"The clinically proven plan to banish your burnout"--Jacket.

In the development of many medical technologies the beginning is characterised by an emphasis on the basic scientific principles of the technology and the optimisa tion of the functional aspects of the technology. As a technology matures there is a tendency for the underlying principles to be forgotten as the dinical applications begin to develop and the focus moves to an understanding of the dinical applica tion. This maturity brings with it new challenges for those involved in the use of the technology. An acceptance of the methodology may lead to a scaling back of the ba sic training of staff into the fundamentals of the techniques and lead to a lack of questioning as to those issues which lead to the optimisation in dinical applications. This lack of basic training may ultimately lead to a stifling of research and develop ment of the technology as a whole as trained staff becomes a scarce commodity. Nudear medicine is no exception to this development cyde. As a medical special ty the discipline has matured. The basic imaging technology has become more reli able in everyday use requiring less input from scientific staff. Clinical procedures have become protocols which are often followed without due understanding of the basic principles underlying the imaging procedure. This is clearly demonstrated when new radiopharmaceuticals are introduced into the market place.

This book encompasses our current understanding of the ensemble approach to many-body physics, phase transitions and other thermal phenomena, as well as the quantum foundations of linear response theory, kinetic equations and stochastic processes. It is destined to be a standard text for graduate students, but it will also serve the specialist-researcher in this fascinating field; some more elementary topics have been included in order to make the book self-contained.The historical methods of J Willard Gibbs and Ludwig Boltzmann, applied to the quantum description rather than phase space, are featured. The tools for computations in the microcanonical, canonical and grand-canonical ensembles are carefully developed and then applied to a variety of classical and standard quantum situations. After the language of second quantization has been introduced, strongly interacting systems, such as quantum liquids, superfluids and superconductivity, are treated in detail. For the connoisseur, there is a section on diagrammatic methods and applications.In the second part dealing with non-equilibrium processes, the emphasis is on the quantum foundations of Markovian behaviour and irreversibility via the Pauli-Van Hove master equation. Justifiable linear response expressions and the quantum-Boltzmann approach are discussed and applied to various condensed matter problems. From this basis the Onsager-Casimir relations are derived, together with the mesoscopic master equation, the Langevin equation and the Fokker-Planck truncation procedure. Brownian motion and modern stochastic problems such as fluctuations in optical signals and radiation fields briefly make the round.

This cutting-edge reference clearly explains pharmaceutical transport phenomena, demonstrating applications ranging from drug or nutrient uptake into vesicle or cell suspensions, drug dissolution and absorption across biological membranes, whole body kinetics, and drug release from polymer reservoirs and matrices to heat and mass transport in freeze-drying and hygroscopicity. Focuses on practical applications of drug delivery from a physical and mechanistic perspective, highlighting biological systems. Written by more than 30 international authorities in the field, Transport Processes in Pharmaceutical Systems discusses the crucial relationship between the transport process and thermodynamic factors analyzes the dynamics of diffusion at liquid-liquid, liquid-solid, and liquid-cultured cell interfaces covers prodrug design for improving membrane transport addresses the effects of external stimuli in altering some natural and synthetic polymer matrices examines properties of hydrogels, including synthesis, swelling degree, swelling kinetics, permeability, biocompatibility, and biodegradability presents mass transfer of drugs and pharmacokinetics based on mass balance descriptions and more! Containing over 1000 references and more than 1100 equations, drawings, photographs, micrographs, and tables, Transport Processes in Pharmaceutical Systems is a must-read resource for research pharmacists, pharmaceutical scientists and chemists, chemical engineers, physical chemists, and upper-level undergraduate and graduate students in these disciplines.

Discover the unexpected ways friends influence our personalities, choices, emotions, and even physical health in this fun and compelling examination of friendship, based on the latest scientific research and ever-relatable anecdotes. Why is dinner with friends often more laughter filled and less fraught than a meal with family? Although some say it’s because we choose our friends, it’s also because we expect less of them than we do of relatives. While we’re busy scrutinizing our romantic relationships and family dramas, our friends are quietly but strongly influencing everything from the articles we read to our weight fluctuations, from our sex lives to our overall happiness levels. Evolutionary psychologists have long theorized that friendship has roots in our early dependence on others for survival. These days, we still cherish friends but tend to undervalue their role in our lives. However, the skills one needs to make good friends are among the very skills that lead to success in life, and scientific research has recently exploded with insights about the meaningful and enduring ways friendships influence us. With people marrying later—and often not at all—and more families having just one child, these relationships may be gaining in importance. The evidence even suggests that at times friends have a greater hand in our development and well-being than do our romantic partners and relatives. Friends see each other through the process of growing up, shape each other’s interests and outlooks, and, painful though it may be, expose each other’s rough edges. Childhood and adolescence, in particular, are marked by the need to create distance between oneself and one’s parents while forging a unique identity within a group of peers, but friends continue to influence us, in ways big and small, straight through old age. Perpetually busy parents who turn to friends—for intellectual stimulation, emotional support, and a good dose of merriment—find a perfect outlet to relieve the pressures of raising children. In the office setting, talking to a friend for just a few minutes can temporarily boost one’s memory. While we romanticize the idea of the lone genius, friendship often spurs creativity in the arts and sciences. And in recent studies, having close friends was found to reduce a person’s risk of death from breast cancer and coronary disease, while having a spouse was not. Friendfluence surveys online-only pals, friend breakups, the power of social networks, envy, peer pressure, the dark side of amicable ties, and many other varieties of friendship. Told with warmth, scientific rigor, and a dash of humor, Friendfluence not only illuminates and interprets the science but draws on clinical psychology and philosophy to help readers evaluate and navigate their own important friendships.

In response to a request from the U.S. Army, a committee convened by the National Research Council (NRC) conducted the first in a sequence of studies evaluating the combined health effects of low-level exposure to two chemicals Army personnel are likely to be exposed to in firing tank weapons. The Army sought information on whether the two chemicals, hydrogen cyanide and carbon monoxide, result in similar health impacts and should be assessed together when establishing exposure limits. Based on a review of the scientific literature, the report finds that the biochemical health impacts of the chemicals are similar and that the Army's proposed approach to setting exposure limits is appropriate. Because previous research has focused on high exposures, this initial NRC report recommends that futher neurological studies at low concentrations of exposure to the chemicals be conducted.

Resilience is a crucial ingredient–perhaps the crucial ingredient–to a happy, healthy life. More than anything else, it's what determines how high we rise above what threatens to wear us down, from battling an illness, to bolstering a marriage, to carrying on after a national crisis. Everyone needs resilience, and now two expert psychologists share seven proven techniques for enhancing our capacity to weather even the cruelest setbacks. The science in The Resilience Factor takes an extraordinary leap from the research introduced in the bestselling Learned Optimism a decade ago. Just as hundreds of thousands of people were transformed by "flexible optimism," readers of this book will flourish, thanks to their enhanced ability to overcome obstacles of any kind. Karen Reivich and Andrew Shatté are seasoned resilience coaches and, through practical methods and vivid anecdotes, they prove that resilience is not just an ability that we're born with and need to survive, but a skill that anyone can learn and improve in order to thrive. Readers will first complete the Resilience Questionnaire to determine their own innate levels of resilience. Then, the system at the heart of The Resilience Factor will teach them to: • Cast off harsh self-criticisms and negative self-images • Navigate through the fallout of any kind of crisis • Cope with grief and anxiety • Overcome obstacles in relationships, parenting, or on the job • Achieve greater physical health • Bolster optimism, take chances, and embrace life In light of the unprecedented challenges we've recently faced, there’s never been a greater need to boost our resilience. Without resorting to feel-good pap or quick-fix clichés, The Resilience Factor is self-help at its best, destined to become a classic in the genre.

A comprehensive guide to the current theories and methodologies intrinsic to fixed-income securities Written by well-known experts from a cross section of academia and finance, Handbook of Fixed-Income Securities features a compilation of the most up-to-date fixed-income securities techniques and methods. The book presents crucial topics of fixed income in an accessible and logical format. Emphasizing empirical research and real-life applications, the book explores a wide range of topics from the risk and return of fixed-income investments, to the impact of monetary policy on interest rates, to the post-crisis new regulatory landscape. Well organized to cover critical topics in fixed income, Handbook of Fixed-Income Securities is divided into eight main sections that feature: • An introduction to fixed-income markets such as Treasury bonds, inflation-protected securities, money markets, mortgage-backed securities, and the basic analytics that characterize them • Monetary policy and fixed-income markets, which highlight the recent empirical evidence on the central banks’ influence on interest rates, including the recent quantitative easing experiments • Interest rate risk measurement and management with a special focus on the most recent techniques and methodologies for asset-liability management under regulatory constraints • The predictability of bond returns with a critical discussion of the empirical evidence on time-varying bond risk premia, both in the United States and abroad, and their sources, such as liquidity and volatility • Advanced topics, with a focus on the most recent research on term structure models and econometrics, the dynamics of bond illiquidity, and the puzzling dynamics of stocks and bonds • Derivatives markets, including a detailed discussion of the new regulatory landscape after the financial crisis and an introduction to no-arbitrage derivatives pricing • Further topics on derivatives pricing that cover modern valuation techniques, such as Monte Carlo simulations, volatility surfaces, and no-arbitrage pricing with regulatory constraints • Corporate and sovereign bonds with a detailed discussion of the tools required to analyze default risk, the relevant empirical evidence, and a special focus on the recent sovereign crises A complete reference for practitioners in the fields of finance, business, applied statistics, econometrics, and engineering, Handbook of Fixed-Income Securities is also a useful supplementary textbook for graduate and MBA-level courses on fixed-income securities, risk management, volatility, bonds, derivatives, and financial markets. Pietro Veronesi, PhD, is Roman Family Professor of Finance at the University of Chicago Booth School of Business, where he teaches Masters and PhD-level courses in fixed income, risk management, and asset pricing. Published in leading academic journals and honored by numerous awards, his research focuses on stock and bond valuation, return predictability, bubbles and crashes, and the relation between asset prices and government policies.

The thermochemistry of alloys has interested generations of scientists and the subject was treated in classical textbooks long ago, e.g. by Hume-Rothery, by Wagner, and by Kubaschewski and Alcock. Nevertheless, the appearance of new materials and the desire to improve traditional materials and metallurgical processes has kept up demand for more information on the thermodynamics of these systems. The advent of computing power has created new opportunities to tie various aspects and properties together, such as phase diagrams and thermodynamic functions, that are in principle thermodynamically inter related but were too cumbersome to work out before. The computer has also been a powerful tool in buUding and testing models that help to explain the underlying causes of non-ideal behavior. At the same time, these calculations have pinpointed areas, where additional and more accurate data are needed. In the laboratory, new methods, improved materials, and sophistica ted instrumentation have gradually changed the way in which experiments are done. Within the time span of perhaps thirty years, the development went from jotting down individual readings of data points to strip chart recording to automatic digital data acquisition. Scholars and students active in the field of "Thermochemistry of Alloys" convened for a NATO Advanced Study Institute at Kiel in August 1987 to discuss these developments. This book collects most of the lectures and seminar papers given at the Institute.

This study focuses on statics' original simplicity as an exercise in logic, without resort to extensive mathematical detail. Discussions of significant historical discoveries offer an enjoyable, useful view of the field. 1982 edition.