Point of care (POC) diagnostic devices are predominantly used for the diagnosis and monitoring of diseases. To make these technologies scalable for manufacturing, user-friendly, inexpensive, sensitive, and rapid, a combination of such devices with nanomaterials is required. This book deals with new emerging fields such as POC technologies and advanced nanotheranostics using nanomaterials and their technologies and applications in diagnosis. In this book, current advances for the application of nanomaterials such as carbon nanotubes, graphene, and magnetic nanoparticles in POC devices and future directions are reviewed. This book: Presents a comprehensive account of needs and challenges of POC diagnostics Describes the fundamentals of rationale of nanomaterials as remarkable building blocks for biosensing Discusses development of critical diagnosis in POC systems Deals with the advantages of nanomaterial-based sensing strategies Illustrates the challenges and breakthroughs of technologies for cost-efficient biosensing platform The book is aimed at researchers and professionals in nanotechnology and biomedical engineering.

"Point-of-care POC diagnostic devices are predominantly used for the diagnosis and monitoring of diseases. To make these technologies scalable for manufacturing, user-friendly, inexpensive, sensitive, and rapid, combination of such devices with nanomaterials is required. This book deals with the new emerging fields such as POC technologies, advanced nanotheranostics using nanomaterials, technologies, and applications in diagnosis. Current advances for the application of nanomaterials such as carbon nanotubes, graphene, and magnetic nanoparticles in POC devices and future directions are reviewed. Presents a comprehensive account of needs and challenges of point-of-care diagnostics. Describes the fundamentals of rationale of nanomaterials as remarkable building block for biosensing. Discusses development of critical diagnosis in point of care systems. Deals with the advantages of nanomaterial-based sensing strategies. Illustrates the challenges and breakthroughs of technologies for cost-efficient biosensing platform. The book is aimed at Researchers and professionals in nanotechnology and biomedical engineering"--

Nanomaterials in Diagnostic Tools and Devices provides a complete overview of the significance of nanomaterials in fabricating selective and performance enhanced nanodevices. It is an interdisciplinary reference that includes contributing subjects from nanomaterials, biosensors, materials science, biomedical instrumentation and medicinal chemistry. This book is authored by experts in the field of nanomaterial synthesis, modeling, and biosensor applications, and provides insight to readers working in various science fields on the latest advancements in smart and miniaturized nanodevices. These devices enable convenient real-time diagnosis of diseases at clinics rather than laboratories, and include implantable devices that cause less irritation and have improved functionality. Research in the field of nanomaterials is growing rapidly, creating a significant impact across different science disciplines and nanotechnology industries. This synthesis and modeling of nanomaterials has led to many technology breakthroughs and applications, especially in medical science. - Provides a distinctive platform for the latest trends in the synthesis of smart nanomaterials for nanodevices in disease diagnostics - Presents a broad range of advancements and applications of lateral-flow nanostrip for point-of-care applications - Examines smart-phone based nanodevices for field-based diagnosis with accurate information - Comprises more than 70 figures and illustrations that will help readers visualize and easily understand the role of nanodevices in the field of nanomedicine - Serves as an ideal reference for those studying smart nanomaterials, biosensors, and nanodevices for real-time and in-situ clinical diagnosis and drug delivery

This book highlights the recent advancement in point-of-care testing (POCT) technologies utilizing ‘smart’ nanomaterials for the analysis of biomarkers related to disease, which includes metabolites, enzymes, proteins, nucleic acids, cancer cells and multidrug-resistant pathogen. The POCT refers to medical diagnostic tests performed near the place and time of patient care. During the recent pandemic of COVID-19, many realized the importance of affordable, rapid and accurate POCT devices and their usefulness to combat the spread of the infection. The chapters in this book describe the emergence of ‘smart’ nanomaterials with unique physical and chemical properties being utilized in POCT devices for immobilizing biorecognition elements and labels for signal generation, transduction and amplification. It showcases the applications of these smart nanomaterials and their superiority in developing point-of-care diagnostics devices in a wide range of applied fields like food industry, agriculture sector, water quality assessment, pharmaceuticals and tissue engineering. It also looks into the challenges associated and future direction of research in this promising field. This book caters as reference book for researches from the field of nanobiotechnology and biomedical sciences who are interested in the development of rapid, affordable and accurate POCT devices.

This book chronicles the role of advanced nanomaterials and surface engineering technologies in the development of point-of-care biosensors for health and environmental monitoring. All aspects of nanomaterial synthesis and characterization, functionalization methods, sensing surface engineering, signal amplification strategies, use of innovative technologies to enhance sensor efficiency and performances, and innovative applications of nanobiosensors to tackle real-life problems are discussed in this book with a focus on optical and electrochemical based sensing. It also covers the detection of infectious diseases and various disease biomarkers, smartphone-based biosensing, and portable diagnostics module developments with a discussion on the working mechanisms of these devices in various domains. The book also illustrates the recent trends in biosensing, and an overview of the challenges and probable solutions for the translation of biosensors from laboratory prototypes to commercial success. ​

Advanced Nanomaterials for Point of Care Diagnosis and Therapy provides an overview of technological and emerging novel trends in how point-of-care diagnostic devices are designed, miniaturized built, and delivered at different healthcare set ups. It describes the significant technological advances in fundamental diagnostic components and recent advances in fully integrated devices designed for specific clinical use. The book covers state-of-the-art fabrication of advances materials with broad spectrum therapeutic applications. It includes drug delivery, biosensing, bioimaging and targeting, and outlines the development of inexpensive, effective and portable in vitro diagnostics tools for any purpose that can be used onsite. Sections also discuss drug delivery, biosensing, bioimaging and targeting and various metal, metal oxide and non-metal-based nanomaterials that are developed, surface modified, and are being explored for diagnosis, targeting, drug delivery, drug release and imaging. The book concludes with current needs and future challenges in the field. Outlines the needs and challenges of point-of-care diagnostics Describes the fundamentals of application of nanomaterials as interesting building blocks for biosensing Overviews the different detection methods offered by using nanomaterials Explains the advantages and drawbacks of nanomaterial-based sensing strategies Describes the opportunities offered by technology as a cost-efficient biosensing platform

Smart Nanodevices for Point-of-Care Applications examines the latest trends on the capabilities of nanomaterials for point-of-care (PoC) diagnostics and explains how these materials can help to strengthen, miniaturize, and improve the quality of diagnostic devices. A thorough explanation of all-in-one nanosmart devices is included, incorporating all of the applications and fundamentals of these smart devices. This book provides practical information on the following: novel and effective smart materials, better-quality health management, effective management of a disease, potential point-of-care devices, and mobile nanosensors. Additional Features Includes in-depth research based collation of the latest trends of smart devices Provides practical information on all-in-one nanosmart devices Explains how nanomaterials can help to strengthen and improve the quality of diagnostic devices Emphasizes the development of smart nanodevices, especially the miniaturization aspect

Functionalized Nanomaterial-Based Electrochemical Sensors: Principles, Fabrication Methods, and Applications provides a comprehensive overview of materials, functionalized interfaces, fabrication strategies and application areas. Special attention is given to the remaining challenges and opportunities for commercial realization of functionalized nanomaterial-based electrochemical sensors. An assortment of nanomaterials has been investigated for their incorporation into electrochemical sensors. For example, carbon- based nanomaterials (carbon nanotube, graphene and carbon fiber), noble metals (Au, Ag and Pt), polymers (nafion, polypyrrole) and non-noble metal oxides (Fe2O3, NiO, and Co3O4). The most relevant materials are discussed in the book with an emphasis on their evaluation of their realization in commercial applications. Application areas touched on include the environment, food and medicine industries. Health, safety and regulation considerations are touched on, along with economic and commercialization trends. - Introduces the principles of nanomaterials for electrochemical sensing applications - Reviews the most relevant fabrication strategies for functionalized nanomaterial-based electrochemical sensing platforms - Discusses considerations for the commercial realization of functionalized nanomaterial-based electrochemical sensors in the environment, food and point-of-care applications

This book gives a comprehensive overview of the recent advancements and developments of rapid diagnostic tests (RDTs) and technologies, which are quite novel approaches and might be used as laboratory bench manual for the rapid diagnosis of the various disease conditions. The book focuses on various aspects and properties of RDTs, point-of-care tests (POCTs), quality control, assurance, calibration, safety, nano-/microfluidic technologies, and fusion with DNA technologies. I hope that this work might increase the interest in this field of research and that the readers will find it useful for their investigations, management, and clinical usage.

This book describes the emerging point-of-care (POC) technologies that are paving the way to the next generation healthcare monitoring and management. It provides the readers with comprehensive, up-to-date information about the emerging technologies, such as smartphone-based mobile healthcare technologies, smart devices, commercial personalized POC technologies, paper-based immunoassays (IAs), lab-on-a-chip (LOC)-based IAs, and multiplex IAs. The book also provides guided insights into the POC diabetes management software and smart applications, and the statistical determination of various bioanalytical parameters. Additionally, the authors discuss the future trends in POC technologies and personalized and integrated healthcare solutions for chronic diseases, such as diabetes, stress, obesity, and cardiovascular disorders. Each POC technology is described comprehensively and analyzed critically with its characteristic features, bioanalytical principles, applications, advantages, limitations, and future trends. This book would be a very useful resource and teaching aid for professionals working in the field of POC technologies, in vitro diagnostics (IVD), mobile healthcare, Big Data, smart technology, software, smart applications, biomedical engineering, biosensors, personalized healthcare, and other disciplines.