This title provides a brief but accurate summary of all the basic ideas, theories, methods, and conspicuous results of structure analysis and molecular modelling of the condensed phases of organic compounds.

Given the enormous interest in surface phenomena in areas ranging from materials science to applications in life science, this volume is a very timely addition to the literature. Emphasis is on surfactants mediating interfacial and molecular aggregation phenomena, and the following topics are reviewed in particular: dissolution rates, equilibrium adsorption, mixing rules, and spreading on a solid surface of surfactants, as well as the role of surfactants in mediating a range of processes, such as the fabrication of various nanomaterials. Written and edited by leading experts, this volume is dedicated to Professor Dinesh O. Shah, one of the pioneers in this field.

Bio-Nanoimaging: Protein Misfolding & Aggregation provides a unique introduction to both novel and established nanoimaging techniques for visualization and characterization of misfolded and aggregated protein species. The book is divided into three sections covering: - Nanotechnology and nanoimaging technology, including cryoelectron microscopy of beta(2)-microglobulin, studying amyloidogensis by FRET; and scanning tunneling microscopy of protein deposits - Polymorphisms of protein misfolded and aggregated species, including fibrillar polymorphism, amyloid-like protofibrils, and insulin oligomers - Polymorphisms of misfolding and aggregation processes, including multiple pathways of lysozyme aggregation, misfolded intermediate of a PDZ domain, and micelle formation by human islet amyloid polypeptide Protein misfolding and aggregation is a fast-growing frontier in molecular medicine and protein chemistry. Related disorders include cataracts, arthritis, cystic fibrosis, late-onset diabetes mellitus, and numerous neurodegenerative diseases like Alzheimer's and Parkinson's. Nanoimaging technology has proved crucial in understanding protein-misfolding pathologies and in potential drug design aimed at the inhibition or reversal of protein aggregation. Using these technologies, researchers can monitor the aggregation process, visualize protein aggregates and analyze their properties. - Provides practical examples of nanoimaging research from leading molecular biology, cell biology, protein chemistry, biotechnology, genetics, and pharmaceutical labs - Includes over 200 color images to illustrate the power of various nanoimaging technologies - Focuses on nanoimaging techniques applied to protein misfolding and aggregation in molecular medicine

The first volume of the ultimate reference on the science and applications of aggregation-induced emission The Handbook of Aggregation-Induced Emission explores foundational and advanced topics in aggregation-induced emission, as well as cutting-edge developments in the field, celebrating twenty years of progress and achievement in this important and interdisciplinary field. The three volumes combine to offer readers a comprehensive and insightful interpretation accessible to both new and experienced researchers working on aggregation-induced emission. In this first volume of three, the editors survey the subject of aggregation-induced emission with a focus on the fundamentals of various branches of the discipline, such as crystallization-induced emission, room temperature phosphorescence, aggregation-induced delayed fluorescence, and more. This book covers the new properties of materials endowed by molecular aggregates. It also includes: A thorough introduction to the mechanistic understanding of the importance of molecular motion to aggregation-induced emission An exploration of the aggregation-induced emission mechanism at the molecular level Practical discussions of aggregation-induced emission from the restriction of double bond rotation at the excited state, and clusterization-triggered emission Perfect for academic researchers working on aggregation-induced emission, this set of volumes is also ideal for professionals and students in the fields of photophysics, photochemistry, materials science, optoelectronic materials, synthetic organic chemistry, macromolecular chemistry, polymer science, and biological sciences.

This two volume set introduces the up-to-date high-tech applications of Aggregation-Induced Emission (AIE) luminogens in biosensor, bioimaging, and biomedicine. The 2nd volume presents the applications of AIE materials in biomedicine, including the utilizations in biomedical polymers, organic nanoprobes, photosensitizer, AIEgens-based delivery systems, etc. It is an essential reference for materials scientists, physicists and biological chemists.

Aggregation-Induced Emission (AIE) is a novel photophysical phenomenon which offers a new platform for researchers to look into the light-emitting processes from luminogen aggregates, from which useful information on structure–property relationships may be collected and mechanistic insights may be gained. The discovery of the AIE effect opens a new avenue for the development of new luminogen materials in the aggregate or solid state. By enabling light emission in the practically useful solid state, AIE has the potential to expand significantly the technological applications of luminescent materials. Aggregation-Induced Emission: Fundamentals is the first book to explore the fundamental issues of AIE, including the design, synthesis, and photophysical behavior of AIE-active molecules and polymers. The control of the morphological structures of the aggregates of AIE-active materials, and the experimental investigation and theoretical understanding of the AIE mechanism, are also covered in this volume. Topics covered include: AIE in group 14 metalloles AIE in organic ion pairs Red light-emitting AIE materials Supramolecular structure and AIE AIE-active polymers Enhanced emission by restriction of molecular rotation Crystallization-induced emission enhancement Theoretical understanding of AIE phenomena This book is essential reading for scientists and engineers who are designing optoelectronic materials and biomedical sensors, and will also be of interest to academic researchers in materials science and physical and synthetic organic chemistry, as well as physicists and biological chemists.

Polyamic Acids and Polyimides surveys significant developments in basic research in the chemistry and physics of polyamic acids and polyimides over the last several years. Traditional and new topics are discussed, including catalytical imidization, chemical reactions at thermal treatment, quantum-chemical study of synthesis and structure, properties of isolated molecules, and supermolecular and crystalline structures. The book will be an excellent reference for researchers, practitioners, and graduate students working with polyimides and related heat-resistant polymers and materials.