Microdosimetry and Its Applications is an advanced textbook presenting the fundamental concepts and numerical aspects of the absorption of energy by matter exposed to ionizing radiation. It is the only comprehensive work on the subject that can be considered definitive. It provides a deeper understanding of the initial phase of the interaction of ionizing radiation with matter, especially biological matter, and its consequences.

Experimental microdosimetry deals with the measurement of charged particle energy deposition in tissue equivalent volumes, ranging in size from nanometres to micrometres. Microdosimetry is employed to improve our understanding of the relationship between radiation energy deposition, the resulting biological effects, and the appropriate quantities to be used in characterizing and quantifying radiation quality. Although many reviews and contributions to the field have been published over the past fifty years, this new book is the first to provide a single, up to date, and easily accessible account of experimental microdosimetry. This book is designed to be used in medical, radiation, and health physics courses and by Master’s and PhD students. In addition to serving as an introductory text to the field for graduate students, this book will also be of interest as a teaching and reference resource for graduate supervisors and established researchers. Drs. Lennart Lindborg and Anthony Waker have spent a life-time career in experimental microdosimetry research in academic, industrial and regulatory environments and have observed the development of the field from its early days as a recognized discipline; they bring to this book particular knowledge and experience in the design, construction, operation and use of tissue equivalent gas ionization counters and chambers.

Physics and Engineering of Radiation Detection presents an overview of the physics of radiation detection and its applications. It covers the origins and properties of different kinds of ionizing radiation, their detection and measurement, and the procedures used to protect people and the environment from their potentially harmful effects. The second edition is fully revised and provides the latest developments in detector technology and analyses software. Also, more material related to measurements in particle physics and a complete solutions manual have been added.

One of the aims of this book was to focus the attention of specialists to the diversity of the effects of the ionising radiation on biological and physical systems. Special emphasis has been placed on the exquisite complexities/differences introduced by high ionisation density versus low ionisation density irradiation in both biological and physical systems (Scholz – Chapter 1, Horowitz – Chapter 2, Olko – Chapter 3). As well we wanted to point out the need for novel experimental and theoretical approaches required to advance the important fields of micro and nanodosimetry. Important first steps have already been taken, for example, the accelerated application of semiconductor detectors in their various forms to microdosimetry and as well to practical, important applications in the radiation dosimetry of oncological procedures (Rosenfeld – Chapter 6). The vast number of applications of TLD to radiation dosimetry are not neglected; a special chapter is devoted to the application of TLDs to medical dosimetry applications (Mobit and Kron – Chapter 7) as well as a tutorial approach in an additional chapter to the cavity theories required to extrapolate dose from the detector medium to the tissue medium (Mobit and Sandison - Chapter 5). One of the major features of this book is the intensive, in depth, coverage of the theory and modelling of TL both from the solid state physics point of view (Chen – Chapter 4) and the microdosimetic point of view (Horowitz – Chapter 2 and Olko – Chapter 3). The many puzzling, quaint, quizzical features of TL science can now be understood in the framework of these advanced theoretical models, explained in straightforward, understandable terms.· Quantifies/unifies the effects of ionising radiation in both the biological and physical systems· Authoritative treatment of applications of semiconductor detectors and thermoluminescence dosemeters in medica l radiation dosimetry· Basic and advanced aspects of microdosimetry applied to both biological and physical systems· In-depth review of the effects of the density of ionising radiation in tsl and osl · Concise and elegant treatment of cavity theory in medical oncological dosimetry· Comprehensive review of this important interdisciplinary field including hundreds of ilustrations and references

This book is intended as a textbook that presents a modern approach to radiation dosimetry, covering the principles and applications of microdosimetry in radiation dosimetry, radiation protection, radiation biophysics and radiotherapy. It is designed to be used in medical and radiation physics courses and by Master and PhD students in medical radiation physics. Designed to be academic as well as practical, it is the first book of its kind suitable for both teaching and researching various radiation dosimetry topics.

This book describes hazards from radon progeny and other alpha-emitters that humans may inhale or ingest from their environment. In their analysis, the authors summarize in one document clinical and epidemiological evidence, the results of animal studies, research on alpha-particle damage at the cellular level, metabolic pathways for internal alpha-emitters, dosimetry and microdosimetry of radionuclides deposited in specific tissues, and the chemical toxicity of some low-specific-activity alpha-emitters. Techniques for estimating the risks to humans posed by radon and other internally deposited alpha-emitters are offered, along with a discussion of formulas, models, methods, and the level of uncertainty inherent in the risk estimates.

This newly revised and updated edition of Radiation Biophysics provides an in-depth description of the physics and chemistry of radiation and its effects on biological systems. Coverage begins with fundamental concepts of the physics of radiation and radioactivity, then progresses through the chemistry and biology of the interaction of radiation with living systems. The Second Edition of this highly praised text includes major revisions which reflect the rapid advances in the field. New material covers recent developments in the fields of carcinogenesis, DNA repair, molecular genetics, and the molecular biology of oncogenes and tumor suppressor genes. The book also includes extensive discussion of the practical impact of radiation on everyday life. - Covers the fundamentals of radiation physics in a manner that is understandable to students and professionals with a limited physics background - Includes problem sets and exercises to aid both teachers and students - Discusses radioactivity, internally deposited radionuclides, and dosimetry - Analyzes the risks for occupational and non-occupational workers exposed to radiation sources

This book is a guide to the use of Monte Carlo techniques in radiation transport. This topic is of great interest for medical physicists. Praised as a "gold standard" for accurate radiotherapy dose calculations, Monte Carlo has stimulated a high level of research activity that has produced thousands of papers within the past few years. The book is designed primarily to address the needs of an academically inclined medical physicist who wishes to learn the technique, as well as experienced users of standard Monte Carlo codes who wish to gain insight into the underlying mathematics of Monte Carlo algorithms. The book focuses on the fundamentals—giving full attention to and explaining the very basic concepts. It also includes advanced topics and covers recent advances such as transport of charged particles in magnetic fields and the grid-based solvers of the Boltzmann equation.

Frontiers in Neutron Capture Therapy contains current research results originally presented at the Eighth International Symposium on Neutron Capture Therapy for Cancer in La Jolla, CA. This comprehensive collection of peer-reviewed manuscripts is showcased in two volumes covering all aspects of the development of this multidisciplinary approach to cancer therapy. Volume I of this work includes clinical results and current progress in treatment planning, neutron sources and dosimetry, while Volume II presents the synthesis, pharmacology and tissue-targeting design of boron compounds, including work on preclinical dosimetry and radiobiology. Intended for researchers and clinicians involved with or interested in new modes of cancer therapy, this volume will also serve as a useful guideline for scientists, students, and practitioners in the field.