Providing the first glimpse of how associative memories are actually established in our brains, this book describes a research strategy for unravelling the mystery of memory and learning. The results of this experimental quest are described at several levels of biological complexity including animal behavior, neural systems, cellular and membrane physiology, and molecular regulation. The amply illustrated text is carefully structured to distinguish between observations and hypotheses, between attractive possibilities and empirical demonstrations. Dr Alkon progresses step-by-step through a series of experimental tests of intuitive conjectures on the nature of learning and memory. The book guides the reader through a scientific detective story that sheds new light on how we learn and how we remember.

The brain ... There is no other part of the human anatomy that is so intriguing. How does it develop and function and why does it sometimes, tragically, degenerate? The answers are complex. In Discovering the Brain, science writer Sandra Ackerman cuts through the complexity to bring this vital topic to the public. The 1990s were declared the "Decade of the Brain" by former President Bush, and the neuroscience community responded with a host of new investigations and conferences. Discovering the Brain is based on the Institute of Medicine conference, Decade of the Brain: Frontiers in Neuroscience and Brain Research. Discovering the Brain is a "field guide" to the brainâ€"an easy-to-read discussion of the brain's physical structure and where functions such as language and music appreciation lie. Ackerman examines: How electrical and chemical signals are conveyed in the brain. The mechanisms by which we see, hear, think, and pay attentionâ€"and how a "gut feeling" actually originates in the brain. Learning and memory retention, including parallels to computer memory and what they might tell us about our own mental capacity. Development of the brain throughout the life span, with a look at the aging brain. Ackerman provides an enlightening chapter on the connection between the brain's physical condition and various mental disorders and notes what progress can realistically be made toward the prevention and treatment of stroke and other ailments. Finally, she explores the potential for major advances during the "Decade of the Brain," with a look at medical imaging techniquesâ€"what various technologies can and cannot tell usâ€"and how the public and private sectors can contribute to continued advances in neuroscience. This highly readable volume will provide the public and policymakersâ€"and many scientists as wellâ€"with a helpful guide to understanding the many discoveries that are sure to be announced throughout the "Decade of the Brain."

This study offers interpretations of theories of memory and the body from Descartes to Coleridge.

There was some agreement about what memory traces were not, but little about what actually did characterize the memory trace. Yet models and theories of memory at the time could not help making implicit and often unrecognized assumptions about the memory trace. Originally published in 1982, this title aimed to strengthen the meagre base on which memory theories rested at the time. It challenges old assumptions and introduces new concepts, foremost the notion of singularity, as they become necessary to understand traces adequately. Some research data of the past was found in need of reinterpretation. The result is a new theory of the memory trace.

This book focuses on associative memory cells and their working principles, which can be applied to associative memories and memory-relevant cognitions. Providing comprehensive diagrams, it presents the author's personal perspectives on pathology and therapeutic strategies for memory deficits in patients suffering from neurological diseases and psychiatric disorders. Associative learning is a common approach to acquire multiple associated signals, including knowledge, experiences and skills from natural environments or social interaction. The identification of the cellular and molecular mechanisms underlying associative memory is important in furthering our understanding of the principles of memory formation and memory-relevant behaviors as well as in developing therapeutic strategies that enhance memory capacity in healthy individuals and improve memory deficit in patients suffering from neurological disease and psychiatric disorders. Although a series of hypotheses about neural substrates for associative memory has been proposed, numerous questions still need to be addressed, especially the basic units and their working principle in engrams and circuits specific for various memory patterns. This book summarizes the developments concerning associative memory cells reported in current and past literature, providing a valuable overview of the field for neuroscientists, psychologists and students.

Provides a thematically integrated analysis and discussion of neuroethical questions about memory capacity, content, and interventions.

This Classic Edition of the best-selling textbook offers an in-depth overview of approaches to the study of memory. With empirical research from both the real world and the neuropsychological clinic, the book explains the fundamental workings of human memory in a clear and accessible style. This edition contains a new introduction and concluding chapter in which the author reflects on how the book is organized, and also on how the field of memory has developed since it was first published. Essentials of Human Memory evolved from a belief that, although the amount we know about memory has increased enormously in recent years, it is still possible to explain it in a way that would be fully understood by the general reader. After a broad overview of approaches to the study of memory, short-term and working memory are discussed, followed by learning, the role of organizing in remembering and factors influencing forgetting, including emotional variables and claims for the role of repression in what has become known as the false memory syndrome. The way in which knowledge of the world is stored is discussed next, followed by an account of the processes underlying retrieval, and their application to the practical issues of eyewitness testimony. The breakdown of memory in the amnesic syndrome is discussed next, followed by discussion of the way in which memory develops in children, and declines in the elderly. After a section concerned with mnemonic techniques and memory improvement, the book ends with an overview of recent developments in the field of human memory. Written by the leading expert in human memory, recently awarded the British Psychological Society Research Board Lifetime Achievement Award, Essentials of Human Memory will be of interest to students of Cognitive Psychology, Neuropsychology, and anyone with an interest in the workings of memory.

This selection of reviews gives an up-to-date picture of memory research. Great progress has been made in identifying the memory trace at the molecular and cellular level and individual reviews address the major mechanisms by which changes in synaptic strength can persist. Exciting research at the systems level is also reviewed including the growing importance of changes in inhibitory interneurons and how they play a role in memory formation. Finally, reviews present cognitive and neurobiological models of human memory that explain, characterize and organize the act of memory within a coherent framework. - Provides an unique overview that covers all perspectives and methodological approaches to memory - Broad coverage of memory research from molecular to human studies in one source - Up-to-date reviews give the latest important ideas on memory formation

A comprehensive, multidisciplinary review, Neural Plasticity and Memory: From Genes to Brain Imaging provides an in-depth, up-to-date analysis of the study of the neurobiology of memory. Leading specialists share their scientific experience in the field, covering a wide range of topics where molecular, genetic, behavioral, and brain imaging techniq