This book deals with the prediction of possible future scenarios concerning the COVID-19 pandemic. Based on the well-known SIR model by Kermack and McKendrick a compartment model is established. This model comprises its own assumptions, transition rates and transmission dynamics, as well as a corresponding system of ordinary differential equations. Making use of numerical methods and a nonstandard-finite-difference scheme, two submodels are implemented in Matlab in order to make parameter estimations and compare different scenarios with each other.

The book is a comprehensive, self-contained introduction to the mathematical modeling and analysis of disease transmission models. It includes (i) an introduction to the main concepts of compartmental models including models with heterogeneous mixing of individuals and models for vector-transmitted diseases, (ii) a detailed analysis of models for important specific diseases, including tuberculosis, HIV/AIDS, influenza, Ebola virus disease, malaria, dengue fever and the Zika virus, (iii) an introduction to more advanced mathematical topics, including age structure, spatial structure, and mobility, and (iv) some challenges and opportunities for the future. There are exercises of varying degrees of difficulty, and projects leading to new research directions. For the benefit of public health professionals whose contact with mathematics may not be recent, there is an appendix covering the necessary mathematical background. There are indications which sections require a strong mathematical background so that the book can be useful for both mathematical modelers and public health professionals.

The book is a comprehensive, self-contained introduction to the mathematical modeling and analysis of infectious diseases. It includes model building, fitting to data, local and global analysis techniques. Various types of deterministic dynamical models are considered: ordinary differential equation models, delay-differential equation models, difference equation models, age-structured PDE models and diffusion models. It includes various techniques for the computation of the basic reproduction number as well as approaches to the epidemiological interpretation of the reproduction number. MATLAB code is included to facilitate the data fitting and the simulation with age-structured models.

Infectious diseases are leading threats and are of highest risk to the human population globally. Over the last two years, we saw the transmission of Covid-19. Millions of people died or were forced to live with a disability. Mathematical models are effective tools that enable analysis of relevant information, simulate the related process and evaluate beneficial results. They can help to make rational decisions to lead toward a healthy society. Formulation of mathematical models for a pollution-free environment is also very important for society. To determine the system which can be modelled, we need to formulate the basic context of the model underlying some necessary assumptions. This describes our beliefs in terms of the mathematical language of how the world functions. This book addresses issues during the Covid phase and post-Covid phase. It analyzes transmission, impact of coinfections, and vaccination as a control or to decrease the intensity of infection. It also talks about the violence and unemployment problems occurring during the post-Covid period. This book will help societal stakeholders to resume normality slowly and steadily.

Given the widespread interest in macroscopic phenomena in liquid crystals, stemming from their applications in displays and devices. The need has arisen for a rigorous yet accessible text suitable for graduate students, whatever their scientific background. This book satisfies that need. The approach taken in this text, is to introduce the basic continuum theory for nematic liquid crystals in equilibria, then it proceeds to simple application of this theory- in particular, there is a discussion of electrical and magnetic field effects which give rise to Freedericksz transitions, which are important in devices. This is followed by an account of dynamic theory and elementary viscometry of nemantics Discussions of backflow and flow-induced instabilities are also included. Smetic theory is also briefly introduced and summarised with some examples of equilibrium solutions as well as those with dynamic effects. A number of mathematical techniques, such as Cartesian tensors and some variational calculus, are presented in the appendices.

This second edition of Nonstandard Finite Difference Models of Differential Equations provides an update on the progress made in both the theory and application of the NSFD methodology during the past two and a half decades. In addition to discussing details related to the determination of the denominator functions and the nonlocal discrete representations of functions of dependent variables, we include many examples illustrating just how this should be done.Of real value to the reader is the inclusion of a chapter listing many exact difference schemes, and a chapter giving NSFD schemes from the research literature. The book emphasizes the critical roles played by the 'principle of dynamic consistency' and the use of sub-equations for the construction of valid NSFD discretizations of differential equations.

This book provides a clear summary of the work of the author on the construction of nonstandard finite difference schemes for the numerical integration of differential equations. The major thrust of the book is to show that discrete models of differential equations exist such that the elementary types of numerical instabilities do not occur. A consequence of this result is that in general bigger step-sizes can often be used in actual calculations and/or finite difference schemes can be constructed that are conditionally stable in many instances whereas in using standard techniques no such schemes exist. The theoretical basis of this work is centered on the concepts of ?exact? and ?best? finite difference schemes. In addition, a set of rules is given for the discrete modeling of derivatives and nonlinear expressions that occur in differential equations. These rules often lead to a unique nonstandard finite difference model for a given differential equation.

This text provides essential modeling skills and methodology for the study of infectious diseases through a one-semester modeling course or directed individual studies. The book includes mathematical descriptions of epidemiological concepts, and uses classic epidemic models to introduce different mathematical methods in model analysis. Matlab codes are also included for numerical implementations. It is primarily written for upper undergraduate and beginning graduate students in mathematical sciences who have an interest in mathematical modeling of infectious diseases. Although written in a rigorous mathematical manner, the style is not unfriendly to non-mathematicians.

This monograph concisely but thoroughly introduces the reader to the field of mathematical immunology. The book covers first basic principles of formulating a mathematical model, and an outline on data-driven parameter estimation and model selection. The authors then introduce the modeling of experimental and human infections and provide the reader with helpful exercises. The target audience primarily comprises researchers and graduate students in the field of mathematical biology who wish to be concisely introduced into mathematical immunology.

The main purpose of this book is to provide a concise introduction to the methods and philosophy of constructing nonstandard finite difference schemes and illustrate how such techniques can be applied to several important problems. Chapter I gives an overview of the subject and summarizes previous work. Chapters 2 and 3 consider in detail the construction and numerical implementation of schemes for physical problems involving convection-diffusion-reaction equations, that arise in groundwater pollution and scattering of electromagnetic waves using Maxwell's equations. Chapter 4 examines certain mathematical issues related to the nonstandard discretization of competitive and cooperative models for ecology. The application chapters illustrate well the power of nonstandard methods. In particular, for the same accuracy as obtained by standard techniques, larger step sizes can be used. This volume will satisfy the needs of scientists, engineers, and mathematicians who wish to know how to construct nonstandard schemes and see how these are applied to obtain numerical solutions of the differential equations which arise in the study of nonlinear dynamical systems modeling important physical phenomena.