multiple Sclerosis in one chapter on Demyelinating Disease. The reader is encouraged to adopt a systematic approach of sorting out neurologic problems he or she may face in clinical practice by identifying time and space factors based on the age of a patient. High quality illustrations for each case are included in the book along with novel three-dimensional reconstructions of MR, PET, and CT data whenever possible. Developed largely for medical students as an introduction to the clinical neurosciences, for neurology residents, and for others doing graduate level neuroscience study, Neurology - A Modern, Pathophysiologic Approach to the Diagnosis and Treatment of Neurologic Disease will also be of significant interest to the established neurologist as a comprehensive, up-to-date reference.

Mental, neurological, and substance use disorders are common, highly disabling, and associated with significant premature mortality. The impact of these disorders on the social and economic well-being of individuals, families, and societies is large, growing, and underestimated. Despite this burden, these disorders have been systematically neglected, particularly in low- and middle-income countries, with pitifully small contributions to scaling up cost-effective prevention and treatment strategies. Systematically compiling the substantial existing knowledge to address this inequity is the central goal of this volume. This evidence-base can help policy makers in resource-constrained settings as they prioritize programs and interventions to address these disorders.

This single-volume reference covers the natural course, treatment, and management of all neurological diseases affecting the brain, spinal cord nerves and muscles. This comprehensive text reference seeks to assist physicians with treatment by providing an easy-to-use compendium covering the treatment and management of all neurological diseases along with details on the natural course of these diseases. Organized for ease of use and quick reference, each chapter presents a neurological disorder or key symptoms and systematically discusses the clinical syndrome and differential diagnosis, natural course, principles of therapy, and practical management of each. Covers wide range of neurological conditions and potential treatments, including the evidence for and against each treatment Describes the spontaneous course of neurological diseases along with discussion of the management of different stages and variants of a disorder Presents special situations and exceptional cases in which alternative therapies should be considered

This concise text delivers a basic introduction to neurology and is designed for use by medical students during their rotation in neurology and related disciplines. Updated and expanded, this second edition follows the same order as the first, starting with how to approach a patient with a neurologic problem followed by the latest information on the phenomenology, pathophysiology and symptoms of common adult and pediatric neurologic diseases. Supplementing the learning experience are clinical cases that begin each chapter and videos of examples ranging from how to perform the normal neurologic exam to abnormal exam findings. Easy-to-read and richly illustrated, Fundamentals of Neurologic Disease, 2nd Edition is an invaluable resource for anyone seeking to learn the fundamentals of neurology.

Movement disorders - ranging from parkinsonism to a variety of hyperkinetic disorders, such as tremors, dystonic, chorea and myoclonus - can be the presenting or a prominent clinical feature in a broad spectrum of systemic conditions such as endocrine and metabolic disorders, autoimmune diseases, infections, intoxications, tumors and pareneoplastic syndromes, stroke and multiple sclerosis. The resulting clinical scenarios can be confusing and difficult to interpret by internists, generalists and neurologists. Movement Disorders in Neurologic and Systemic Disease provides comprehensive coverage of the most common movement disorders seen in systemic and general neurologic disease, as well as differential diagnostic and therapeutic algorithms. The chapters are written by internationally recognized experts and more than 50 illustrative videos highlight the phenomenology of some of the movement disorders and provide a useful 'bed-side' diagnostic tool. This book is a valuable resource for neurologists, physiatrists, psychiatrists, internists, primary care physicians and trainees in medicine and neurology.

This comprehensive text summarizes what is known about the myriad of different neurological conditions that cause dysfunction of communication, swallowing, and breathing as it relates to the upper aerodigestive tract. It serves to provide clinicians and scientists, at all levels of experience, a practical and thorough review of these diseases, their management, and frontiers in science. Chapters are written by experts in these conditions from a broad spectrum of medical specialties in order to create a book that is inclusive of diagnostic and therapeutic considerations that clinicians should think about when caring for patients with these conditions. Neurologic and Neurodegenerative Diseases of the Larynx will be an instrumental resource in guiding clinicians to better recognize the subtle and not so subtle voice, swallowing, and airway manifestations of these diseases, and improve management of patient symptoms and concerns in order to maximize both quality of life and longevity. It will aide otolaryngologists, laryngologists, neurologists, speech language pathologists, and other allied health care professionals in developing a more efficient, evidence-based, patient-focused, and multi-specialty approach to managing these complex and challenging patients.

This comprehensive guide thoroughly covers all aspects of neuropalliative care, from symptom-specific considerations, to improving communication between clinicians, patients and families. Neuropalliative Care: A Guide to Improving the Lives of Patients and Families Affected by Neurologic Disease addresses clinical considerations for diseases such as dementia, multiple sclerosis, and severe acute brain injury, as well discussing the other challenges facing palliative care patients that are not currently sufficiently met under current models of care. This includes methods of effective communication, supporting the caregiver, how to make difficult treatment decisions in the face of uncertainty, managing grief, guilt and anger, and treating the pain itself. Written by leaders in the field of neuropalliative care, this book is an exceptional, well-rounded resource of neuropalliative care, serving as a reference for all clinicians caring for patients with neurological disease and their families: neurologists and palliative care specialists, physicians, nurses, chaplains, social workers, as well as trainees in these areas.

Sleep and Neurologic Disease reviews how common neurologic illnesses, such as Parkinson's Disease and Alzheimer's dementia impact sleep. In addition, the book discusses how common primary sleep disorders influence neurologic diseases, such as the relationship between obstructive sleep apnea and stroke, as well as their association with various primary headache disorders and epilepsy syndromes. The utilization of sleep technology, such as polysomnography, multiple sleep latency testing, actigraphy, laboratory and CSF testing is also covered. The book is written for the practicing neurologist, sleep physician, neuroscientist, and epidemiologist studying sleep. Reviews how common neurological illnesses impact sleep and the impact sleep disorders have on neurologic disease Up-to-date, comprehensive overview written for practicing neurologists, sleep physicians, neuroscientists, and epidemiologists Includes informative discussions on sleep physiology, circadian rhythms, sleep and stroke, and treatment options for neurologists

Although there are several gaps in understanding the many issues related to neurological disorders, we know enough to be able to shape effective policy responses to some of the most common. This book describes and discusses the increasing public health impact of common neurological disorders such as dementia, epilepsy, headache disorders, multiple sclerosis, neuroinfections, neurological disorders associated with malnutrition, pain associated with neurological disorders, Parkinson's disease, stroke and traumatic brain injuries. It provides information and advice on public health interventions that may reduce their occurrence and consequences, and offers health professionals and planners the opportunity to assess the burden caused by these disorders. The clear message that emerges is that unless immediate action is taken globally, the neurological burden is likely to become an increasingly serious and unmanageable.