This book offers a comprehensive review of the most common infectious diseases that affect the nervous system. Written by international experts, it provides a guide to clinicians for accurately diagnosing and treating these challenging syndromes. Organized into six sections, the book presents didactic, up-to-date information on the following topics relating to central nervous system (CNS) infections: diagnosis and evaluation of the patient, bacterial, viral, fungal and mycobacterial infections, disorders of the spinal cord, and a myriad of miscellaneous infections. Chapters specifically reflect and look to resolve the common obstacles clinicians face in the field, such as having unknown etiologies on the majority of CNS infections, insensitive and slow microbiological techniques, an increasing number of immunosuppressed individuals with atypical presentations and pathogens, and a lack of standardized diagnostic algorithms. A complex yet accessible addition to the Current Clinical Neurology Series, Neurological Complications of Infectious Diseases invaluably examines a wide range of infections that have neurological complications and sequelae.

This issue of Neurologic Clinics, edited by Drs. Russell E. Bartt and Allen J. Aksamit, Jr., will focus on Neuro-Infectious Diseases. Topics include, but are not limited to, Acute Community and Nosocomial Meningitis; Viral Encephalitis and Post-infectious Autoimunnity; Spine and spinal cord infections; Chronic meningitis; Manifestations of Herpes Virus Infections in the Nervous System; HIV and Nervous System; Neuroborreliosis; Progressive Multifocal Leukoencephalopathy; Zika Virus and Neurological Disease; Neurocysticercosis; Prion Disease; and Diagnostic Testing of Neurological Infections.

Current data and trends in morbidity and mortality for the sub-Saharan Region as presented in this new edition reflect the heavy toll that HIV/AIDS has had on health indicators, leading to either a stalling or reversal of the gains made, not just for communicable disorders, but for cancers, as well as mental and neurological disorders.

This book provides an in-depth review of knowledge of neurobrucellosis, which remains common despite significant improvements in preventive measures, neuroradiological techniques, and treatment methods. The chapters are organized into five sections, the first three of which address cranial and intracranial brucellosis, spinal brucellosis, and brucellosis of the peripheral portions of the nervous system. The fourth section focuses on laboratory studies in neurobrucellosis, and the closing section is devoted to therapy, encompassing both medical approaches and the surgical procedures used to treat the complications associated with brucellosis involving the spine, brain, and peripheral nerves. Despite the impressive efforts to eradicate the disease, brucellosis still poses a great threat in the Mediterranean Basin, where it originated, as well as in South and Central America, the Caribbean, and Africa. Written and edited by leading international authorities in the field, this comprehensive book will be an ideal up-to-date reference for neurosurgeons, neurologists, and specialists in infectious disease who are seeking either basic or more advanced information on the disease and its diagnosis and treatment.

Mental, neurological, and substance use disorders are common, highly disabling, and associated with significant premature mortality. The impact of these disorders on the social and economic well-being of individuals, families, and societies is large, growing, and underestimated. Despite this burden, these disorders have been systematically neglected, particularly in low- and middle-income countries, with pitifully small contributions to scaling up cost-effective prevention and treatment strategies. Systematically compiling the substantial existing knowledge to address this inequity is the central goal of this volume. This evidence-base can help policy makers in resource-constrained settings as they prioritize programs and interventions to address these disorders.

This issue of Neurologic Clinics, guest edited by Drs. Joseph D. Burns and Anna M. Cervantes-Arslanian, will focus on Neurologic Emergencies. This issue is one of four selected each year by series consulting editor, Dr. Randolph W. Evans. Topics include—but are not limited to—Coma and depressed level of alertness; Post-arrest Neuroprotection; Headache Emergencies; Acute dizziness, vertigo, and unsteadiness; Neuro-ophthalmologic emergencies; Intracerebral hemorrhage; Acute ischemic stroke; Seizures and status epilepticus; Movement disorders emergencies; Neuromuscular respiratory failure; Neuroinfectious disease emergencies; Severe traumatic brain injury; Acute myelopathy; Neuro-oncologic emergencies; Autoimmune neurologic emergencies; Brain herniation and intracranial hypertension; Aneurysmal subarachnoid hemorrhage; Anesthesiology considerations in neurological emergencies; Neurological emergencies during the COVID pandemic; Neurocritical care and the COVID pandemic; and Neurologic Emergencies during Pregnancy.

An essential resource for diagnosis and treatment of stroke patients outside the usual clinical categories.

This issue of Neurologic Clinics, edited by Drs. Patrick Y. Wen and Eudocia Quant Lee, will focus on Neuro-oncology. Topiocs include, but are not limited to, Epidemiology of brain tumors, Molecular pathogenesis of brain tumors, Changes in WHO classification of brain tumors, Neurologic and medical management of brain tumors, Grade 2 and 3 Gliomas, Glioblastoma, Benign brain tumors, Primary CNS lymphoma and neurologic complications of systemic lymphoma, Pediatric brain tumors, Brain metastases, Metastatic complications of cancer, Neurologic complications of radiation therapy, Neurologic complications of systemic anticancer therapies, Neurocognitive complaints in cancer patients, and Paraneoplastic syndromes.

The emergence of HIV disease and AIDS, the reemergence of tuberculosis, and the increased opportunity for disease spread through international travel demonstrate the critical importance of global vigilance for infectious diseases. This volume highlights risk factors for the emergence of microbial threats to health, warns against complacency in public health, and promotes early prevention as a cost-effective and crucial strategy for maintaining public health in the United States and worldwide. The volume identifies infectious disease threats posed by bacteria and viruses, as well as protozoans, helminths, and fungi. Rich in information, it includes a historical perspective on infectious disease, with focuses on Lyme disease, peptic ulcer, malaria, dengue, and recent increases in tuberculosis. The panel discusses how "new" diseases arise and how "old" ones resurge and considers the roles of human demographics and behavior, technology and industry, economic development and land use, international travel and commerce, microbial adaptation and change, and breakdown of public health measures in changing patterns of infectious disease. Also included are discussions and recommendations on disease surveillance; vaccine, drug, and pesticide development; vector control; public education and behavioral change; research and training; and strengthening of the U.S. public health system. This volume will be of immediate interest to scientists specializing in all areas of infectious dieseases and microbiology, healthy policy specialists, public health officials, physicians, and medical faculty and students, as well as anyone interested in how their health can be threatened by infectious diseases.

This important subject of Diagnosis of and Treatment for Neurobehavioral manifestations of neurologic disease is directed by three leaders of this field - Dr. Alizeza Minagar, Dr. Glen Finney, and Dr. Kenneth Heilman. Topics include: Neurobehavioral testing for mental status; Behavioral neurology of vascular neurology; Alzheimer's disease; Frontotemporal dementia; Traumatic brain injury; Parkinsonian Syndromes (e.g., Parkinson's disease, Lewy body dementia, progressive supranuclear palsy, corticobasal disease, multisystem atrophy); Behavioral neurology of multiple sclerosis and autoimmune encephalopathies; Infectious Diseases (Neuro-AIDS, Neurosyphilis, HSV); Neurobehavioral aspects of systemic disease; Neurobehavioral aspects of epilepsy; Behavioral neurology aspects of nutritional deficiencies; Neurobehavioral aspects of mitochondrial disease; and Medicinal-induced behavioral disorders.