Management of Periprosthetic Joint Infections (PJIs): Management of PJIs discusses periprosthetic joint infection (PJI), a fairly rare occurrence that is nonetheless one of the most serious complications in joint replacement surgery. Intricate interactions between the pathogen, the host, and the implant can result in PJIs which are not only physically devastating for the patient, but also financially crippling for health authorities and insurance companies. Actions taken to minimize the risk of PJIs can be extremely challenging for the orthopaedic community. Consequently, new research, which is detailed in this comprehensive book, is being undertaken to minimize and manage these challenging infections. - Provides essential background knowledge on the mechanisms and identification of PJIs - Dedicated chapters focus on the complex, but vital eccentricities between PJIs in different areas of the body - Contains contributions from a mixture of clinical and academic experts in the field, thus ensuring balanced coverage

This book outlines the most updated clinical guidelines that are vital for the prevention infections and care of patients with joint infections following a replacement surgery, one of the highest volume medical interventions globally. Sections address the diagnosis, management approaches and prevention of prosthetic joint infections. Written by experts in the field, this text provides a brief overview of the literature and current recommendations in each of the specified areas. Given the rapidly evolving state-of-play in this clinical area, this compendium grows increasingly important to clinicians in their management decisions. Prosthetic Joint Infections is a valuable resource for infectious disease specialists, epidemiologists, surgeons, and orthopedic specialists who may work with patients with prosthetic joint infections.

This book Periprosthetic Joint Infection is a portable guide to the practical management of surgical site infections following orthopedic procedures. It designed to help answer clinician's questions regarding the prevention and treatment of periprosthetic infections. It organized for rapid review, featuring evidence reviews, pitfalls, Rothman Institute Current Practices and Controversies. The guide is being included in the course materials for the 29th Annual Current Concepts in Joint Replacement® (CCJR) meeting thanks to a generous educational grant from 3M Health Care.

Periprosthetic Joint Infection of the Hip and Knee is a practical reference for the diagnosis and treatment of total joint infections following hip and knee arthroplasty. In addition to useful chapters presenting common tests and algorithms used for diagnosis, the book gives background on the epidemiology, risk factors, and prevention strategies of periprosthetic joint infection. Additionally, practical clinical information is given, including antibiotic treatment strategies and delivery methods and medical optimization techniques for physicians to follow for patient care and follow-up. Covering a topic that is currently underrepresented in the medical literature, Periprosthetic Joint Infection of the Hip and Knee will be useful to orthopedic surgeons, rheumatologists, and other physicians involved in the care of patients with hip and knee prosthetic implants.

This book provides an in-depth overview of the aetiology, treatment and prevention of infections following knee arthroplasty. It presents up-to-date information on available techniques and salvage procedures for complex patients with infected, total knee arthroplasty. Divided into 5 sections, this book explores biomaterials, clinical manifestations, diagnosis, treatment and prevention, including preoperative optimisation, in order to reduce knee infections. This book is a valuable reference resource for practicing orthopaedic surgeons, residents, and medical students wishing to understand the fundamental concepts in infectious disease medicine needed in current orthopaedic practice.

The must-have book for candidates preparing for the oral component of the FRCS (Tr and Orth).

This comprehensive, clinically oriented reference details the state-of-the-art approach to infections of bones and joints. Utility for all practitioners is ensured by the wide range of contributors who include infectious disease specialists, rheumatologists, orthopedic surgeons, and radiologists. This is the definitive resource for the clinician who treats orthopedic infections.

Evidence-Based Orthopedics is an up-to-date review of the best evidence for the diagnosis, management, and treatment of orthopedic conditions. Covering orthopedic surgery as well as pre- and post-operative complications, this comprehensive guide provides recommendations for implementing evidence-based practice in the clinical setting. Chapters written by leading clinicians and researchers in the field are supported by tables of evidence that summarize systematic reviews and randomized controlled trials. In areas where evidence is insufficient to recommend a practice, summaries of the available research are provided to assist in decision-making. This fully revised new edition reflects the most recent evidence using the approved evidence-based medicine (EBM) guidelines and methodology. The text now places greater emphasis on GRADE—a transparent framework for developing and presenting summaries of evidence—to allow readers to easily evaluate the quality of evidence and the strength of recommendations. The second edition offers a streamlined presentation and an improved standardized format emphasizing how evidence in each chapter directly affects clinical decisions. Incorporating a vast amount of new evidence, Evidence-Based Orthopedics: Features thoroughly revised and updated content, including a new chapter on pediatric orthopedics and new X-ray images Provides the evidence base for orthopedic surgery as well as pediatric orthopedics and orthopedic conditions requiring medical treatment Covers the different methods for most orthopedic surgical procedures, such as hip replacements, arthroscopy, and knee replacements Helps surgeons and orthopedic specialists achieve a uniform optimum standard through a condition-based approach Aligns with internationally accepted guidelines and best health economic principles Evidence-Based Orthopedics is an invaluable resource for orthopedic specialists, surgeons, trauma surgeons, trainees, and medical students.

During the recent transition between acute diseases caused by swarms of single planktonic bacteria, and chronic infections caused by bacteria growing in slime-enclosed biofilms, a general clinical consensus has emerged that pathologies with bacterial etiologies are frequently culture negative. Because biofilm infections now affect 17 million Americans per year (killing approximately 450,000), the suggestion that these common and lethal infections regularly go unnoticed by the only FDA-approved method for their detection and characterization is a matter of urgent concern. Biologically, we would expect that planktonic bacterial cells would colonize any new surface, including the surface of an agar plate, while the specialized sessile cells of a biofilm community would have no such proclivity. In the study of biofilm diseases ranging from otitis media to prostatitis, it was found that direct microscopy and DNA- and RNA-based molecular methods regularly document the presence of living bacteria in tissues and samples that are culture negative. The editors selected orthopedic biofilm infections as the subject of this book because these infections occur against a background of microbiological sterility in which modern molecular methods would be expected to find bacterial DNA, RNA-based microscopic methods would be expected to locate bacterial cells, and cultures would be negative. Moreover, in Orthopedics we find an already biofilm-adapted surgical group in which current strategies are based on the meticulous removal of compromised tissues, antibiotic options as based on high biofilm-killing local doses, and there are practical bedside strategies for dealing with biofilm infections. So here is where the new paradigm of biofilm infection meets the equally new paradigm of the culture negativity of biofilms, and this volume presents a conceptual synthesis that may soon combine the most effective molecular methods for the detection and identification of bacteria with a surgical discipline that is ready to help patients.

The Editors of “Essentials of Cemented Knee Arthroplasty” have compiled a comprehensive textbook on what many consider the most successful surgical procedure of the century. This book rounds out the compendium previously published by Springer on arthroplasty related topics: “The Well Cemented Total Hip Arthroplasty”, “PMMA Cements”, and “Management of Periprosthetic Joint Infection”. Unique to this text is the high quality contributions from over 160 world wide experts in the field, and provides a unique international perspective on the multifaceted topic of knee replacement surgery. Sections include a focus on Surgical Indications, Implant Design, Novel Technologies, Complications, and Cementing Technique, amongst others. Each Chapter not only draws on the most current literature on the subject, but also crystalizes the most important points into clinically relevant, practically applicable “take home messages”. This singular text is notable for not only its breadth, but also its depth, and will be an invaluable resource for knee arthroplasty surgeons throughout the globe.