Automatic detection and segmentation of anatomical structures in medical images are prerequisites to subsequent image measurements and disease quantification, and therefore have multiple clinical applications. This book presents an efficient object detection and segmentation framework, called Marginal Space Learning, which runs at a sub-second speed on a current desktop computer, faster than the state-of-the-art. Trained with a sufficient number of data sets, Marginal Space Learning is also robust under imaging artifacts, noise and anatomical variations. The book showcases 35 clinical applications of Marginal Space Learning and its extensions to detecting and segmenting various anatomical structures, such as the heart, liver, lymph nodes and prostate in major medical imaging modalities (CT, MRI, X-Ray and Ultrasound), demonstrating its efficiency and robustness.

This book describes the technical problems and solutions for automatically recognizing and parsing a medical image into multiple objects, structures, or anatomies. It gives all the key methods, including state-of- the-art approaches based on machine learning, for recognizing or detecting, parsing or segmenting, a cohort of anatomical structures from a medical image. Written by top experts in Medical Imaging, this book is ideal for university researchers and industry practitioners in medical imaging who want a complete reference on key methods, algorithms and applications in medical image recognition, segmentation and parsing of multiple objects. Learn: - Research challenges and problems in medical image recognition, segmentation and parsing of multiple objects - Methods and theories for medical image recognition, segmentation and parsing of multiple objects - Efficient and effective machine learning solutions based on big datasets - Selected applications of medical image parsing using proven algorithms - Provides a comprehensive overview of state-of-the-art research on medical image recognition, segmentation, and parsing of multiple objects - Presents efficient and effective approaches based on machine learning paradigms to leverage the anatomical context in the medical images, best exemplified by large datasets - Includes algorithms for recognizing and parsing of known anatomies for practical applications

Deep Learning for Medical Image Analysis, Second Edition is a great learning resource for academic and industry researchers and graduate students taking courses on machine learning and deep learning for computer vision and medical image computing and analysis. Deep learning provides exciting solutions for medical image analysis problems and is a key method for future applications. This book gives a clear understanding of the principles and methods of neural network and deep learning concepts, showing how the algorithms that integrate deep learning as a core component are applied to medical image detection, segmentation, registration, and computer-aided analysis.· Covers common research problems in medical image analysis and their challenges · Describes the latest deep learning methods and the theories behind approaches for medical image analysis · Teaches how algorithms are applied to a broad range of application areas including cardiac, neural and functional, colonoscopy, OCTA applications and model assessment · Includes a Foreword written by Nicholas Ayache

Medical Image Analysis presents practical knowledge on medical image computing and analysis as written by top educators and experts. This text is a modern, practical, self-contained reference that conveys a mix of fundamental methodological concepts within different medical domains. Sections cover core representations and properties of digital images and image enhancement techniques, advanced image computing methods (including segmentation, registration, motion and shape analysis), machine learning, how medical image computing (MIC) is used in clinical and medical research, and how to identify alternative strategies and employ software tools to solve typical problems in MIC. - An authoritative presentation of key concepts and methods from experts in the field - Sections clearly explaining key methodological principles within relevant medical applications - Self-contained chapters enable the text to be used on courses with differing structures - A representative selection of modern topics and techniques in medical image computing - Focus on medical image computing as an enabling technology to tackle unmet clinical needs - Presentation of traditional and machine learning approaches to medical image computing

The three-volume set LNCS 6891, 6892 and 6893 constitutes the refereed proceedings of the 14th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2011, held in Toronto, Canada, in September 2011. Based on rigorous peer reviews, the program committee carefully selected 251 revised papers from 819 submissions for presentation in three volumes. The third volume includes 82 papers organized in topical sections on computer-aided diagnosis and machine learning, and segmentation.

This book constitutes the refeered proceedings of the 21st International Conference on Information Processing in Medical Imaging, IPMI 2009, held in Williamsburg, VA, USA, in July 2009 The 26 revised full papers and 33 revised poster papers presented were carefully reviewed and selected from 150 submissions. The papers are organized in topical sections on diffusion imaging, PET imaging, image registration, functional networks, space curves, tractography, microscopy, exploratory analyses, features and detection, image guided surgery, shape analysis, motion, and segmentation and validation.

The three-volume set LNCS 6361, 6362 and 6363 constitutes the refereed proceedings of the 13th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2010, held in Beijing, China, in September 2010. Based on rigorous peer reviews, the program committee carefully selected 251 revised papers from 786 submissions for presentation in three volumes. The first volume includes 84 papers organized in topical sections on computer-aided diagnosis, planning and guidance of interventions, image segmentation, image reconstruction and restoration, functional and diffusion-weighted MRI, modeling and simulation, instrument and patient localization and tracking, quantitative image analysis, image registration, computational and interventional cardiology, and diffusion tensor MR imaging and analysis.

The task of object localization in medical images is a corner stone of automatic image processing and a prerequisite for other medical imaging tasks. In this thesis, we present a general framework for the automatic detection and localization of spatially correlated key points in medical images based on a conditional random field (CRF). The problem of selecting suitable potential functions (knowledge sources) and defining a reasonable graph topology w.r.t. the dataset is automated by our proposed data-driven CRF optimization. We show how our fairly simple setup can be applied to different medical datasets involving different image dimensionalities (i.e., 2D and 3D), image modalities (i.e., X-ray, CT, MRI) and target objects ranging from 2 to 102 distinct key points by automatically adapting the CRF to the dataset. While the used general "default" configuration represents an easy to transfer setup, it already outperforms other state-of-the-art methods on three out of four datasets. By slightly gearing the proposed approach to the fourth dataset, we further illustrate that the approach is capable of reaching state-of-the-art performance of highly sophisticated and data-specific deep-learning-based approaches. Additionally, we suggest and evaluate solutions for common problems of graph-based approaches such as the reduced search space and thus the potential exclusion of the correct solution, better handling of spatial outliers using latent variables and the incorporation of invariant higher order potential functions. Each extension is evaluated in detail and the whole method is additionally compared to a rivaling convolutional-neural-network-based approach on a hard problem (i.e., the localization of many locally similar repetitive target key points) in terms of exploiting the spatial correlation. Finally, we illustrate how follow-up tasks, segmentation in this case, may benefit from a correct localization by reaching state-of-the-art performance using off-the-shelve methods in combination with our proposed method.

The three-volume set LNCS 8149, 8150, and 8151 constitutes the refereed proceedings of the 16th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2013, held in Nagoya, Japan, in September 2013. Based on rigorous peer reviews, the program committee carefully selected 262 revised papers from 789 submissions for presentation in three volumes. The 81 papers included in the third volume have been organized in the following topical sections: image reconstruction and motion modeling; machine learning in medical image computing; imaging, reconstruction, and enhancement; segmentation; physiological modeling, simulation, and planning; intraoperative guidance and robotics; microscope, optical imaging, and histology; diffusion MRI; brain segmentation and atlases; and functional MRI and neuroscience applications.

This book constitutes the thoroughly refereed workshop proceedings of the Second International Workshop on Medical Computer Vision, MCV 2012, held in Nice, France, October 2012 in conjunction with the 15th International Conference on Medical Image Computing and Computer Assisted Intervention, MICCAI 2012. The 24 papers have been selected out of 42 submissions. At MCV 2012, 12 papers were presented as a poster and 12 as a poster together with a plenary talk. The book also features four selected papers which were presented at the previous CVPR Medical Computer Vision workshop held in conjunction with the International Conference on Computer Vision and Pattern Recognition on June 21 2012 in Providence, Rhode Island, USA. The papers explore the use of modern computer vision technology in tasks such as automatic segmentation and registration, localization of anatomical features and detection of anomalies, as well as 3D reconstruction and biophysical model personalization.