A central goal of biology is to decode the mechanisms that underlie the processes of morphogenesis and pattern formation. Concerned with the analysis of those phenomena, this book integrates experimental and theoretical aspects of biology for the construction and investigation of models of complex processes. It offers an interdisciplinary approach to the pattern formation problems and provides a scope of forthcoming integrated biology including experiments and theories.

Pattern Formation in Morphogenesis is a rich source of interesting and challenging mathematical problems. The volume aims at showing how a combination of new discoveries in developmental biology and associated modelling and computational techniques has stimulated or may stimulate relevant advances in the field. Finally it aims at facilitating the process of unfolding a mutual recognition between Biologists and Mathematicians of their complementary skills, to the point where the resulting synergy generates new and novel discoveries. It offers an interdisciplinary interaction space between biologists from embryology, genetics and molecular biology who present their own work in the perspective of the advancement of their specific fields, and mathematicians who propose solutions based on the knowledge grasped from biologists.

What are the relations between the shape of a system of cities and that of fish school? Which events should happen in a cell in order that it participates to one of the finger of our hands? How to interpret the shape of a sand dune? This collective book written for the non-specialist addresses these questions and more generally, the fundamental issue of the emergence of forms and patterns in physical and living systems. It is a single book gathering the different aspects of morphogenesis and approaches developed in different disciplines on shape and pattern formation. Relying on the seminal works of D’Arcy Thompson, Alan Turing and René Thom, it confronts major examples like plant growth and shape, intra-cellular organization, evolution of living forms or motifs generated by crystals. A book essential to understand universal principles at work in the shapes and patterns surrounding us but also to avoid spurious analogies.

Account of the developmental biology of fungi.

This 121st IMA volume, entitled MATHEMATICAL MODELS FOR BIOLOGICAL PATTERN FORMATION is the first of a new series called FRONTIERS IN APPLICATION OF MATHEMATICS. The FRONTIERS volumes are motivated by IMA pro grams and workshops, but are specially planned and written to provide an entree to and assessment of exciting new areas for the application of mathematical tools and analysis. The emphasis in FRONTIERS volumes is on surveys, exposition and outlook, to attract more mathematicians and other scientists to the study of these areas and to focus efforts on the most important issues, rather than papers on the most recent research results aimed at an audience of specialists. The present volume of peer-reviewed papers grew out of the 1998-99 IMA program on "Mathematics in Biology," in particular the Fall 1998 em phasis on "Theoretical Problems in Developmental Biology and Immunol ogy." During that period there were two workshops on Pattern Formation and Morphogenesis, organized by Professors Murray, Maini and Othmer. James Murray was one of the principal organizers for the entire year pro gram. I am very grateful to James Murray for providing an introduction, and to Philip Maini and Hans Othmer for their excellent work in planning and preparing this first FRONTIERS volume. I also take this opportunity to thank the National Science Foundation, whose financial support of the IMA made the Mathematics in Biology pro gram possible.

This reference work provides an comprehensive and easily accessible source of information on numerous aspects of Evolutionary Developmental Biology. The work provides an extended overview on the current state of the art of this interdisciplinary and dynamic scientific field. The work is organized in thematic sections, referring to the specific requirements and interests in each section in far detail. “Evolutionary Developmental Biology – A Reference Guide” is intended to provide a resource of knowledge for researchers engaged in evolutionary biology, developmental biology, theoretical biology, philosophy of sciences and history of biology.

Morphogenesis is the set of processes that generate shape and form in the embryo--an important area within developmental biology. An exciting and up-to-the-minute account of the very latest research into the factors that create biological form, Mechanisms of Morphogenesis, second edition is a text reference on the mechanisms of cell and tissue morphogenesis in a diverse array of organisms, including prokaryotes, animals, plants and fungi. By combining hard data with computer modeling, Mechanisms of Morphogenesis, second edition equips readers with a much broader understanding of the scope of modern research than is otherwise available. The book focuses on the ways in which the genetic program is translated to generate cell shape, to direct cell migration, and to produce the shape, form and rates of growth of the various tissues. Each topic is illustrated with experimental data from real systems, with particular reference to gaps in current knowledge and pointers to future - Includes over 200 four-color figures - Offers an integrated view of theoretical developmental biology and computer modelling with laboratory-based discoveries - Covers experimental techniques as a guide to the reader - Organized around principles and mechanisms, using them to integrate discoveries from a range of organisms and systems

"A concise account of what we know about development discusses the first vital steps of growth and explores one of the liveliest areas of scientific research."--P. [2] of cover.

Topics in Mathematical Modeling is an introductory textbook on mathematical modeling. The book teaches how simple mathematics can help formulate and solve real problems of current research interest in a wide range of fields, including biology, ecology, computer science, geophysics, engineering, and the social sciences. Yet the prerequisites are minimal: calculus and elementary differential equations. Among the many topics addressed are HIV; plant phyllotaxis; global warming; the World Wide Web; plant and animal vascular networks; social networks; chaos and fractals; marriage and divorce; and El Niño. Traditional modeling topics such as predator-prey interaction, harvesting, and wars of attrition are also included. Most chapters begin with the history of a problem, follow with a demonstration of how it can be modeled using various mathematical tools, and close with a discussion of its remaining unsolved aspects. Designed for a one-semester course, the book progresses from problems that can be solved with relatively simple mathematics to ones that require more sophisticated methods. The math techniques are taught as needed to solve the problem being addressed, and each chapter is designed to be largely independent to give teachers flexibility. The book, which can be used as an overview and introduction to applied mathematics, is particularly suitable for sophomore, junior, and senior students in math, science, and engineering.