Following an introduction to biogenic metal nanoparticles, this book presents how they can be biosynthesized using bacteria, fungi and yeast, as well as their potential applications in biomedicine. It is shown that the synthesis of nanoparticles using microbes is eco-friendly and results in reproducible metal nanoparticles of well-defined sizes, shapes and structures. This biotechnological approach based on the process of biomineralization exploits the effectiveness and flexibility of biological systems. Chapters include practical protocols for microbial synthesis of nanoparticles and microbial screening methods for isolating a specific nanoparticle producer as well as reviews on process optimization, industrial scale production, biomolecule-nanoparticle interactions, magnetosomes, silver nanoparticles and their numerous applications in medicine, and the application of gold nanoparticles in developing sensitive biosensors.

Bacterial pathogens have been becoming the main problem in hospital and community-acquired infections. It is hard to treat the strains that are resistant to antibiotics, due to the causing recurrent and untreatable infections. In recent years, the combination treatments and the novel technologies have been preferred to overcome the emergence of antibacterial resistance of pathogens. In this book, examples of pathogenesis by clinical cases, control by antibiotics and bioactive antimicrobials, control by novel technologies with the collection of up-to-date researches and reviews are presented. This book can be useful for researchers interested in antibacterials, bioactive compounds, and novel technologies.

This book introduces the principles and mechanisms of the biological synthesis of nanoparticles from microorganisms, including bacteria, fungi, viruses, algae, and protozoans. It presents optimization processes for synthesis of microbes-mediated nanoparticles. The book also reviews the industrial and agricultural applications of microbially-synthesized nanoparticles. It also presents the medical applications of green nanoparticles, such as treating multidrug-resistant pathogens and cancer treatment. Further, it examines the advantages and prospects for the synthesis of nanoparticles by microorganisms. Lastly, it also presents the utilization of microbial-synthesized nanoparticles in the bioremediation of heavy metals.

Nanotechnology has gained attention in all aspects of modern science, having vital applications in the food chain, storage, quality monitoring, processing, preservation, and packaging. The global population is increasing rapidly, therefore there is a requirement to produce food products in a more proficient, non-toxic, and sustainable way. Food scientists and microbiologists are interested in food safety and quality assurance to produce excellent-quality food free of food pathogens Nanotechnological Approaches in Food Microbiology provides a systematic introduction and comprehensive information about practical approaches and characteristic features related to the significant applications of nanotechnology in food microbiology, including, nano-starch films, nanoemulsions, biogenic nanoparticles, and nanocapsules. The book will explore details about metal nanoparticle synthesis, characterization, mathematical modeling, kinetic studies, and their antimicrobial approaches. Key Features: Includes comprehensive knowledge on metal nanoparticle synthesis, characterization, mathematical modeling, kinetic studies and their antimicrobial approaches Lays out concepts of essential oil nanoemulsion and their potential antimicrobial applications Deals with the latest development in nano-starch composite biofilms containing bioactive constituents to inhibit pathogenic microbes Explores the nanocapsules as potential antimicrobial agents in food. Provides information regarding new biogenic nano-antimicrobials developed for the food safety and quality assurance This book will educate readers on the aspects of nanotechnology in food safety and quality assurance. Nanoemulsions, nanohydrogels, metal nanoparticles, nano-starch films, nanocapsules and nano-antimicrobials are the emerging essentials of nanotechnology that are used to preserve the food at greater extent. This book should be of interest to a large and varied audience of researchers in academia, industry, food processing, preservation, packaging, microbiology and policy regulations.

Combined fields of Microbiology and Nanotechnology have been most successful in providing novel solutions for protecting the health of humans and environment. This book covers the implications of nano-strategies to combat bacterial pathogens, applications of nanotechniques in microbiology, and innovative advances in the area of medical microbiology. Contents are divided into three sections -- Nanoscience in controlling bacterial pathogens, Nanoscience in Microbiology, Medical Microbiology. This volume is going to provide timely information about the technological advances of Nanoscience in the domain of Microbiology, with a special emphasis on Pathobiology. The book is a useful read for students and researchers in microbiology, nanotechnology and medical microbiology.

Nanobiotechnology: Microbes and Plant Assisted Synthesis of Nanoparticles, Mechanisms and Applications covers in detail the green synthesis of nanostructures of tailor-made size, shape and physico-chemical and opto-electronic properties. The rationale behind the selection of bacteria, cyanobacteria, algae, fungi, virus and medicinal plants for the synthesis of biologically active exotic nanoparticles for biomedical applications is also part of this book. It also explores metal recovery, bioconversion, detoxification and removal of heavy metals using nanobiotechnology and discusses the potential of nanobiotechnology to address environmental pollution and toxicity. The book further covers the economic and commercial aspects of such green nanobiotechnology initiatives, its current status in intellectual property rights like patents filed so far globally, technology transfers, and market potential. This information enables one to decipher the scope of biogenic nanoparticles and its prospects. - Provides an overview on the general and applied aspects on nanotechnology - Gives the scope of exploring bacteria, fungi, algae, virus and medicinal plants for the synthesis of exotic nanoparticles - Furnishes a comprehensive report on the underlying molecular mechanisms behind the biosynthesis of nanoparticles - Outlines sustainable alternative strategies of bioremediation of heavy metals, metal recovery, detoxification and bioconversion using nanobiotechnology - Explores the promises of patenting, technology transfer and commercialization potential of biogenic nanoparticles

This book provides an account of the biogenic synthesis of nanomaterials by using different microorganisms. The chapters are focused on the biosynthesis of various metal and metal oxide nanosized materials by using bacteria, actinomycetes, fungi, and algae, including mechanisms of microbial synthesis. Other chapters summarize recent developments of microbial-based nanostructures for the management of food-borne pathogens, plant pathogenic fungi, as nutrients, and biomedical applications. Microorganisms are discussed not only as biofactories for the synthesis of nanomaterials but also as removal agents of toxic metals from the environment. Exposure sources and ecotoxicity of microbially synthesized nanoparticles are also discussed.

There has been emergence of multidrug resistance problem all over the world due to overuse or underuse of antibiotics. Most microbes including bacteria, fungi, protozoans and others have developed resistance to antibiotics, and therefore, this problem is now recognized to be of global concern. Ubiquitous occurrence of multidrug-resistant bacteria decreases effectiveness of current treatment, which results in thousands of deaths all over the world. Hence, investigations for new alternatives and novel strategies are urgently needed to address the problem of multidrug resistance. The antimicrobial potential of essential oils and metallic nanoparticles represent an effective solution for microbial resistance. Moreover, the use of essential oils in combination with metallic nanoparticles may exert synergistic antimicrobial effects and would be a novel approach. Essential oils (EOs) are volatile, natural, aromatic oily liquids that can be obtained from several parts of plants especially the aerial ones such as leaves and flowers. They are derived from complex metabolic pathways in order to protect plants from diverse pathogenic microorganisms. In fact, the bioactivity of EOs have been confirmed by several studies which have demonstrated their antibacterial, antiviral, anti-inflammatory, antifungal, antimutagenic, anticarcinogenic, and antioxidant properties. Nanotechnology is one of the most important and emerging technologies, which has brought about a technological revolution in the world. It has enormous applications in the field of medicine. Nanoparticles are very important tools in curing different diseases in general and microbial diseases in particular due to their significantly novel and improved chemical, physical and biological properties and high surface area-to-volume ratio. Among these, metal nanoparticles are known to play pivotal role in various biomedical applications. In this context, nanoparticles such as silver have shown their potential and could emerge as the new generation of antimicrobials. Silver nanoparticles have broad-spectrum biological activities and hence are used in many biomedical applications. The various biomedical applications of silver nanoparticles include treatment of wounds, burns, in water-disinfecting systems, in nanobased bone implantations, in dentistry for the development of dental materials and as antibacterial, antivirals, anti-protozoals, anti-arthropods and anticancerous agents. Apart from silver, noble metal nanoparticles like gold and platinum and other nanoparticles copper, oxides of different metals, etc. have been also the materials of choice for many scientists for their biological applications. The book will be of interest to chemists, microbiologists, biotechnologist, food technologists, nanotechnologists, pharmacologists, clinicians and those interested in nature cure. Students will find this book useful and reader friendly.

MICROBIAL INTERACTIONS AT NANOBIOTECHNOLOGY INTERFACES This book covers a wide range of topics including synthesis of nanomaterials with specific size, shape, and properties, structure-function relationships, tailoring the surface of nanomaterials for improving the properties, interaction of nanomaterials with proteins/microorganism/eukaryotic cells, and applications in different sectors. This book also provides a strong foundation for researchers who are interested to venture into developing functionalized nanomaterials for any biological applications in their research. Practical concepts such as modelling nanomaterials, and simulating the molecular interactions with biomolecules, transcriptomic or genomic approaches, advanced imaging techniques to investigate the functionalization of nanomaterials/interaction of nanomaterials with biomolecules and microorganisms are some of the chapters that offer significant benefits to the researchers.

Nanotechnology is the application of science to control matter at the molecular level. It has become one of the most promising applied technologies in all areas of science. Nanoparticles have multi-functional properties and have created very interesting applications in various fields such as medicine, nutrition, bioenergy, agriculture and the environment. But the biogenic syntheses of monodispersed nanoparticles with specific sizes and shapes have been a challenge in biomaterial science. Nanoparticles are of great interest due to their extremely small size and large surface-to-volume ratio, which lead to both chemical and physical differences in their properties (e.g., mechanical properties, biological and sterical properties, catalytic activity, thermal and electrical conductivity, optical absorption and melting point) compared to bulk of the same chemical composition. Recently, however, synthesizing metal nanoparticles using green technology via microorganisms, plants, viruses, and so on, has been extensively studied and has become recognized as a green and efficient way for further exploiting biological systems as convenient nanofactories. Thus the biological synthesis of nanoparticles is increasingly regarded as a rapid, ecofriendly, and easily scaled-up technology. Today researchers are developing new techniques and materials using nanotechnology that may be suitable for plants to boost their native functions. Recently, biological nanoparticles were found to be more pharmacologically active than physico-chemically synthesized nanoparticles. Various applications of biosynthesized nanoparticles have been discovered, especially in the field of biomedical research, such as applications to specific delivery of drugs, use for tumor detection, angiogenesis, genetic disease and genetic disorder diagnosis, photoimaging, and photothermal therapy. Further, iron oxide nanoparticles have been applied to cancer therapy, hyperthermia, drug delivery, tissue repair, cell labeling, targeting and immunoassays, detoxification of biological fluids, magnetic resonance imaging, and magnetically responsive drug delivery therapy. Nanoparticle synthesis for plant byproducts for biomedical applications has vast potential. This book offers researchers in plant science and biomedicine the latest research and opportunity to develop new tools for the synthesis of environmentally friendly and cost-effective nanoparticles for applications in biomedicine as well as other various fields.