Neurobiology of the Locus Coeruleus

Principles and Practice of Movement Disorders provides the complete, expert guidance you need to diagnose and manage these challenging conditions. Drs. Stanley Fahn, Joseph Jankovic and Mark Hallett explore all facets of these disorders, including the latest rating scales for clinical research, neurochemistry, clinical pharmacology, genetics, clinical trials, and experimental therapeutics. This edition features many new full-color images, additional coverage of pediatric disorders, updated Parkinson information, and many other valuable updates. An accompanying Expert Consult website makes the content fully searchable and contains several hundred video clips that illustrate the manifestations of all the movement disorders in the book along with their differential diagnoses. Get just the information you need for a clinical approach to diagnosis and management, with minimal emphasis on basic science. Find the answers you need quickly and easily thanks to a reader-friendly full-color format, with plentiful diagrams, photographs, and tables. Apply the latest advances to diagnosis and treatment of pediatric movement disorders, Parkinson disease, and much more. View the characteristic presentation of each disorder with a complete collection of professional-quality, narrated videos online. Better visualize every concept with new full-color illustrations throughout. Search the complete text online, follow links to PubMed abstracts, and download all of the illustrations, at www.expertconsult.com.

Handbook of in Vivo Neural Plasticity Techniques, Volume 28: A Systems Neuroscience Approach to the Neural Basis of Memory and Cognition gives a comprehensive overview of the current methods and approaches that are used to study neural plasticity from a systems neuroscience perspective. In addition, the book offers in-depth methodological advice that provides the necessary foundation for researchers establishing methods and students who need to understand the theoretical and methodological bases of these approaches. This is the ideal resource for anyone new to the study of cognitive and behavioral neuroscience who seeks an introduction to state-of-the-art techniques. - Offers a comprehensive overview of state-of-the-art approaches to studying neuroplasticity in vivo - Combines discussions of theoretical underpinnings with the methodological and technical aspects necessary to guarantee success - Arranged in a uniform format that clearly and concisely lays out descriptions, methods and the pitfalls of various techniques

This volume covers the dramatic developments that have occurred in basic neuroscience and clinical research in cognitive neurology and dementia. It is based on the clinical approach to the patient, and provides essential knowledge that is fundamental to clinical practice.

This atlas instills a solid knowledge of anatomy by correlating thin-section brain anatomy with corresponding clinical magnetic resonance images in axial, coronal, and sagittal planes. The authors correlate advanced neuromelanin imaging, susceptibility-weighted imaging, and diffusion tensor tractography with clinical 3 and 4 T MRI. Each brain stem region is then analyzed with 9.4 T MRI to show the anatomy of the medulla, pons, midbrain, and portions of the diencephalonin with an in-plane resolution comparable to myelin- and Nissl-stained light microscopy. The book’s carefully organized diagrams and images teach with a minimum of text.

The Handbook of Stress and the Brain focuses on the impact of stressful events on the functioning of the central nervous system; how stress affects molecular and cellular processes in the brain, and in turn, how these brain processes determine our perception of and reactivity to, stressful challenges - acutely and in the long-run. Written for a broad scientific audience, the Handbook comprehensively reviews key principles and facts to provide a clear overview of the interdisciplinary field of stress. The work aims to bring together the disciplines of neurobiology, physiology, immunology, psychology and psychiatry, to provide a reference source for both the non-clinical and clinical expert, as well as serving as an introductory text for novices in this field of scientific inquiry. Part 1 addresses basic aspects of the neurobiology of the stress response including the involvement of neuropeptide, neuroendocrine and neurotransmitter systems and its corollaries regarding gene expression and behavioural processes such as cognition, motivation and emotionality. * Provides an overview of recent advances made in stress research * Includes timely discussion of stress and its effect on the immune system * Presents novel treatment strategies targeting brain processes involved in stress processing and coping mechanisms

New edition building on the success of previous one. Retains core aim of providing an accessible introduction to behavioral neuroanatomy.

The orexin system, discovered in 1998, has emerged as a crucial player in regulating the sleep and wake balance inside our brain. This discovery has sparked a burst of novel and dynamic research on the physiology and pathology of sleep. The Orexin System: Basic Science and Role in Sleep Pathology honors this research and the authors share their ideas and perspectives on the novel developments within the field. The book examines the intricate role of the orexin system in regulating sleep and wake, and its interaction with other wake-regulating systems. The orexin system is dissected at the cellular and molecular level to explore the diversity of the orexin-producing neurons, their projections, and their signaling pathways. Additionally, the book discusses the diseases which are associated with a dysfunctional orexin system, such as narcolepsy, insomnia, substance abuse, and Alzheimer’s disease, and explores the new potential therapeutic applications derived from the burst of research around this fascinating system. This publication is essential reading for neurobiologists, neurologists, psychopharmacologists, sleep researchers, and other researchers and clinical scientists interested in sleep, sleep research, insomnia, and medicine in general.

In den letzten Jahren hat sich der Workshop "Bildverarbeitung für die Medizin" durch erfolgreiche Veranstaltungen etabliert. Ziel ist auch 2020 wieder die Darstellung aktueller Forschungsergebnisse und die Vertiefung der Gespräche zwischen Wissenschaftlern, Industrie und Anwendern. Die Beiträge dieses Bandes - einige davon in englischer Sprache - umfassen alle Bereiche der medizinischen Bildverarbeitung, insbesondere Bildgebung und -akquisition, Maschinelles Lernen, Bildsegmentierung und Bildanalyse, Visualisierung und Animation, Zeitreihenanalyse, Computerunterstützte Diagnose, Biomechanische Modellierung, Validierung und Qualitätssicherung, Bildverarbeitung in der Telemedizin u.v.m.