The purpose of this volume is to present and discuss the many rich properties of the dynamical systems that appear in life science and medicine. It provides a fascinating survey of the theory of dynamical systems in biology and medicine. Each chapter will serve to introduce students and scholars to the state-of-the-art in an exciting area, to present new results, and to inspire future contributions to mathematical modeling in life science and medicine.

The aim of this book is to introduce the subject of mathematical modeling in the life sciences. It is intended for students of mathematics, the physical sciences, and engineering who are curious about biology. Additionally, it will be useful to students of the life sciences and medicine who are unsatisfied with mere description and who seek an understanding of biological mechanism and dynamics through the use of mathematics. The book will be particularly useful to premedical students, because it will introduce them not only to a collection of mathematical methods but also to an assortment of phenomena involving genetics, epidemics, and the physiology of the heart, lung, and kidney. Because of its introductory character, mathematical prerequisites are kept to a minimum; they involve only what is usually covered in the first semester of a calculus sequence. The authors have drawn on their extensive experience as modelers to select examples which are simple enough to be understood at this elementary level and yet realistic enough to capture the essence of significant biological phenomena drawn from the areas of population dynamics and physiology. Because the models presented are realistic, the book can serve not only as an introduction to mathematical methods but also as a mathematical introduction to the biological material itself. For the student, who enjoys mathematics, such an introduction will be far more stimulating and satisfying than the purely descriptive approach that is traditional in the biological sciences.

The result of lectures given by the authors at New York University, the University of Utah, and Michigan State University, the material is written for students who have had only one term of calculus, but it contains material that can be used in modeling courses in applied mathematics at all levels through early graduate courses. Numerous exercises are given as well as solutions to selected exercises, so as to lead readers to discover interesting extensions of that material. Throughout, illustrations depict physiological processes, population biology phenomena, corresponding models, and the results of computer simulations. Topics covered range from population phenomena to demographics, genetics, epidemics and dispersal; in physiological processes, including the circulation, gas exchange in the lungs, control of cell volume, the renal counter-current multiplier mechanism, and muscle mechanics; to mechanisms of neural control. Each chapter is graded in difficulty, so a reading of the first parts of each provides an elementary introduction to the processes and their models.

An accessible undergraduate textbook on the essential math concepts used in the life sciences The life sciences deal with a vast array of problems at different spatial, temporal, and organizational scales. The mathematics necessary to describe, model, and analyze these problems is similarly diverse, incorporating quantitative techniques that are rarely taught in standard undergraduate courses. This textbook provides an accessible introduction to these critical mathematical concepts, linking them to biological observation and theory while also presenting the computational tools needed to address problems not readily investigated using mathematics alone. Proven in the classroom and requiring only a background in high school math, Mathematics for the Life Sciences doesn't just focus on calculus as do most other textbooks on the subject. It covers deterministic methods and those that incorporate uncertainty, problems in discrete and continuous time, probability, graphing and data analysis, matrix modeling, difference equations, differential equations, and much more. The book uses MATLAB throughout, explaining how to use it, write code, and connect models to data in examples chosen from across the life sciences. Provides undergraduate life science students with a succinct overview of major mathematical concepts that are essential for modern biology Covers all the major quantitative concepts that national reports have identified as the ideal components of an entry-level course for life science students Provides good background for the MCAT, which now includes data-based and statistical reasoning Explicitly links data and math modeling Includes end-of-chapter homework problems, end-of-unit student projects, and select answers to homework problems Uses MATLAB throughout, and MATLAB m-files with an R supplement are available online Prepares students to read with comprehension the growing quantitative literature across the life sciences A solutions manual for professors and an illustration package is available

A few decades ago mathematics played a modest role in life sciences. Today, however, a great variety of mathematical methods is applied in biology and medicine. Practically every mathematical procedure that is useful in physics, chemistry, engineering, and economics has also found an important application in the life sciences. The past and present training of life scientists does by no means reflect this development. However, the impact ofthe fast growing number of applications of mathematical methods makes it indispensable that students in the life sciences are offered a basic training in mathematics, both on the undergraduate and the graduate level. This book is primarily designed as a textbook for an introductory course. Life scientists may also use it as a reference to find mathematical methods suitable to their research problems. Moreover, the book should be appropriate for self-teaching. It will also be a guide for teachers. Numerous references are included to assist the reader in his search for the pertinent literature.

This book develops the mathematical tools essential for students in the life sciences to describe interacting systems and predict their behavior. From predator-prey populations in an ecosystem, to hormone regulation within the body, the natural world abounds in dynamical systems that affect us profoundly. Complex feedback relations and counter-intuitive responses are common in nature; this book develops the quantitative skills needed to explore these interactions. Differential equations are the natural mathematical tool for quantifying change, and are the driving force throughout this book. The use of Euler’s method makes nonlinear examples tractable and accessible to a broad spectrum of early-stage undergraduates, thus providing a practical alternative to the procedural approach of a traditional Calculus curriculum. Tools are developed within numerous, relevant examples, with an emphasis on the construction, evaluation, and interpretation of mathematical models throughout. Encountering these concepts in context, students learn not only quantitative techniques, but how to bridge between biological and mathematical ways of thinking. Examples range broadly, exploring the dynamics of neurons and the immune system, through to population dynamics and the Google PageRank algorithm. Each scenario relies only on an interest in the natural world; no biological expertise is assumed of student or instructor. Building on a single prerequisite of Precalculus, the book suits a two-quarter sequence for first or second year undergraduates, and meets the mathematical requirements of medical school entry. The later material provides opportunities for more advanced students in both mathematics and life sciences to revisit theoretical knowledge in a rich, real-world framework. In all cases, the focus is clear: how does the math help us understand the science?

Freshman and sophomore life sciences students respond well to the modeling approach to calculus, difference equations, and differential equations presented in this book. Examples of population dynamics, pharmacokinetics, and biologically relevant physical processes are introduced in Chapter 1, and these and other life sciences topics are developed throughout the text. The students should have studied algebra, geometry, and trigonometry, but may be life sciences students because they have not enjoyed their previous mathematics courses.

This is the only book that teaches all aspects of modern mathematical modeling and that is specifically designed to introduce undergraduate students to problem solving in the context of biology. Included is an integrated package of theoretical modeling and analysis tools, computational modeling techniques, and parameter estimation and model validation methods, with a focus on integrating analytical and computational tools in the modeling of biological processes. Divided into three parts, it covers basic analytical modeling techniques; introduces computational tools used in the modeling of biological problems; and includes various problems from epidemiology, ecology, and physiology. All chapters include realistic biological examples, including many exercises related to biological questions. In addition, 25 open-ended research projects are provided, suitable for students. An accompanying Web site contains solutions and a tutorial for the implementation of the computational modeling techniques. Calculations can be done in modern computing languages such as Maple, Mathematica, and MATLAB?.

This book covers applications of fractional calculus used for medical and health science. It offers a collection of research articles built into chapters on classical and modern dynamical systems formulated by fractional differential equations describing human diseases and how to control them. The mathematical results included in the book will be helpful to mathematicians and doctors by enabling them to explain real-life problems accurately. The book will also offer case studies of real-life situations with an emphasis on describing the mathematical results and showing how to apply the results to medical and health science, and at the same time highlighting modeling strategies. The book will be useful to graduate level students, educators and researchers interested in mathematics and medical science.

The best laboratory math text on the market for almost 20 years, this title covers both the general principles of mathematics and specific equations, formulas, and calculations used for laboratory testing. It provides simple, easily understood explanations of calculations commonly used in clinical and biological laboratories. Contains more than 1000 practice problems.