Model Systems to Study the Mechanisms of Neural Development and Disease
Author | : Parthiv Haldipur |
Publisher | : Frontiers Media SA |
Total Pages | : 167 |
Release | : |
ISBN-10 | : 9782889767076 |
ISBN-13 | : 2889767078 |
Rating | : 4/5 (76 Downloads) |
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Author | : Parthiv Haldipur |
Publisher | : Frontiers Media SA |
Total Pages | : 167 |
Release | : |
ISBN-10 | : 9782889767076 |
ISBN-13 | : 2889767078 |
Rating | : 4/5 (76 Downloads) |
Author | : National Research Council |
Publisher | : National Academies Press |
Total Pages | : 610 |
Release | : 2000-11-13 |
ISBN-10 | : 9780309069885 |
ISBN-13 | : 0309069882 |
Rating | : 4/5 (85 Downloads) |
How we raise young children is one of today's most highly personalized and sharply politicized issues, in part because each of us can claim some level of "expertise." The debate has intensified as discoveries about our development-in the womb and in the first months and years-have reached the popular media. How can we use our burgeoning knowledge to assure the well-being of all young children, for their own sake as well as for the sake of our nation? Drawing from new findings, this book presents important conclusions about nature-versus-nurture, the impact of being born into a working family, the effect of politics on programs for children, the costs and benefits of intervention, and other issues. The committee issues a series of challenges to decision makers regarding the quality of child care, issues of racial and ethnic diversity, the integration of children's cognitive and emotional development, and more. Authoritative yet accessible, From Neurons to Neighborhoods presents the evidence about "brain wiring" and how kids learn to speak, think, and regulate their behavior. It examines the effect of the climate-family, child care, community-within which the child grows.
Author | : National Research Council |
Publisher | : National Academies Press |
Total Pages | : 348 |
Release | : 2000-12-21 |
ISBN-10 | : 9780309070867 |
ISBN-13 | : 0309070864 |
Rating | : 4/5 (67 Downloads) |
Scientific Frontiers in Developmental Toxicology and Risk Assessment reviews advances made during the last 10-15 years in fields such as developmental biology, molecular biology, and genetics. It describes a novel approach for how these advances might be used in combination with existing methodologies to further the understanding of mechanisms of developmental toxicity, to improve the assessment of chemicals for their ability to cause developmental toxicity, and to improve risk assessment for developmental defects. For example, based on the recent advances, even the smallest, simplest laboratory animals such as the fruit fly, roundworm, and zebrafish might be able to serve as developmental toxicological models for human biological systems. Use of such organisms might allow for rapid and inexpensive testing of large numbers of chemicals for their potential to cause developmental toxicity; presently, there are little or no developmental toxicity data available for the majority of natural and manufactured chemicals in use. This new approach to developmental toxicology and risk assessment will require simultaneous research on several fronts by experts from multiple scientific disciplines, including developmental toxicologists, developmental biologists, geneticists, epidemiologists, and biostatisticians.
Author | : Nicole Le Douarin |
Publisher | : Cambridge University Press |
Total Pages | : 494 |
Release | : 1999-11-28 |
ISBN-10 | : 0521620104 |
ISBN-13 | : 9780521620109 |
Rating | : 4/5 (04 Downloads) |
This 1999 edition of The Neural Crest contains comprehensive information about the neural crest, a structure unique to the vertebrate embryo, which has only a transient existence in early embryonic life. The ontogeny of the neural crest embodies the most important issues in developmental biology, as the neural crest is considered to have played a crucial role in evolution of the vertebrate phylum. Data that analyse neural crest ontogeny in murine and zebrafish embryos have been included in this revision. This revised edition also takes advantage of recent advances in our understanding of markers of neural crest cell subpopulations, and a full chapter is now devoted to cell lineage analysis. The major research breakthrough since the first edition has been the introduction of molecular biology to neural crest research, enabling an elucidation of many molecular mechanisms of neural crest development. This book is essential reading for students and researchers in developmental biology, cell biology, and neuroscience.
Author | : National Research Council |
Publisher | : National Academies Press |
Total Pages | : 223 |
Release | : 2003-08-22 |
ISBN-10 | : 9780309167857 |
ISBN-13 | : 030916785X |
Rating | : 4/5 (57 Downloads) |
Expanding on the National Research Council's Guide for the Care and Use of Laboratory Animals, this book deals specifically with mammals in neuroscience and behavioral research laboratories. It offers flexible guidelines for the care of these animals, and guidance on adapting these guidelines to various situations without hindering the research process. Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research offers a more in-depth treatment of concerns specific to these disciplines than any previous guide on animal care and use. It treats on such important subjects as: The important role that the researcher and veterinarian play in developing animal protocols. Methods for assessing and ensuring an animal's well-being. General animal-care elements as they apply to neuroscience and behavioral research, and common animal welfare challenges this research can pose. The use of professional judgment and careful interpretation of regulations and guidelines to develop performance standards ensuring animal well-being and high-quality research. Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research treats the development and evaluation of animal-use protocols as a decision-making process, not just a decision. To this end, it presents the most current, in-depth information about the best practices for animal care and use, as they pertain to the intricacies of neuroscience and behavioral research.
Author | : Daniel Laskowitz |
Publisher | : CRC Press |
Total Pages | : 388 |
Release | : 2016-04-21 |
ISBN-10 | : 9781498766579 |
ISBN-13 | : 1498766579 |
Rating | : 4/5 (79 Downloads) |
Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the developme
Author | : William M. Reichert |
Publisher | : CRC Press |
Total Pages | : 300 |
Release | : 2007-12-17 |
ISBN-10 | : 9781420009309 |
ISBN-13 | : 1420009303 |
Rating | : 4/5 (09 Downloads) |
Despite enormous advances made in the development of external effector prosthetics over the last quarter century, significant questions remain, especially those concerning signal degradation that occurs with chronically implanted neuroelectrodes. Offering contributions from pioneering researchers in neuroprosthetics and tissue repair, Indwel
Author | : Jan Pruszak |
Publisher | : Academic Press |
Total Pages | : 253 |
Release | : 2015-03-23 |
ISBN-10 | : 9780128011263 |
ISBN-13 | : 0128011262 |
Rating | : 4/5 (63 Downloads) |
Neural Surface Antigens: From Basic Biology towards Biomedical Applications focuses on the functionalrole of surface molecules in neural development, stem cell research, and translational biomedical paradigms.With an emphasis on human and rodent model systems, this reference covers fundamentals of neural stemcell biology and flow cytometric methodology. Addressing cell biologists as well as clinicians working in theneurosciences, the book was conceived by an international panel of experts to cover a vast array of particularsurface antigen families and subtypes. It provides insight into the basic biology and functional mechanisms ofneural cell surface signaling molecules influencing mammalian development, regeneration, and treatments. - Introduces early phase clinical trials of neural stem cells - Outlines characterization of surface molecule expression and methods for isolation which open unprecedented opportunities for functional study, quantitation & diagnostics - Highlights the role of stem cells in neural surface antigen and biomarker analysis and applications
Author | : Katherine Elliott |
Publisher | : John Wiley & Sons |
Total Pages | : 192 |
Release | : 2009-09-14 |
ISBN-10 | : 9780470718346 |
ISBN-13 | : 047071834X |
Rating | : 4/5 (46 Downloads) |
The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.
Author | : Georg F. Striedter |
Publisher | : Academic Press |
Total Pages | : 2064 |
Release | : 2016-11-23 |
ISBN-10 | : 9780128040966 |
ISBN-13 | : 0128040963 |
Rating | : 4/5 (66 Downloads) |
Evolution of Nervous Systems, Second Edition, Four Volume Set is a unique, major reference which offers the gold standard for those interested both in evolution and nervous systems. All biology only makes sense when seen in the light of evolution, and this is especially true for the nervous system. All animals have nervous systems that mediate their behaviors, many of them species specific, yet these nervous systems all evolved from the simple nervous system of a common ancestor. To understand these nervous systems, we need to know how they vary and how this variation emerged in evolution. In the first edition of this important reference work, over 100 distinguished neuroscientists assembled the current state-of-the-art knowledge on how nervous systems have evolved throughout the animal kingdom. This second edition remains rich in detail and broad in scope, outlining the changes in brain and nervous system organization that occurred from the first invertebrates and vertebrates, to present day fishes, reptiles, birds, mammals, and especially primates, including humans. The book also includes wholly new content, fully updating the chapters in the previous edition and offering brand new content on current developments in the field. Each of the volumes has been carefully restructured to offer expanded coverage of non-mammalian taxa, mammals, primates, and the human nervous system. The basic principles of brain evolution are discussed, as are mechanisms of change. The reader can select from chapters on highly specific topics or those that provide an overview of current thinking and approaches, making this an indispensable work for students and researchers alike. Presents a broad range of topics, ranging from genetic control of development in invertebrates, to human cognition, offering a one-stop resource for the evolution of nervous systems throughout the animal kingdom Incorporates the expertise of over 100 outstanding investigators who provide their conclusions in the context of the latest experimental results Presents areas of disagreement and consensus views that provide a holistic view of the subjects under discussion