In Mood Genes, leading psychiatrist and biological researcher Samuel B arondes answers these questions in a way that renders a complex subjec t both exciting and understandable. Focusing on manic depressive illne ss, which affects about one percent of the population and has long bee n known to run in families, Barondes describes the fascinating hunt fo r genes--called mood genes--that influence the inherited vulnerability to severe mood disorders. He builds the compelling story of this hunt on the histories of two families riddled with manic-depression, expla ining what it means to have an inherited predisposition to a severe mo od disorder, how to find the mood genes that are responsible, and what will happen as mood genes are found.

With recent studies using genetic, epigenetic, and other molecular and neurochemical approaches, a new era has begun in understanding pathophysiology of suicide. Emerging evidence suggests that neurobiological factors are not only critical in providing potential risk factors but also provide a promising approach to develop more effective treatment and prevention strategies. The Neurobiological Basis of Suicide discusses the most recent findings in suicide neurobiology. Psychological, psychosocial, and cultural factors are important in determining the risk factors for suicide; however, they offer weak prediction and can be of little clinical use. Interestingly, cognitive characteristics are different among depressed suicidal and depressed nonsuicidal subjects, and could be involved in the development of suicidal behavior. The characterization of the neurobiological basis of suicide is in delineating the risk factors associated with suicide. The Neurobiological Basis of Suicide focuses on how and why these neurobiological factors are crucial in the pathogenic mechanisms of suicidal behavior and how these findings can be transformed into potential therapeutic applications.

Courses in psychological distress and disorders are among the most popular courses in psychology programs, and mood and anxiety disorders are among the most prevalent disorders covered in these classes and encountered by mental health professionals. Although there are books on mood and anxiety disorders, on particular aspects of them, and on their presentation in specific populations, such works do not provide students new to the field with a comprehensive and accessible ready reference for understanding these disorders with respect to their phenomenology, etiology, and treatment, and through an inclusive lens that consistently considers how these symptoms appear and are construed across cultures, addressing societal factors such as race, culture, equity, and oppression. It is hoped that The SAGE Encyclopedia of Mood and Anxiety Disorders will fill this gap, allowing students and other interested readers to become familiar with past and current approaches and theories and to enhance their understanding of the sociocultural factors that affect how we discuss, approach, and treat these types of psychological distress. As such, consideration of sociocultural factors will infuse the three-volume set. The encyclopedia will consist of approximately 450 entries (essays), arranged alphabetically within three volumes.

Neuropsychiatric disorders such as schizophrenia, mood disorders, Alzheimer’s disease, epilepsy, alcoholism, substance abuse and others are one of the most debilitating illnesses worldwide characterizing by the complexity of the causes, and lacking the laboratory tests that may promote diagnostic and prognostic procedures. Recent advances in neuroscience, genomic, genetic, proteomic and metabolomic knowledge and technologies have opened the way to searching biomarkers and endophenotypes, which may offer powerful and exciting opportunity to understand the etiology and the underlying pathophysiological mechanisms of neuropsychiatric disorders. The challenge now is to translate these advances into meaningful diagnostic and therapeutic advances. This book offers a broad synthesis of the current knowledge about diverse topics of the biomarker and endophenotype strategies in neuropsychiatry. The book is organized into four interconnected volumes: “Neuropsychological Endophenotypes and Biomarkers” (with overview of methodological issues of the biomarker and endophenotype approaches in neuropsychiatry and some technological advances), “Neuroanatomical and Neuroimaging Endophenotypes and Biomarkers”, “Metabolic and Peripheral Biomarkers” and “Molecular Genetic and Genomic Markers”. The contributors are internationally and nationally recognized researchers and experts from 16 countries. This four-volume handbook is intended for a broad spectrum of readers including neuroscientists, psychiatrists, neurologists, endocrinologists, pharmacologists, clinical psychologists, general practitioners, geriatricians, health care providers in the field of neurology and mental health interested in trends that have crystallized in the last decade, and trends that can be expected to further evolve in the coming years. It is hoped that this book will also be a useful resource for the teaching of psychiatry, neurology, psychology and mental health.

Parallel to An Unquiet Mind and The Glass Castle, a deeply personal memoir calling for the destigmatization of mental illness

Basic Neurochemistry: Molecular, Cellular and Medical Aspects, a comprehensive text on neurochemistry, is now updated and revised in its Seventh Edition. This well-established text has been recognized worldwide as a resource for postgraduate trainees and teachers in neurology, psychiatry, and basic neuroscience, as well as for graduate and postgraduate students and instructors in the neurosciences. It is an excellent source of information on basic biochemical processes in brain function and disease for qualifying examinations and continuing medical education. - Completely updated with 60% new authors and material, and entirely new chapters - Over 400 fully revised figures in splendid color

This exclusive ebook bundle comprises five practical self-help programmes based on cognitive behavioural therapy (CBT) from the bestselling Overcoming series. Perfect for anyone experiencing problems with low mood or depression and associated problems such as low self-esteem, anger or sleep problems. This is also the perfect resource for therapists. Each book includes: -Case studies -Practical exercises -Monitoring sheets Overcoming Depression - 3rd edition If you suffer from depression you are far from alone. Depression is very common, affecting over 300 million people around the world. Written by Professor Paul Gilbert OBE, internationally recognised for his work on depression, this highly acclaimed self-help book has been of benefit to thousands of people including sufferers, their friends and families, and those working in the medical profession. This fully revised third edition has been extensively updated and rewritten to reflect over ten years of new research on understanding and treating depression, particularly the importance of developing compassionate ways of thinking, behaving and feeling. Overcoming Mood Swings Most people know what it is like to experience high or low spirits. For some individuals, however, emotional extremes can seriously disrupt their lives, either because they happen too frequently or because the mood swings are intense and are accompanied by other symptoms of depression or mania (often referred to as bipolar disorder). This practical self-help guide provides background information on depression and mania and offers tried and tested techniques that will help the reader identify and manage their mood more effectively, and achieve a more stable emotional state. Overcoming Low Self-Esteem A self-help classic, winning acclaim for its practical and user-friendly approach and now recommended on the National Health Service's self-help scheme known as Books on Prescription. This book will aid readers to understand what has caused their low self-esteem and, with this knowledge, break out of the vicious circle of negative self-image, learn the art of self-acceptance and alter their lives for the better. Overcoming Anger and Irritability An invaluable self-help guide to managing a widespread behavioural problem. This is a practical self-help programme for those who find that they are spoiling the lives of both themselves and those around them with their almost constant irritability and flashes of bad temper. It will help the reader understand why such behaviour occurs and what can be done to prevent it. Overcoming Insomnia Extensive research conducted over 25 years has established Cognitive Behavioural Therapy (CBT) as the treatment of choice for insomnia. For the first time, proven CBT principles have been brought together by a world-renowned expert on insomnia in a comprehensive self-help manual. In a clear step-by-step approach, new patterns of relaxation, sleeping and waking are quickly learnt. Based on clinically proven techniques.

The study of emotions has rapidly expanded in recent decades, incorporating interdisciplinary research on the genetic underpinnings and neural mechanisms of emotion. This book offers a comprehensive account of this interdisciplinary field of research, bridging psychology, genetics, and neuroscience.

What causes psychiatric disorders to appear? Are they primarily the result of people's environments, or of their genes? Increasingly, we are told that research has confirmed the importance of genetic influences on schizophrenia, depression, bipolar disord.