This volume contains the proceedings of the 8th Workshop on Model-Oriented Design and Analysis. It offers leading and pioneering work on optimal experimental designs, both from a mathematical/statistical point of view and with regard to real applications. Scientists from all over the world have contributed to this volume. Primary topics are designs for nonlinear models and applications to experimental medicine.

This volume contains pioneering contributions to both the theory and practice of optimal experimental design. Topics include the optimality of designs in linear and nonlinear models, as well as designs for correlated observations and for sequential experimentation. There is an emphasis on applications to medicine, in particular, to the design of clinical trials. Scientists from Europe, the US, Asia, Australia and Africa contributed to this volume of papers from the 11th Workshop on Model Oriented Design and Analysis.

The volume contains the proceedings of the 7th Workshop on Model-Oriented Design and Analysis which has had the purpose of bringing together leading researchers in Eastern and Western Europe for an in-depth discussion of the optimal design of experiments. The papers are representative of the latest developments concerning non-linear models, computational algorithms and important applications, especially to medical statistics.

Provides timely applications, modifications, and extensions of experimental designs for a variety of disciplines Design and Analysis of Experiments, Volume 3: Special Designs and Applications continues building upon the philosophical foundations of experimental design by providing important, modern applications of experimental design to the many fields that utilize them. The book also presents optimal and efficient designs for practice and covers key topics in current statistical research. Featuring contributions from leading researchers and academics, the book demonstrates how the presented concepts are used across various fields from genetics and medicinal and pharmaceutical research to manufacturing, engineering, and national security. Each chapter includes an introduction followed by the historical background as well as in-depth procedures that aid in the construction and analysis of the discussed designs. Topical coverage includes: Genetic cross experiments, microarray experiments, and variety trials Clinical trials, group-sequential designs, and adaptive designs Fractional factorial and search, choice, and optimal designs for generalized linear models Computer experiments with applications to homeland security Robust parameter designs and split-plot type response surface designs Analysis of directional data experiments Throughout the book, illustrative and numerical examples utilize SAS®, JMP®, and R software programs to demonstrate the discussed techniques. Related data sets and software applications are available on the book's related FTP site. Design and Analysis of Experiments, Volume 3 is an ideal textbook for graduate courses in experimental design and also serves as a practical, hands-on reference for statisticians and researchers across a wide array of subject areas, including biological sciences, engineering, medicine, and business.

This book arises from the International Spring School "Advances and Challenges in Space-Time modelling of Natural Events," which took place March 2010. It details recent developments, new methods and applications in spatial statistics and related areas. This book arises from the International Spring School "Advances and Challenges in Space-Time modelling of Natural Events," which took place March 2010. It details recent developments, new methods and applications in spatial statistics and related areas.

Selected from the conference "S.Co.2009: Complex Data Modeling and Computationally Intensive Methods for Estimation and Prediction," these 20 papers cover the latest in statistical methods and computational techniques for complex and high dimensional datasets.

This handbook focuses on the enormous literature applying statistical methodology and modelling to environmental and ecological processes. The 21st century statistics community has become increasingly interdisciplinary, bringing a large collection of modern tools to all areas of application in environmental processes. In addition, the environmental community has substantially increased its scope of data collection including observational data, satellite-derived data, and computer model output. The resultant impact in this latter community has been substantial; no longer are simple regression and analysis of variance methods adequate. The contribution of this handbook is to assemble a state-of-the-art view of this interface. Features: An internationally regarded editorial team. A distinguished collection of contributors. A thoroughly contemporary treatment of a substantial interdisciplinary interface. Written to engage both statisticians as well as quantitative environmental researchers. 34 chapters covering methodology, ecological processes, environmental exposure, and statistical methods in climate science.

Assembling a collection of very prominent researchers in the field, the Handbook of Spatial Statistics presents a comprehensive treatment of both classical and state-of-the-art aspects of this maturing area. It takes a unified, integrated approach to the material, providing cross-references among chapters.The handbook begins with a historical intro

This volume is the English version of the second edition of the bilingual textbook by Rasch, Verdooren and Gowers (1999). A parallel version in German is available from the same publisher. This book is intended for students and experimental scientists in all disciplines and presumes only elementary statistical knowledge. This prerequisite knowledge is summarised briefly in appendix B. Knowledge of differential and integral calculus is not necessary for the understanding of the text. Matrix notation is explained in Appendix C. As well as the correction of errors, the present edition differs from the first by the introduction of some new sections, such as that on testing the equality of two proportions (Section 3.4.4), and the inclusion of sequential tests. All new material is accompanied by descriptions of the relevant SPSS and CADEMO procedures.

This book is a tribute to Professor Pedro Gil, who created the Department of Statistics, OR and TM at the University of Oviedo, and a former President of the Spanish Society of Statistics and OR (SEIO). In more than eighty original contributions, it illustrates the extent to which Mathematics can help manage uncertainty, a factor that is inherent to real life. Today it goes without saying that, in order to model experiments and systems and to analyze related outcomes and data, it is necessary to consider formal ideas and develop scientific approaches and techniques for dealing with uncertainty. Mathematics is crucial in this endeavor, as this book demonstrates. As Professor Pedro Gil highlighted twenty years ago, there are several well-known mathematical branches for this purpose, including Mathematics of chance (Probability and Statistics), Mathematics of communication (Information Theory), and Mathematics of imprecision (Fuzzy Sets Theory and others). These branches often intertwine, since different sources of uncertainty can coexist, and they are not exhaustive. While most of the papers presented here address the three aforementioned fields, some hail from other Mathematical disciplines such as Operations Research; others, in turn, put the spotlight on real-world studies and applications. The intended audience of this book is mainly statisticians, mathematicians and computer scientists, but practitioners in these areas will certainly also find the book a very interesting read.