A comprehensive survey of best practice in using diagnostic imaging in acute neurologic conditions. The symptom-based approach guides the choice of the available imaging tools for efficient, accurate, and cost-effective diagnosis. Effective examination algorithms integrate neurological and imaging concepts with the practical demands and constraints of emergency care.

Imaging in Parkinson's Disease provides up-to-date information concerning new applications of brain imaging to the study of Parkinson's disease. Written by experts in the field, the book focuses on structural and functional imaging methodologies that have recently been applied to study the natural history of Parkinson's disease, with emphasis on the development of the major motor manifestations of the illness as well as cognitive impairment and dementia.

Annotation "This is the most comprehensive, current volume on transcranial sonography (TCS) in movement disorders. It is written by an experienced, international group of sonographers who present interpretations of recent research findings and provide recommendations about applying the technique. The volume features many demonstrative images to help explain ultrasound anatomy, the TCS technique, and typical findings in specific movement disorders. Exciting new applications are discussed including early and premotor diagnosis of Parkinson's disease and, the use of TCS for intra- and postoperative position control of deep brain stimulation electrodes. This volume gives insight into this rapidly developing and increasingly applied technique, emphasising the validity of the TCS method, the differential diagnostic capacity of the findings and its supplementary value to other neuroimaging techniques. This is an invaluable resource for clinicians and researchers engaged with movement disorders."--Publisher's description.

This comprehensive reference provides a detailed overview of current concepts regarding the cause of Parkinson's disease-emphasizing the issues involved in the design, implementation, and analysis of epidemiological studies of parkinsonism.

Imaging in Parkinson's Disease provides up-to-date information concerning new applications of brain imaging to the study of Parkinson's disease. Written by experts in the field, the book focuses on structural and functional imaging methodologies that have recently been applied to study the natural history of Parkinson's disease, with emphasis on the development of the major motor manifestations of the illness as well as cognitive impairment and dementia. Individual chapters address the role of imaging in differential diagnosis and in the evaluation of pharmacologic and surgical treatment effects. In-depth discussion of the use of imaging tools to study disease mechanisms is also provided, with emphasis on the roles of neuroinflammation, protein aggregation, and abnormal network organization in parkinsonism. Additionally, the text covers a number of relevant novel topics including recent advances in volumetric and functional MRI, echosonography, dopaminergic and cholinergic neurotransmitter imaging, and applications to experimental interventions such as gene therapy and transplantation.Covering a wide range of subjects and beautifully illustrated, Imaging in Parkinson's Disease is a valuable reference for neurologists, neurosurgeons and neuropsychologists, and a helpful resource for students engaged in postgraduate biomedical and clinical training.

A comprehensive review of what is known not only about the cause and treatment of atypical parksonian disorders, but also the issues that clinicians, researchers, patients, and caregivers face in dealing with them. The authors cover the basic science (history, epidemiology, genetics, pathology, nosology, computer modeling, and animal models), detailed clinical and laboratory assessments, and available diagnostic tools, including neuropsychiatric, neurologic, neuropsychologic, speech, electrophysiologic, and imaging evaluations. Current and future therapeutic approaches are also detailed, along with extensive discussions about future research directions.

Neuroimaging in Parkinson's Disease and Related Disorders discusses the advances of molecular, structural and functional neuroimaging techniques associated with the etiology, pathophysiology, effects and complications of novel therapies in Parkinson's and related disorders. With new neuroimaging methodologies emerging over the past five years, this book provides a comprehensive overview of new technologies and research. Sections discuss the biomarker value of neuroimaging of the brain to understand disease progression in vivo in actual patients with Parkinson's disease and related disorders. Readers will be updated on in vivo pathology and pathophysiology in Parkinson's disease and in a number of related disorders. Also discussed is the association between clinical symptoms, clinical progression, and molecular, structural, and functional changes in the brain of patients with Parkinson's disease and related disorders. - Comprehensive overview of biomarker value of neuroimaging of the brain to understand disease progression in vivo in actual patients with Parkinson's disease and related disorders - Helps readers understand the in vivo pathology and pathophysiology in Parkinson's disease and in a number of related disorders - Discusses the association between clinical symptoms, clinical progression, and molecular, structural, and functional changes in the brain of patients with Parkinson's and related disorders

Imaging in Movement Disorders: Imaging in Atypical Parkinsonism and Familial Movement Disorders, Volume 142, addresses the use of imaging modalities across the spectrum of movement disorders and dementias. Over the last decades, advances in neuroimaging tools have played a pivotal role in expanding our understanding of disease aetiology and pathophysiology, identifying biomarkers to monitor disease progression, aiding differential diagnosis and in the identification of novel targets for therapeutic intervention. This updated volume covers PET Molecular Imaging in Atypical Parkinsonism, SPECT Molecular Imaging in Atypical Parkinsonism, Structural MRI in Atypical Parkinsonism, Functional MRI in Atypical Parkinsonism, and more. Offers a complete review of the applications of neuroimaging tools in Atypical Parkinsonism, familial Parkinson’s disease and Huntington’s disease Discusses the role of neuroimaging modalities, including SPECT, PET, and structural and functional MRI Includes sections on potential clinical applications and future directions