This book treats an important set of techniques that provide a mathematically rigorous and complete error analysis for computational results. It shows that interval analysis provides a powerful set of tools with direct applicability to important problems in scientific computing.

Mathematics of Computing -- Numerical Analysis.

At the core of many engineering problems is the solution of sets of equa tions and inequalities, and the optimization of cost functions. Unfortunately, except in special cases, such as when a set of equations is linear in its un knowns or when a convex cost function has to be minimized under convex constraints, the results obtained by conventional numerical methods are only local and cannot be guaranteed. This means, for example, that the actual global minimum of a cost function may not be reached, or that some global minimizers of this cost function may escape detection. By contrast, interval analysis makes it possible to obtain guaranteed approximations of the set of all the actual solutions of the problem being considered. This, together with the lack of books presenting interval techniques in such a way that they could become part of any engineering numerical tool kit, motivated the writing of this book. The adventure started in 1991 with the preparation by Luc Jaulin of his PhD thesis, under Eric Walter's supervision. It continued with their joint supervision of Olivier Didrit's and Michel Kieffer's PhD theses. More than two years ago, when we presented our book project to Springer, we naively thought that redaction would be a simple matter, given what had already been achieved . . .

Mathematics of Computing -- Numerical Analysis.

An update on the author's previous books, this introduction to interval analysis provides an introduction to INTLAB, a high-quality, comprehensive MATLAB toolbox for interval computations, making this the first interval analysis book that does with INTLAB what general numerical analysis texts do with MATLAB.

Interval-Censored Time-to-Event Data: Methods and Applications collects the most recent techniques, models, and computational tools for interval-censored time-to-event data. Top biostatisticians from academia, biopharmaceutical industries, and government agencies discuss how these advances are impacting clinical trials and biomedical research. Divided into three parts, the book begins with an overview of interval-censored data modeling, including nonparametric estimation, survival functions, regression analysis, multivariate data analysis, competing risks analysis, and other models for interval-censored data. The next part presents interval-censored methods for current status data, Bayesian semiparametric regression analysis of interval-censored data with monotone splines, Bayesian inferential models for interval-censored data, an estimator for identifying causal effect of treatment, and consistent variance estimation for interval-censored data. In the final part, the contributors use Monte Carlo simulation to assess biases in progression-free survival analysis as well as correct bias in interval-censored time-to-event applications. They also present adaptive decision making methods to optimize the rapid treatment of stroke, explore practical issues in using weighted logrank tests, and describe how to use two R packages. A practical guide for biomedical researchers, clinicians, biostatisticians, and graduate students in biostatistics, this volume covers the latest developments in the analysis and modeling of interval-censored time-to-event data. It shows how up-to-date statistical methods are used in biopharmaceutical and public health applications.

Employing a closed set-theoretic foundation for interval computations, Global Optimization Using Interval Analysis simplifies algorithm construction and increases generality of interval arithmetic. This Second Edition contains an up-to-date discussion of interval methods for solving systems of nonlinear equations and global optimization problems. It expands and improves various aspects of its forerunner and features significant new discussions, such as those on the use of consistency methods to enhance algorithm performance. Provided algorithms are guaranteed to find and bound all solutions to these problems despite bounded errors in data, in approximations, and from use of rounded arithmetic.

This brief presents a suite of computationally efficient methods for bounding trajectories of dynamical systems with multi-dimensional intervals, or ‘boxes’. It explains the importance of bounding trajectories for evaluating the robustness of systems in the face of parametric uncertainty, and for verification or control synthesis problems with respect to safety and reachability properties. The methods presented make use of: interval analysis; monotonicity theory; contraction theory; and data-driven techniques that sample trajectories. The methods are implemented in an accompanying open-source Toolbox for Interval Reachability Analysis. This brief provides a tutorial description of each method, focusing on the requirements and trade-offs relevant to the user, requiring only basic background on dynamical systems. The second part of the brief describes applications of interval reachability analysis. This makes the brief of interest to a wide range of academic researchers, graduate students, and practising engineers in the field of control and verification.

This book presents an innovative new approach to interval analysis. Modal Interval Analysis (MIA) is an attempt to go beyond the limitations of classic intervals in terms of their structural, algebraic and logical features. The starting point of MIA is quite simple: It consists in defining a modal interval that attaches a quantifier to a classical interval and in introducing the basic relation of inclusion between modal intervals through the inclusion of the sets of predicates they accept. This modal approach introduces interval extensions of the real continuous functions, identifies equivalences between logical formulas and interval inclusions, and provides the semantic theorems that justify these equivalences, along with guidelines for arriving at these inclusions. Applications of these equivalences in different areas illustrate the obtained results. The book also presents a new interval object: marks, which aspire to be a new form of numerical treatment of errors in measurements and computations.

A unified discussion of the formulation and analysis of special methods of mixed initial boundary-value problems. The focus is on the development of a new mathematical theory that explains why and how well spectral methods work. Included are interesting extensions of the classical numerical analysis.