Unparalleled in its breadth and depth, this state-of-the-art handbook reviews current scientific advances in understanding trauma and PTSD, discusses the implications for clinical practice, and evaluates the status of evidence-based assessment and treatment. The foremost authorities in the field examine posttraumatic psychological reactions on multiple levels, from genes and neurocircuitry to gender and lifespan development. Established and emerging psychological, medical, and public health interventions are discussed in depth, as are issues in tailoring treatment to the needs of different populations. Special topics include forensic issues, resilience, and prevention. The integrative concluding chapter presents a reasoned agenda for future research.